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Invitrogen
Transferrin Polyclonal Antibody
高级验证
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
产品信息
PA5-29568
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein fragment corresponding to a region within amino acids 261 and 525 of Human Transferrin
偶联物
形式
Liquid
浓度
0.51 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 20% glycerol
内含物
0.025% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2547044
产品详细信息
Recommended positive controls: HepG2, rat plasma.
Predicted reactivity: Chimpanzee (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
Transferrins (Tf) are an approximately 80kDa blood plasma glycoprotein synthesized by the liver. They are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Transferrin is the primary blood iron transport protein and under normal conditions; approximately one-third of total blood transferrin contains bound iron. Measurement of blood transferrin levels can be used as an indicator for blood iron-carrying capacity and abnormalities of iron metabolism such as anaemia, iron overload and haemochromatosis.Serum transferrin may also have a further role in stimulating cell proliferation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Beta-1 metal-binding globulin; DKFZp781D0156; epididymis secretory sperm binding protein Li 71p; Liver regeneration-related protein LRRG03; Serotransferrin; Siderophilin; transferin; Transferrin
基因别名: HEL-S-71p; PRO1400; PRO1557; PRO2086; TF; Tfn; TFQTL1; Trf
UniProt ID: (Human) P02787, (Rat) P12346
Entrez Gene ID: (Human) 7018, (Rat) 24825
retina homeostasis
platelet degranulation
cellular iron ion homeostasis
regulation of protein stability
transferrin transport
positive regulation of receptor-mediated endocytosis
iron ion homeostasis
cellular response to iron ion
ferrous iron import into cell
response to hypoxia
iron ion transport
apoptotic process
acute-phase response
actin filament organization
activation of JUN kinase activity
small GTPase mediated signal transduction
response to lead ion
response to organic cyclic compound
ferric iron transport
osteoclast differentiation
positive regulation of myelination
positive regulation of phosphorylation
positive regulation of bone resorption
positive regulation of transcription, DNA-templated
SMAD protein signal transduction
ERK1 and ERK2 cascade
positive regulation of oligodendrocyte progenitor proliferation
cellular response to cAMP
cellular response to follicle-stimulating hormone stimulus
positive regulation of cell motility
