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A novel gene designated TERE1, has a significant effect on the growth regulation in bladder cancer. The TERE1 gene maps to a chromosome locus that has been identified by loss of heterozygosity studies as a site of a putative tumor suppressor gene or genes for multiple tumor types including prostate carcinoma. Data suggest that TERE1 may be significant in prostate cancer growth regulation and the down regulation or absence of TERE1 may be an important component of the phenotype of advanced disease. Data also suggest a potential role for this gene product in the progression of bladder cancer.
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蛋白别名: RP4-796F18.1; transitional epithelia response protein; Transitional epithelial response protein 1; UbiA prenyltransferase domain-containing protein 1
基因别名: SCCD; TERE1; UBIAD1
UniProt ID: (Human) Q53GX3
Entrez Gene ID: (Human) 29914
分子生物学功能: transferase