Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
产品信息
PA5-48004
产品规格
种属反应
Mouse
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Mouse myeloma cell line NS0-derived recombinant mouse IL-27 R alpha/WSX-1/TCCR Gly29-Lys510
偶联物
形式
Lyophilized
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 5% trehalose
内含物
No Preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2610124
产品详细信息
In direct ELISAs, approximately 60% cross-reactivity with recombinant human TCCR is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
靶标信息
In mice, CD4+ helper T-cells differentiate into type 1 (Th1) cells and type 2 (Th2) cells, which are critical for cell-mediated immunity and most antibody responses, respectively. The differentiation of Th1 cells is predominantly under the influence of IL12, while IL4 influences the differentiation of Th2 cells. Mice deficient in these cytokines, their receptors, or associated transcription factors have impaired, but not absent, Th1 or Th2 immune responses. The gene discussed here encodes a protein that is similar to the mouse T-cell cytokine receptor Tccr at the amino acid level and is predicted to be a glycosylated transmembrane protein. Diseases associated with IL27RA include Hyper Ige Recurrent Infection Syndrome 4 and Crisponi/Cold-Induced Sweating Syndrome 2.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: CRL1IL-27R; cytokine receptor family, class 1 (WSXWS), member 1; il-27 receptor; IL-27 receptor subunit alpha; IL-27R subunit alpha; IL-27R-alpha; IL-27RA; Interleukin-27 receptor subunit alpha; T cell cytokine receptor; T cell cytokine receptor; cytokine receptor family, class 1 (WSXWS), member 1; TCCR; Type I T-cell cytokine receptor; WSX-1
基因别名: CRL1; IL-27R; Il27ra; Tccr; WSX-1; Wsx1; zcytor1
UniProt ID: (Mouse) O70394
Entrez Gene ID: (Mouse) 50931
