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Invitrogen
TTR Monoclonal Antibody (2E10C5)
高级验证
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
图: 1 / 4
TTR Antibody (MA1-221) in WB
Western blot analysis of TTR antibody was performed by loading 1000 ng, 500 ng, 250 ng, 125 ng, 62.5 ng and 31.25 ng of a Human Transthyretin Recombinant protein, 1000 ng and 500 ng of BSA and 5 µl PageRuler Plus Prestained Protein Ladder (Product # 26619) onto a 4-20% Tris-Glycine polyacrylamide gel. Proteins were transferred to a nitrocellulose membrane using the G2 Fast Blotter (Product # 62288) and blocked with 5% milk in TBST for at least 1 hour at room temperature. Transthyretin was detected at ~46 kD using a TTR mouse monoclonal ant... View More
产品信息
MA1-221
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
2E10C5
抗原
Purified recombinant fragment of human TTR (AA: 1-147) expressed in E. Coli
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2725592
产品详细信息
MA1-221 detects Transthyretin protein in ELISA and Western Blot applications.
The MA1-221 immunogen is the purified recombinant fragment of human TTR (AA: 1-147) expressed in E. Coli.
靶标信息
Transthyretin (TTR), generally called prealbumin, is a plasma protein that plays an important role in physiology such as a transporter of hormone thyroxine and retinal-binding protein. After produced primarily in the liver, TTR is excreted into the plasma. TTR represents a disproportionate fraction (25%) of CSF protein, prompting the suggestion that it is either selectively transported across the blood-CSF barrier or synthesized de novo within the central nervous system. Transthyretin is a constituent found to the neuritic plaques, neurofibrillary tangles, and microangiopathic lesions of senile cerebral amyloid. It has been reported that more than 40 different mutations in the TTR gene associated with amyloid deposition.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Amyloidosis I; ATTR; carpal tunnel syndrome 1; epididymis luminal protein 111; pre-albumin; Prealbumin; prealbumin, amyloidosis type I; TBPA; thyroxine-binding prealbumin; Transthyretin
基因别名: CTS; CTS1; HEL111; HsT2651; PALB; TBPA; TTR
UniProt ID: (Human) P02766
Entrez Gene ID: (Human) 7276
