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This gene encodes a leucine-rich transmembrane glycoprotein that may be involved in cell adhesion. The encoded protein is an oncofetal antigen that is specific to trophoblast cells. In adults this protein is highly expressed in many tumor cells and is associated with poor clinical outcome in numerous cancers. Alternate splicing in the 5' UTR results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2009].
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 5T4 oncofetal antigen; 5T4 oncofetal trophoblast glycoprotein; 5T4 oncotrophoblast glycoprotein; 5T4-AG; M6P1; Trophoblast glycoprotein; WAIF1; Wnt-activated inhibitory factor 1
基因别名: 5T4; 5T4AG; AW495680; M6P1; TPBG; WAIF1
UniProt ID: (Human) Q13641, (Mouse) Q3UPI2, (Rat) Q5PQV5
Entrez Gene ID: (Human) 7162, (Mouse) 21983, (Rat) 83684