Search Thermo Fisher Scientific
Invitrogen
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
Immunogen sequence: LSPLTNGLDK SYPMEPMVNG GGYPYESASR AGPAHAGHTA PMRPSYSAQE GLAGYQREGP HPAWPQPVTT SHYAHDPSGM FRSQS
Highest antigen sequence identity to the following orthologs: Mouse - 74%, Rat - 74%.
Tensin is involved in the maintenance of cellular structure by anchoring Actin filaments at the focal adhesion via F-Actin binding and capping activities. However, tensin also contains a Src homology 2 (SH2) domain and has the ability to be phosphorylated. Tensin is phosphorylated on tyrosine, serine, and threonine residues, suggesting that it might participate in signal transduction cascades. These diverse characteristics in a single molecule indicate that tensin may be an important link between the cytoskeleton and signal transduction pathways.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: DKFZp586K0617; matrix-remodelling associated 6; Matrix-remodelling-associated protein 6; MGC88584; protein phosphatase 1, regulatory subunit 155; Tensin-1
基因别名: MST091; MST122; MST127; MSTP091; MSTP122; MSTP127; MXRA6; PPP1R155; TNS; TNS1
UniProt ID: (Human) Q9HBL0
Entrez Gene ID: (Human) 7145
分子生物学功能:
non-motor actin binding protein