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NeoBiotechnologies
Tenascin C Recombinant Rabbit Monoclonal Antibody (TNC, 2981R)
产品信息
3371-RBM2-P1
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
TNC, 2981R
抗原
Recombinant human full-length TNC protein
偶联物
形式
Liquid
浓度
200 µg/mL
纯化类型
Protein A/G
保存液
PBS, pH 7.4, with 0.05% BSA
内含物
0.05% sodium azide
保存条件
4° C
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
This antibody does not react with Rat.
Immunohistochemistry (PFA fixed): incubate antibody for 30 min at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris Buffer with 1mM EDTA, pH 9.0, for 45 min at 95 degrees C followed by cooling at RT for 20 minutes.
靶标信息
Tenascin is a high molecular weight, multifunctional, extracellular matrix glycoprotein expressed in association with mesenchymal-epithelial interactions during development and in the neovasculature and stroma of undifferentiated tumors (Erickson and Bourdon 1989). It has been described under a variety of names: cytotactin, hexabrachion protein, J1, myotendinous antigen (MI) and glioma mesenchymal extracellular matrix (GMEM). The tenascin molecule is a disulfide-linked hexamer. The expression of tenascin is associated with development and growth, both normal and pathological, whereas the distribution in normal adult tissue is restricted.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Cytotactin; deafness, autosomal dominant 56; Glioma-associated-extracellular matrix antigen; GMEM; GP 150-225; Hexabrachion; hexabrachion (tenascin); JI; MGC144208; MGC144209; MGC167029; Myotendinous antigen; Neuronectin; Tenascin; Tenascin-C; tenascin-C additional domain 1; tenascin-C isoform 14/AD1/16; TN; TN-C
基因别名: 150-225; DFNA56; GMEM; GP; HXB; JI; TN; TN-C; TNC
UniProt ID: (Human) P24821
Entrez Gene ID: (Human) 3371
osteoblast differentiation
cell adhesion
negative regulation of cell adhesion
neuromuscular junction development
positive regulation of cell proliferation
response to wounding
response to mechanical stimulus
positive regulation of gene expression
peripheral nervous system axon regeneration
extracellular matrix organization
wound healing
odontogenesis of dentin-containing tooth
response to ethanol
bud outgrowth involved in lung branching
mesenchymal-epithelial cell signaling involved in prostate gland development
prostate gland epithelium morphogenesis
cellular response to retinoic acid
cellular response to vitamin D
response to fibroblast growth factor
cellular response to prostaglandin D stimulus
