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NeoBiotechnologies
TREM2 (Triggering Receptor Expressed On Myeloid Cells 2) Monoclonal Antibody (TREM2/7210)
产品信息
54209-MSM1-P1ABX
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Monoclonal
类型
Antibody
克隆号
TREM2/7210
抗原
Recombinant fragment (around aa1-200) of human TREM2 protein.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A/G
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
靶标信息
TREM2 is a membrane protein that forms a receptor signaling complex with TYROBP. The encoded protein may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: OTTHUMP00000039771; soluble TREM 2; soluble TREM2; sTREM 2; sTREM2; TREM; TREM-2; Triggering receptor expressed on monocytes 2; Triggering receptor expressed on myeloid cells; Triggering receptor expressed on myeloid cells 2; triggering receptor expressed on myeloid cells 2a
基因别名: TREM-2; TREM2; Trem2a; Trem2b; Trem2c
UniProt ID: (Human) Q9NZC2
Entrez Gene ID: (Human) 54209
positive regulation of antigen processing and presentation of peptide antigen via MHC class II
phagocytosis, engulfment
humoral immune response
detection of lipopolysaccharide
detection of peptidoglycan
innate immune response
positive regulation of peptidyl-tyrosine phosphorylation
regulation of immune response
positive regulation of calcium-mediated signaling
positive regulation of ERK1 and ERK2 cascade
detection of lipoteichoic acid
cellular response to lipoteichoic acid
cellular response to peptidoglycan
dendritic cell differentiation
positive regulation of protein localization to plasma membrane
positive regulation of C-C chemokine receptor CCR7 signaling pathway
positive regulation of CD40 signaling pathway
