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This Antibody was verified by Knockout to ensure that the antibody binds to the antigen stated.
For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
TTLL12 (tubulin tyrosine ligase-like family, member 12) is a 644 amino acid protein that contains one TTL domain. Of the fourteen members of the TTLL family that modify tubulin, TTLL12 is the least characterized member. TTLL12 is highly expressed in a multitude of metastatic prostate cancer cell lines, therefore, it is considered a target for tumor therapy. Overexpression of TTLL12 is suggested to alter chromosome ploidy, whereas downregulation of TTLL12 influence several post-translational modifications of tubulin.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Inactive tubulin--tyrosine ligase-like protein 12; tubulin tyrosine ligase-like family member 12; tubulin tyrosine ligase-like family, member 12; Tubulin--tyrosine ligase-like protein 12
基因别名: dJ526I14.2; KIAA0153; RGD1305319; TTLL12
UniProt ID: (Human) Q14166
Entrez Gene ID: (Human) 23170, (Rat) 300105