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Torsin 1A Antibody (MA5-42926) in WB
Western blot analysis of Torsin 1A in extracts of various cell lines. Samples were incubated with Torsin 1A Monoclonal antibody (Product # MA5-42926) using a dilution of 1:500, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s.
产品信息
MA5-42926
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
4Q2I9
抗原
A synthetic peptide corresponding to a sequence within amino acids 233-332 of human TorsinA/TOR1A (O14656).
偶联物
形式
Liquid
浓度
0.9 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 0.05% BSA, 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2912067
产品详细信息
Positive test controls include: 293T, HepG2, U-87MG, Mouse liver, Mouse brain, Mouse spleen, Rat lung.
Immunogen sequence: LKDIEHALSV SVFNNKNSGF WHSSLIDRNL IDYFVPFLPL EYKHLKMCIR VEMQSRGYEI DEDIVSRVAE EMTFFPKEER VFSDKGCKTV FTKLDYYYDD
靶标信息
The protein encoded by this gene is a member of the AAA family of adenosine triphosphatases (ATPases), is related to the Clp protease/heat shock family and is expressed prominently in the substantia nigra pars compacta. Mutations in this gene result in the autosomal dominant disorder, torsion dystonia 1.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: dystonia 1; Dystonia 1 protein; Dystonia 1 torsion; dystonia 1, torsion (autosomal dominant; dystonia 1, torsion (autosomal dominant; torsin A); Torsin 1A; torsin A; Torsin ATPase 1; Torsin ATPase-1A; Torsin family 1 member A; torsin family 1, member A (torsin A); Torsin-1A
基因别名: DQ2; DYT1; TA; TOR1A; TORA; torsinA
UniProt ID: (Human) O14656, (Rat) Q68G38, (Mouse) Q9ER39
Entrez Gene ID: (Human) 1861, (Rat) 266606, (Mouse) 30931
protein deneddylation
response to oxidative stress
organelle organization
nuclear envelope organization
cell adhesion
neuron projection development
protein localization to nucleus
wound healing, spreading of cells
intermediate filament cytoskeleton organization
synaptic vesicle transport
chaperone mediated protein folding requiring cofactor
protein homooligomerization
regulation of dopamine uptake involved in synaptic transmission
chaperone-mediated protein folding
ER-associated misfolded protein catabolic process
nuclear membrane organization
chaperone-mediated protein transport
positive regulation of synaptic vesicle endocytosis
regulation of protein localization to cell surface
