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产品信息
CF809738
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
OTI5C8
抗原
Full length human recombinant protein of human TIMM8A produced in E.coli.
偶联物
形式
Lyophilized
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 8% trehalose
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
靶标信息
Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIMM8-TIMM13 complex mediates the import of proteins such as TIMM23, SLC25A12/ARALAR1 and SLC25A13/ARALAR2, while the predominant TIMM9-TIMM10 70 kDa complex mediates the import of much more proteins. Probably necessary for normal neurologic development.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Deafness dystonia protein 1; Deafness dystonia protein 1 homolog; deafness/dystonia peptide; Mitochondrial import inner membrane translocase subunit Tim8 A; translocase of inner mitochondrial membrane 8 homolog a; translocase of inner mitochondrial membrane 8 homolog a1; X-linked deafness dystonia protein
基因别名: DDP; DDP1; DFN1; DXHXS1274E; Fci-12; MTS; TIM8; TIM8A; TIMM8A; Timm8a1
UniProt ID: (Human) O60220, (Mouse) Q9WVA2, (Rat) Q9WVA1
Entrez Gene ID: (Human) 1678, (Mouse) 30058, (Rat) 84383
