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产品信息
14480-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
TFE3 Fusion Protein Ag5863 (1-350 aa encoded by BC026027)
偶联物
Unconjugated
形式
Liquid
浓度
0.25 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MSHAAEPAR DGVEASAEGP RAVFVLLEER RPADSAQLLS LNSLLPESGI VADIELENVL DPDSFYELKS QPLPLRSSLP ISLQATPATP ATLSASSSAG GSRTPAMSSS SSSRVLLRQQ LMRAQAQEQE RRERREQAAA APFPSPAPAS PAISVVGVSA GGHTLSRPPP AQVPREVLKV QTHLENPTRY HLQQARRQQV KQYLSTTLGP KLASQALTPP PGPASAQPLP APEAAHTTGP TGSAPNSPMA LLTIGSSSEK EIDDVIDEII SLESSYNDEM LSYLPGGTTG LQLPSTLPVS GNLLDVYSSQ GVATPAITVS NSCPAELPNI KREISETEAK ALLKERQKKD N (1-350 aa encoded by BC026027)
靶标信息
The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein contains a bipartite nuclear localization signal. This gene is known to escape chromosome X-inactivation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: bHLHe33; Class E basic helix-loop-helix protein 33; mTFE3; transcription factor E family, member A; Transcription factor E3; transcription factor for IgH enhancer; transcription factor for immunoglobulin heavy-chain enhancer 3
基因别名: BHLHE33; F830016E06Rik; RCCP2; RCCX1; RGD1559642; Tcfe3; Tfe-3; TFE3; TFEA
UniProt ID: (Human) P19532, (Mouse) Q64092
Entrez Gene ID: (Human) 7030, (Rat) 317376, (Mouse) 209446
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
transcription regulatory region DNA binding
protein dimerization activity
molecular_function
DNA binding
protein heterodimerization activity
transcription from RNA polymerase II promoter
humoral immune response
biological_process
regulation of osteoclast differentiation
positive regulation of cell adhesion
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
adaptive immune response
immune system process
transcription, DNA-templated
regulation of transcription, DNA-templated
