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TMPRSS11D Antibody (PA5-87660) in WB
Western blot analysis of TMPRSS11D in extracts of various cell lines. Samples were incubated with TMPRSS11D Polyclonal antibody (Product # PA5-87660) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
产品信息
PA5-87660
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 42-292 of human TMPRSS11D (NP_0042531)
偶联物
形式
Liquid
浓度
1.24 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2804329
产品详细信息
Immunogen sequence: AFDQKSYFYR SSFQLLNVEY NSQLNSPATQ EYRTLSGRIE SLITKTFKES NLRNQFIRAH VAKLRQDGSG VRADVVMKFQ FTRNNNGASM KSRIESVLRQ MLNNSGNLEI NPSTEITSLT DQAAANWLIN ECGAGPDLIT LSEQRILGGT EAEEGSWPWQ VSLRLNNAHH CGGSLINNMW ILTAAHCFRS NSNPRDWIAT SGISTTFPKL RMRVRNILIH NNYKSATHEN DIALVRLENS VTFTKDIHSV C; Positive Samples: HepG2, Mouse liver, Mouse kidney, Mouse skeletal muscle, Rat liver, Rat kidney; Cellular Location: Cell membrane, Single-pass type II membrane protein
靶标信息
The interleukin 17 receptor E (IL-17RE) shares limited similarity to the receptor of IL-17A, a ubiquitous type I membrane glycoprotein that with IL-17A plays a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. IL-17RE is the functional receptor of IL-17C and has been suggested to mediate mucosal immunity to infection with intestinal pathogens. IL-17C is produced by epithelia in response to bacterial challenge and binds to a receptor complex formed by IL-17RE and IL-17RA on the epithelial cell surface, thereby regulating the immune function of epithelial cells in an autocrine manner.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Adrenal secretory serine protease; airway spesific trypsin-like protease; airway trypsin like protease; Airway trypsin-like protease; AsP; AT; MGC150587; MGC150588; Transmembrane protease serine 11D; transmembrane serine protease 11D
基因别名: AsP; AST; BC020151; HAT; Mat; Rat; TMPRSS11D
UniProt ID: (Human) O60235, (Rat) Q8VHJ4, (Mouse) Q8VHK8
Entrez Gene ID: (Human) 9407, (Rat) 64565, (Mouse) 231382
