Invitrogen

Thrombomodulin Monoclonal Antibody (461714)

Thrombomodulin Antibody in Immunocytochemistry (ICC/IF)

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Thrombomodulin Antibody (MA5-24181) in ICC/IF

Immunocytochemistry analysis of Thrombomodulin in immersion fixed bEnd.3 mouse endothelioma cell line. Samples were incubated in Thrombomodulin monoclonal antibody (Product # MA5-24181) using a dilution of 10 µg/mL for 3 hours at room temperature followed by NorthernLights™ 557-conjugated Anti-Rat IgG Secondary Antibody (red) and counterstained with DAPI (blue).

Thrombomodulin Antibody in Immunohistochemistry (Frozen) (IHC (F))

Thrombomodulin Antibody in Flow Cytometry (Flow)

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产品信息

MA5-24181

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1 µg/mL

免疫组化（冰冻） (IHC (F))

8-25 µg/mL

免疫细胞化学 (ICC/IF)

8-25 µg/mL

流式细胞分析 (Flow)

2.5 µg per million cells

产品规格

种属反应

Mouse

宿主/亚型

Rat / IgG2B

分类

Monoclonal

类型

Antibody

克隆号

461714

抗原

Mouse myeloma cell line NS0-derived recombinant mouse Thrombomodulin/BDCA-3 Leu17-Ser517

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Lyophilized

浓度

0.5 mg/mL

纯化类型

Protein A/G

保存液

PBS with 5% trehalose

内含物

No Preservative

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_2609392

产品详细信息

In direct ELISAs and Western blots, no cross-reactivity with recombinant human (rh) Thrombomodulin is observed.

Reconstitute at 0.5 mg/mL in sterile PBS.

靶标信息

Thrombomodulin (TM) is also known as Fetomodulin (FM), endothelial anticoagulant protein, or glycoprotein P112. Thrombomodulin contains six repeated domains homologous with epidermal growth factor (EGF) and an amino terminal domain homologous to lectin-like protein. Through its accelerated activation of protein C, synthesis of TM is one of several mechanisms important in maintaining thrombo-resistance and thus reducing clot formation on the surface of the endothelial cells. Immunohistochemical staining of formalin-fixed tissue for TM has been used for the study of a variety of vascular tumors, meningiomas and choriocarcinomas.

仅用于科研。不用于诊断过程。未经明确授权不得转售。