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产品信息
MA5-44637
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2b
分类
Monoclonal
类型
Antibody
克隆号
3-E11
抗原
Synthetic peptide within human Prealbumin PA aa 100-147.
偶联物
形式
Liquid
浓度
2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 40% glycerol, 0.2% BSA
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2931097
靶标信息
Transthyretin (TTR), generally called prealbumin, is a plasma protein that plays an important role in physiology such as a transporter of hormone thyroxine and retinal-binding protein. After produced primarily in the liver, TTR is excreted into the plasma. TTR represents a disproportionate fraction (25%) of CSF protein, prompting the suggestion that it is either selectively transported across the blood-CSF barrier or synthesized de novo within the central nervous system. Transthyretin is a constituent found to the neuritic plaques, neurofibrillary tangles, and microangiopathic lesions of senile cerebral amyloid. It has been reported that more than 40 different mutations in the TTR gene associated with amyloid deposition.
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生物信息学
蛋白别名: Amyloidosis I; ATTR; carpal tunnel syndrome 1; epididymis luminal protein 111; pre-albumin; Prealbumin; prealbumin, amyloidosis type I; TBPA; thyroxine-binding prealbumin; Transthyretin
基因别名: CTS; CTS1; HEL111; HsT2651; PALB; TBPA; TTR
UniProt ID: (Human) P02766
Entrez Gene ID: (Human) 7276
