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TIA-1 isoform p40 Antibody (PA5-80129) in WB
Western blot analysis of TIA-1 in Lane 1: JURKAT cell lysate, Lane 2: RAJI cell lysate, Lane 3: CEM cell lysate, Lane 4: HT1080 cell lysate, Lane 5: K562 cell lysate. Sample was incubated with TIA-1 polyclonal antibody (Product # PA5-80129).
产品信息
PA5-80129
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence at the N-terminus of human TIA1 (98-110aa STQRSQDHFHVFV).
偶联物
Unconjugated
形式
Lyophilized
浓度
500 µg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 5mg BSA
内含物
0.05mg sodium azide, 0.05mg thimerosal
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2747243
产品详细信息
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
靶标信息
Noggin is involved in numerous developmental processes, such as neural tube fusion and joint formation. The morphogenesis of organs is initiated by a downgrowth from a layer of epithelial stem cells. This process is achieved through the receipt of signals from 1) a WNT protein (WNT3A) to stabilize beta-catenin; and 2) Noggin, which is a bone morphogenetic protein inhibitor. Noggin mutations in unrelated families with proximal symphalangism (SYM1) and multiple synostoses syndrome (SYNS1) have been identified, which have multiple joint fusion as their principal defect.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Cytotoxic granule associated RNA binding protein TIA1; cytotoxic granule-associated RNA-binding protein 1; Nucleolysin TIA-1; Nucleolysin TIA-1 isoform p40; p40 TIA 1; p40-TIA-1; p40-TIA-1 (containing p15-TIA-1); RNA-binding protein TIA-1; T-cell-restricted intracellular antigen-1; TIA 1; TIA-1; TIA1 protein; TIAL1; TIAR
基因别名: 2310050N03Rik; AI256674; mTIA-1; Tia; TIA-1; TIA1; WDM
UniProt ID: (Human) P31483, (Mouse) P52912
Entrez Gene ID: (Human) 7072, (Mouse) 21841
apoptotic process
fibroblast growth factor receptor signaling pathway
negative regulation of translation
negative regulation of cytokine biosynthetic process
regulation of mRNA splicing, via spliceosome
protein localization to cytoplasmic stress granule
positive regulation of epithelial cell apoptotic process
