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For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of mitochondrial tRNA(Lys), tRNA(Glu) and tRNA(Gln). Required for the formation of 5-taurinomethyl-2- thiouridine (tm5s2U) of mitochondrial tRNA(Lys), tRNA(Glu), and tRNA(Gln) at the wobble position. ATP is required to activate the C2 atom of the wobble base.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: lung cancer associated lncRNA 3; mitochondrial 5-methylaminomethyl-2-thiouridylate-methyltransferase; Mitochondrial tRNA-specific 2-thiouridylase 1; MTO2 homolog; tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 1; tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
基因别名: 1110005N20Rik; 1600025P05Rik; AI314320; LCAL3; MTO2; MTU1; TRMT; TRMT1; TRMU; TRNT1
UniProt ID: (Human) O75648, (Mouse) Q9DAT5
Entrez Gene ID: (Human) 55687, (Dog) 481204, (Mouse) 72026
分子生物学功能:
RNA metabolism protein
RNA methyltransferase
nucleic acid metabolism protein