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Positive Control: H1299
Predicted Reactivity: Mouse (99%), Rat (99%), Zebrafish (92%), Chicken (93%), Bovine (100%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Talin, a multifunctional constituent of cell-substratum attachment sites, is a high molecular weight protein (225-235 kDa) found in variety of tissues and cell types. It is localized at a subset of adherens junctions, specialized cell-cell and cell-matrix associations that are characterized by the presence of filamentous actin at the cytoplasmic face of the junctional complex. In cultured cells, talin is absent from cell-cell junctions and found predominantly at adhesion plaques and in fibrillar streaks underlying cell surface fibronectin. Talin interacts with at least two other proteins that are localized at adhesion plaques, vinculin and integrin.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Talin-1
基因别名: ILWEQ; KIAA1027; TLN; TLN1
UniProt ID: (Human) Q9NZQ2
Entrez Gene ID: (Human) 7094, (Rat) 313494