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Transferrin Receptor Antibody (MA1-80015) in WB
Western blot was performed using Anti-Transferrin Receptor Monoclonal Antibody (YTA74.4) (Product # MA1-80015) and a 84kDa band corresponding to Transferrin Receptor was observed along with uncharacterized band (*) across tissues tested. Tissue extracts (50 µg lysate) of Mouse Spleen (Lane 1), Mouse Thymus (Lane 2), Mouse Skeletal Muscle (Lane 3), Mouse Kidney (Lane 4), Mouse Liver (Lane 5), Mouse Heart (La... View More
产品信息
MA1-80015
应用
建议稀释比
已发表文章
产品规格
种属反应
Mouse
宿主/亚型
Rat
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
YTA74.4
抗原
Murine Concanavilin A activated spleen cells.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_929355
产品详细信息
For FACS analysis, use 10 µL of the suggested working dilution to label 1x10^6 cells in 100 µL.
Rat anti Mouse CD71 antibody, clone YTA74.4 recognizes the mouse Transferrin receptor protein 1 also known as CD71 or TfR1.
靶标信息
Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Serum transferrin receptor (sTfR) is used as a means of detecting erythropoietin (EPO) misuse by athletes and as a diagnostic test for anemias resulting from a number of conditions including rheumatoid arthritis, pregnancy, irritable bowel syndrome and in HIV patients.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CD antigen CD71; CD71; mammary tumor virus receptor 1; TR; Transferrin receptor protein 1
基因别名: 2610028K12Rik; AI195355; AI426448; AU015758; CD71; E430033M20Rik; Mtvr-1; Mtvr1; p90; TFR; TFR1; Tfrc; TR; Trfr
UniProt ID: (Mouse) Q62351
Entrez Gene ID: (Mouse) 22042
