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Immunogen sequence: EVQLQTVIN NQSLWDEMLQ NKGLTVIDVY QAWCGPCRAM QPLFRKLKNE LNEDEILHFA VAEADNIVTL QPFRDKCEPV FLFSVNGKII EKIQGANAPL VNKKVINLID EERKIAAGEM ARPQYPEIPL VDSDSEVSEE SPCESVQELY SIAIIKPDAV ISKKVLEIKR KITKAGFIIE AEHKTVLTEE QVVNFYSRIA DQRDFEEFVS FMTSGLSYIL VVSQGSKHNP PSEETEPQTD TEPNERSEDQ PEVEAQVTPG MMKNKQDSLQ EYLERQHLAQ LCDIEEDAAN VAKFMDAFFP DFKKMKSMKL EKTLALLRPN LFHERKDDVL RIIKDEDFKI LEQRQVVLSE KEAQALCKEY ENEDY (7-370 aa encoded by BC036816)
This gene encodes a protein with an N-terminal thioredoxin domain and three C-terminal nucleoside diphosphate kinase (NDK) domains, but the NDK domains are thought to be catalytically inactive. The sea urchin ortholog of this gene encodes a component of sperm outer dynein arms, and the protein is implicated in ciliary function. Mutations in this gene are implicated in primary ciliary dyskinesia type 6.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 3'-5' exonuclease NME8; epididymis secretory protein Li 99; NM23-H8; NME/NM23 family member 8; sperm-specific thioredoxin 2; Spermatid-specific thioredoxin-2; spermatid-specific thioredoxin-2 protein; Sptrx-2; thioredoxin domain containing 3 (spermatozoa); Thioredoxin domain-containing protein 3
基因别名: 1700056P15Rik; CILD6; HEL-S-99; NM23-H8; NME8; Sptrx-2; SPTRX2; TXNDC3
UniProt ID: (Human) Q8N427, (Mouse) Q715T0
Entrez Gene ID: (Human) 51314, (Rat) 364729, (Mouse) 73412