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产品信息
PA5-62007
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2648863
产品详细信息
Immunogen sequence: KDLAALRVQL REQHLYYQDQ LLPVSRIIV
Highest antigen sequence identity to the following orthologs: Mouse - 59%, Rat - 59%.
靶标信息
Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. Although this gene may be an exception, most of the tryptase genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders. TPSD1 was once considered to be a pseudogene, although it is now believed to be a functional gene that encodes a protein.
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生物信息学
蛋白别名: Delta-tryptase; HmMCP-3-like tryptase III; Mast cell mMCP-7-like; mast cell tryptase; mMCP-7-like delta II tryptase; mMCP-7-like-1; mMCP-7-like-2; Tryptase delta; Tryptase-3
基因别名: MCP7-LIKE; MCP7L1; MMCP-7L; TPSD1
UniProt ID: (Human) Q9BZJ3
Entrez Gene ID: (Human) 23430
