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Trypsin is a 24 kDa enzyme of the serine proteinase family. It is produced in the pancreas as an inactive precursor, trypsinogen, but the active enzyme is located in the gastrointestinal tract where it degrades proteins to large peptides. Trypsin prefers lysine and arginine residues. One of the substrates for trypsin is chymotrypsinogen which is cleaved to produce active chymotrypsin. High levels of immunoreactive trypsin in the bloodstream can indicate pancreatic malfunction and this indicator is used to screene for and diagnose Cystic Fibrosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Anionic trypsin I; Anionic trypsin-I; Beta-trypsin; Cationic trypsinogen; digestive zymogen; MGC120175; MGC149362; nonfunctional trypsin 1; Pretrypsinogen I; Protease Serine 1; Serine protease 1; TCR V beta 4.1; TRYP8; Trypsin I; Trypsin-1; trypsinogen; trypsinogen 1; trypsinogen A
基因别名: PRSS1; TRP1; TRY1; TRY4; TRYP1
UniProt ID: (Human) P07477
Entrez Gene ID: (Human) 5644