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产品信息
PA5-66477
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
偶联物
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2662137
产品详细信息
Immunogen sequence: MEPGMLGPHNL PHHEPISFG
Highest antigen sequence identity to the following orthologs - mouse 75%, rat 80%.
靶标信息
The Hox proteins play a role in patterns of embryonic development and cellular differentiation by regulating downstream target genes. TLX2, also known as homeobox11-like 1 (HOX11L1), is a DNA-binding nuclear transcription factor that appears to be crucial for the development of the peripheral nervous system. TLX2 is a downstream target of regulation by both PHOX2A and PHOX2B proteins during intestinal neuronal differentiation. In humans, loss-of-function of TLX2 may play a role in tumorigenesis of gastrointestinal stromal tumors.
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生物信息学
蛋白别名: homeo box 11-like 1; homeobox 11-like1; Homeobox protein Hox-11L1; Neural crest homeobox protein; T-cell leukemia homeobox protein 2
基因别名: HOX11L1; NCX; TLX2
UniProt ID: (Human) O43763
Entrez Gene ID: (Human) 3196
