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产品信息
20320-1-AP
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
TSPAN32 Fusion Protein Ag14174 (100-202 aa encoded by BC016693)
偶联物
形式
Liquid
浓度
0.19 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: LAFCAQVQV VFWRLHSPTQ VEDAMLDTYD LVYEQAMKGT SHVRRQELAA IQDVFLCCGK KSPFSRLGST EADLCQGEEA AREDCLQGIR SFLRTHQQVA SSLT (100-202 aa encoded by B C016693)
靶标信息
This gene, which is a member of the tetraspanin superfamily, is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of chromosome 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian and breast cancers. This gene is located among several imprinted genes; however, this gene, as well as the tumor-suppressing subchromosomal transferable fragment 4, escapes imprinting. This gene may play a role in malignancies and diseases that involve this region, and it is also involved in hematopoietic cell function. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: AML1-regulated transmembrane protein 1; FLJ17158; FLJ97586; MGC22455; pan hematopoietic expression; pan-hematopoietic expression protein; Protein Phemx; tetraspanin; Tetraspanin-32; Tspan-32; tumor-suppressing STF cDNA 6; tumor-suppressing subchromosomal transferable fragment 6; tumor-suppressing subchromosomal transferable fragment cDNA 6; tumor-suppressing subtransferable candidate 6
基因别名: Art-1; ART1; AW208513; BB235973; D7Wsu37e; PHEMX; PHMX; TSPAN32; TSSC6
UniProt ID: (Human) Q96QS1, (Mouse) Q9JHH2
Entrez Gene ID: (Human) 10077, (Mouse) 27027
cytoskeleton organization
integrin-mediated signaling pathway
blood coagulation
hemostasis
negative regulation of cell proliferation
negative regulation of myeloid dendritic cell activation
defense response to protozoan
regulation of defense response to virus
platelet aggregation
cell surface receptor signaling pathway
cell-cell signaling
