Invitrogen

TRH Polyclonal Antibody

高级验证

This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.

3个已发表图片

3 篇参考文献

查看其他5个TRH抗体

说明书

实验方案

技术支持

说明书

实验方案

技术支持

TRH Antibody in Immunohistochemistry (IHC)

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TRH Antibody (PA5-57331) in IHC

Immunohistochemical staining of TRH in human hypothalamus using a TRH Polyclonal Antibody (Product # PA5-57331) shows strong positivity neuronal processes and subsets of neuronal cells and .

Product Image Gallery

TRH Antibody — Relative expression in different tissues in IHC: Detection of differential expression levels of TRH demonstrates antibody specificity. Immunohistochemical analysis of TRH using anti-TRH Polyclonal Antibody (Product # PA5-57331), shows significant staining of TRH in human cervix, uterine and shows minimal or weak staining in human skeletal muscle tissues. The relative expression levels of TRH within each tissue is shown using RNA-Seq. {RE}

产品信息

PA5-57331

应用

建议稀释比

已发表文章

免疫组化 (IHC)

1:1,000-1:2,500

查看2篇已发表文章 2篇已发表文章

其他PubMed (Misc)

查看1篇已发表文章 1篇已发表文章

产品规格

种属反应

Human

已发表种属

Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein corresponding to Human TRH. Recombinant protein control fragment (Product #RP-96454).

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.50 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 40% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

RRID

AB_2648903

产品详细信息

Immunogen sequence: HKRQHPGRRE DEASWSVDVT QHKRQHPGRR SPWLAYAVPK RQHPGRRLAD PKAQRSWEE

Highest antigen sequence identity to the following orthologs: Mouse - 51%, Rat - 50%.

靶标信息

This gene encodes a member of the thyrotropin-releasing hormone family. Cleavage of the encoded proprotein releases mature thyrotropin-releasing hormone, which is a tripeptide hypothalamic regulatory hormone. The human proprotein contains six thyrotropin-releasing hormone tripeptides. Thyrotropin-releasing hormone is involved in the regulation and release of thyroid-stimulating hormone, as well as prolactin. Deficiency of this hormone has been associated with hypothalamic hypothyroidism.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Neurochemical phenotype of growth hormone-responsive cells in the mouse paraventricular nucleus of the hypothalamus.

The Journal of comparative neurology

Quaresma PGF,Dos Santos WO,Wasinski F,Metzger M,Donato J

PA5-57331 was used in Immunohistochemistry-immunofluorescence to show that growth hormone action on neurons of the paraventricular nucleus of the hypothalamus, is involved in the regulation of the thyroid, somatotropic and adrenal endocrine axes.

Thu Apr 15 00:00:00 EDT 2021

Differences between rats and mice in the leptin action on the paraventricular nucleus of the hypothalamus: Implications for the regulation of the hypothalamic-pituitary-thyroid axis.

Journal of neuroendocrinology