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Proteintech

TIP47 Polyclonal Antibody

35 篇参考文献

查看其他17个TIP47抗体

说明书

实验方案

技术支持

货号 10694-1-AP

此产品在中国无法购买

150 µL

说明书

实验方案

技术支持

抗体检测数据 (13)

Application

TIP47 Antibody in Immunocytochemistry (ICC/IF)

图: 1 / 13

TIP47 Antibody (10694-1-AP) in ICC/IF

Immunofluorescent analysis of (-20°C Ethanol) fixed oleic acid treated HeLa cells using TIP47 antibody (Product # 10694-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). F-actin was stained with CL594-phalloidin.

TIP47 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

TIP47 Antibody in Immunoprecipitation (IP)

Product Image Gallery

产品信息

10694-1-AP

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:2500

查看25篇已发表文章 25篇已发表文章

免疫组化 (IHC)

查看3篇已发表文章 3篇已发表文章

免疫组化（石蜡） (IHC (P))

1:50-1:500

免疫细胞化学 (ICC/IF)

1:20-1:200

查看6篇已发表文章 6篇已发表文章

流式细胞分析 (Flow)

0.2 µg/1x10^6 cells

免疫沉淀 (IP)

0.5-4.0 µg

不适用 (N/A)

查看1篇已发表文章 1篇已发表文章

产品规格

种属反应

Human, Mouse

已发表种属

Human, Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

TIP47 Fusion Protein Ag1028 (134-434 aa encoded by BC007566)

查看免疫原

偶联物

Unconjugated

形式

Liquid

浓度

0.2 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice (domestic); Dry ice (international)

产品详细信息

Immunogen sequence: EMVSSAKDT VATQLSEAVD ATRGAVQSGV DKTKSVVTGG VQSVMGSRLG QMVLSGVDTV LGKSEEWADN HLPLTDAELA RIATSLDGFD VASVQQQRQE QSYFVRLGSL SERLRQHAYE HSLGKLRATK QRAQEALLQL SQALSLMETV KQGVDQKLVE GQEKLHQMWL SWNQKQLQGP EKEPPKPEQV ESRALTMFRD IAQQLQATCT SLGSSIQGLP TNVKDQVQQA RRQVEDLQAT FSSIHSFQDL SSSILAQSRE RVASAREALD HMVEYVAQNT PVTWLVGPFA PGITEKAPEE KK (134-434 aa encoded by BC007566)

靶标信息

TIP47 has been described as cargo protein involved in the trafficking of the mannose-6-phosphate receptor between endosomes and the Golgi complex. Mannose 6-phophate receptors (MPRs) deliver lysosomal hydrolase from the Golgi to endosomes and then return to the Golgi complex. The protein encoded by this gene interacts with the cytoplasmic domains of both cation-independent and cation-dependent MPRs and is required for endosome to Golgi transport. This protein also binds directly to the GTPase RAB9, a member of the RAS oncogene family. The interaction with RAB9 has been shown to increase the affinity of this protein for its cargo. TIP47 has been localized in milk fat globule membranes of human and bovine origin. It has been described as a placental protein, as well. Increased amounts of TIP47 are secreted into circulation of cervix carcinoma patients. Therefore, this protein is probably significant as an oncodevelopmental marker.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

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生物信息学

蛋白别名: 47 kDa mannose 6-phosphate receptor-binding protein; 47 kDa MPR-binding protein; Cargo selection protein TIP47; mannose-6-phosphate receptor binding protein 1; Mannose-6-phosphate receptor-binding protein 1; MGC11117; MGC2012; Perilipin-3; Placental protein 17; PP17; tail-interacting protein, 47 kD; testicular tissue protein Li 114

基因别名: 1300012C15Rik; M6PRBP1; PLIN3; PP17; TIP47

UniProt ID: (Human) O60664, (Mouse) Q9DBG5

Entrez Gene ID: (Human) 10226, (Mouse) 66905

功能

protein binding cadherin binding involved in cell-cell adhesion scaffold/adaptor protein

参与通路

vesicle-mediated transport cell-cell adhesion transport

TIP47 Polyclonal Antibody

TIP47 Antibody (10694-1-AP) in ICC/IF

产品信息

10694-1-AP

免疫印迹 (WB)

免疫组化 (IHC)

免疫组化（石蜡） (IHC (P))

免疫细胞化学 (ICC/IF)

流式细胞分析 (Flow)

免疫沉淀 (IP)

不适用 (N/A)

种属反应

已发表种属

宿主/亚型

分类

类型

抗原

偶联物

形式

浓度

纯化类型

保存液

内含物

保存条件

运输条件

产品详细信息

靶标信息

生物信息学

性能保障

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