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产品信息
PA5-111698
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2857108
产品详细信息
Immunogen sequence: QIAETLSNIE RLKLEVQKYE AWLAEAESRV LSNRGDSLSR HARPPDPPAS APPDSSSNSA SQDTKESSEE
靶标信息
Required for translocation of GLUT4 to the plasma membrane in response to insulin signaling. Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by recruiting WASL/N-WASP which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells. May be required for the lysosomal retention of FASLG/FASL.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Cdc42-interacting protein 4; hSTP; Protein Felic; Salt tolerant protein; salt tolerator; Thyroid receptor-interacting protein 10; TR-interacting protein 10
基因别名: CIP4; HSTP; STOT; STP; TRIP-10; TRIP10
UniProt ID: (Human) Q15642
Entrez Gene ID: (Human) 9322
