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Invitrogen
Tyrosinase Recombinant Rabbit Monoclonal Antibody (JA52-11)
高级验证
This Antibody was verified by Cell treatment to ensure that the antibody binds to the antigen stated.
图: 1 / 8
Tyrosinase Antibody (MA5-32665) in ICC/IF
Immunocytochemical analysis of Tyrosinase in MCF-7 cells using a Tyrosinase Monoclonal antibody (Product # MA5-32665) as seen in red. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
产品信息
MA5-32665
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
JA52-11
抗原
Recombinant protein within Human Tyrosinase aa 1-340
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
TBS, pH 7.4, with 40% Glycerol, 0.05% BSA
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2809942
产品详细信息
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
靶标信息
The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Albino locus protein; LB24-AB; Monophenol monooxygenase; oculocutaneous albinism IA; SK29-AB; Tumor rejection antigen AB; Tyrosinase
基因别名: albino; ATN; c; CMM8; OCA1; OCA1A; OCAIA; SHEP3; skc35; TYR
UniProt ID: (Human) Q8TAK4, (Mouse) P11344
Entrez Gene ID: (Human) 7299, (Mouse) 22173
