Product References
Could the Urease of the Gut Bacterium Proteus mirabilis Play a Role in the Altered Gut-Brain Talk Associated with Parkinson's Disease?
Microorganisms
Grahl MVC,Andrade BDS,Perin APA,Neves GA,Duarte LS,Uberti AF,Hohl KS,Follmer C,Carlini CR
Published figure using Tyrosine Hydroxylase polyclonal antibody (Product # OPA1-04050) in Western Blot
Wed Aug 09 00:00:00 EDT 2023
Inhibition of carnitine palmitoyl-transferase 1 is a potential target in a mouse model of Parkinson's disease.
NPJ Parkinson's disease
Trabjerg MS,Andersen DC,Huntjens P,Mørk K,Warming N,Kullab UB,Skjønnemand MN,Oklinski MK,Oklinski KE,Bolther L,Kroese LJ,Pritchard CEJ,Huijbers IJ,Corthals A,Søndergaard MT,Kjeldal HB,Pedersen CFM,Nieland JDV
OPA1-04050 was used in Western Blotting to confirm that rotenone induces gut dysbiosis in C57Bl/6J and, for the first time, in Park2 knockout mice and show that this dysbiosis is alleviated by the downregulation of the lipid metabolism via CPT1.
Sat Jan 21 00:00:00 EST 2023
Axo-glial interactions between midbrain dopamine neurons and oligodendrocyte lineage cells in the anterior corpus callosum.
Brain structure & function
Caldwell M,Ayo-Jibunoh V,Mendoza JC,Brimblecombe KR,Reynolds LM,Zhu Jiang XY,Alarcon C,Fiore E,N Tomaio J,Phillips GR,Mingote S,Flores C,Casaccia P,Liu J,Cragg SJ,McCloskey DP,Yetnikoff L
OPA1-04050 was used in Immunohistochemistry to provide evidence implicating midbrain dopamine neurons in the innervation of oligodendrocyte lineage cells in the anterior corpus callosum and nearby white matter tracts of male and female adult mice.
Wed Nov 01 00:00:00 EDT 2023
Identifying dominant-negative actions of a dopamine transporter variant in patients with parkinsonism and neuropsychiatric disease.
JCI insight
Herborg F,Jensen KL,Tolstoy S,Arends NV,Posselt LP,Shekar A,Aguilar JI,Lund VK,Erreger K,Rickhag M,Lycas MD,Lonsdale MN,Rahbek-Clemmensen T,Sørensen AT,Newman AH,Løkkegaard A,Kjærulff O,Werge T,Møller LB,Matthies HJ,Galli A,Hjermind LE,Gether U
Published figure using Tyrosine Hydroxylase polyclonal antibody (Product # OPA1-04050) in Western Blot
Wed Sep 22 00:00:00 EDT 2021
Failure of Diphtheria Toxin Model to Induce Parkinson-Like Behavior in Mice.
International journal of molecular sciences
Valek L,Tegeder I
Published figure using Tyrosine Hydroxylase polyclonal antibody (Product # OPA1-04050) in Immunocytochemistry
Tue Aug 31 00:00:00 EDT 2021
Unbiased identification of novel transcription factors in striatal compartmentation and striosome maturation.
eLife
Cirnaru MD,Song S,Tshilenge KT,Corwin C,Mleczko J,Galicia Aguirre C,Benlhabib H,Bendl J,Apontes P,Fullard J,Creus-Muncunill J,Reyahi A,Nik AM,Carlsson P,Roussos P,Mooney SD,Ellerby LM,Ehrlich ME
OPA1-04050 was used in Immunohistochemistry (PFA fixed), Immunohistochemistry to dissect and manipulate the transcription factor networks regulating medium spiny neurone compartmentation and differentiation,.
Tue Oct 05 00:00:00 EDT 2021
Unbiased identification of novel transcription factors in striatal compartmentation and striosome maturation.
eLife
Cirnaru MD,Song S,Tshilenge KT,Corwin C,Mleczko J,Galicia Aguirre C,Benlhabib H,Bendl J,Apontes P,Fullard J,Creus-Muncunill J,Reyahi A,Nik AM,Carlsson P,Roussos P,Mooney SD,Ellerby LM,Ehrlich ME
OPA1-04050 was used in Immunohistochemistry (PFA fixed), Immunohistochemistry to dissect and manipulate the transcription factor networks regulating medium spiny neurone compartmentation and differentiation,.
Tue Oct 05 00:00:00 EDT 2021
Unbiased identification of novel transcription factors in striatal compartmentation and striosome maturation.
eLife
Cirnaru MD,Song S,Tshilenge KT,Corwin C,Mleczko J,Galicia Aguirre C,Benlhabib H,Bendl J,Apontes P,Fullard J,Creus-Muncunill J,Reyahi A,Nik AM,Carlsson P,Roussos P,Mooney SD,Ellerby LM,Ehrlich ME
OPA1-04050 was used in Immunohistochemistry (PFA fixed), Immunohistochemistry to dissect and manipulate the transcription factor networks regulating medium spiny neurone compartmentation and differentiation,.
Tue Oct 05 00:00:00 EDT 2021
Locus coeruleus spiking differently correlates with S1 cortex activity and pupil diameter in a tactile detection task.
eLife
Yang H,Bari BA,Cohen JY,O'Connor DH
OPA1-04050 was used in Immunohistochemistry to stud the relationships between activity in the locus coeruleus (LC), activity in the primary somatosensory cortex (S1), and pupil diameter in mice performing a tactile detection task.
Mon Mar 15 00:00:00 EDT 2021
Locus coeruleus spiking differently correlates with S1 cortex activity and pupil diameter in a tactile detection task.
eLife
Yang H,Bari BA,Cohen JY,O'Connor DH
OPA1-04050 was used in Immunohistochemistry to stud the relationships between activity in the locus coeruleus (LC), activity in the primary somatosensory cortex (S1), and pupil diameter in mice performing a tactile detection task.
Mon Mar 15 00:00:00 EDT 2021
RhoA in tyrosine hydroxylase neurones regulates food intake and body weight via altered sensitivity to peripheral hormones.
Journal of neuroendocrinology
Skov LJ,Ratner C,Hansen NW,Thompson JJ,Egerod KL,Burm H,Dalbøge LS,Hedegaard MA,Brakebusch C,Pers TH,Perrier JF,Holst B
OPA1-04050 was used in Western Blotting to indicate that TH neurones in ARC are important for the regulation of body weight homeostasis and that RhoA is both a central effector in these neurones and important for the development of obesity-induced ghrelin resistance.
Mon Jul 01 00:00:00 EDT 2019
Nicotine aversion is mediated by GABAergic interpeduncular nucleus inputs to laterodorsal tegmentum.
Nature communications
Wolfman SL,Gill DF,Bogdanic F,Long K,Al-Hasani R,McCall JG,Bruchas MR,McGehee DS
OPA1-04050 was used in Immunohistochemistry to show that IPN projections to the laterodorsal tegmentum (LDTg) are GABAergic using optogenetics in tissue slices from mouse brain.
Fri Jul 13 00:00:00 EDT 2018
Systemically administered neuregulin-1β1 rescues nigral dopaminergic neurons via the ErbB4 receptor tyrosine kinase in MPTP mouse models of Parkinson's disease.
Journal of neurochemistry
Depboylu C,Rösler TW,de Andrade A,Oertel WH,Höglinger GU
OPA1-04050 was used in immunohistochemistry - free floating to assess the effects of peripherally administered Nrg1beta1 in a toxin-based mouse model of Parkinson's disease
Fri May 01 00:00:00 EDT 2015
Transcriptional and structural plasticity of tyrosine hydroxylase expressing neurons in both striatum and nucleus accumbens following dopaminergic denervation.
Journal of chemical neuroanatomy
Depboylu C,Klietz M,Maurer L,Oertel WH,Kobayashi K,Weihe E,Höglinger GU,Schäfer MK
OPA1-04050 was used in immunohistochemistry to use transgenic mice to investigate the regulation of tyrosine hydroxylase positive cells following prolonged dopaminergic denervation
Sat Nov 01 00:00:00 EDT 2014
Brain-resident microglia predominate over infiltrating myeloid cells in activation, phagocytosis and interaction with T-lymphocytes in the MPTP mouse model of Parkinson disease.
Experimental neurology
Depboylu C,Stricker S,Ghobril JP,Oertel WH,Priller J,Höglinger GU
OPA1-04050 was used in immunohistochemistry to study the roles of brain-resident microglial cells and infiltrating myeloid cells in a murine model of Parkinson's disease
Sat Dec 01 00:00:00 EST 2012
Changes in serotoninergic and noradrenergic descending pain pathways during painful diabetic neuropathy: the preventive action of IGF1.
Neurobiology of disease
Morgado C,Silva L,Pereira-Terra P,Tavares I
OPA1-04050 was used in immunohistochemistry to investigate the effect of IGF1 on painful diabetic neuropathy
Fri Jul 01 00:00:00 EDT 2011
The L-type channel antagonist isradipine is neuroprotective in a mouse model of Parkinson's disease.
Neurobiology of disease
Ilijic E,Guzman JN,Surmeier DJ
OPA1-04050 was used in immunohistochemistry to investigate the therapeutic effect of L-type channel antagonist isradipine in mouse Parkinson disease model
Mon Aug 01 00:00:00 EDT 2011
Cell type specific sequestration of choline acetyltransferase and tyrosine hydroxylase within Lewy bodies.
Acta neuropathologica
Dugger BN,Dickson DW
OPA1-04050 was used in immunohistochemistry to investigate the distribution of choline acetyltransferase and tyrosine hydroxylase in cholinergic and catecholaminergic neurons
Mon Nov 01 00:00:00 EDT 2010
Incidental Lewy body disease and preclinical Parkinson disease.
Archives of neurology
DelleDonne A,Klos KJ,Fujishiro H,Ahmed Z,Parisi JE,Josephs KA,Frigerio R,Burnett M,Wszolek ZK,Uitti RJ,Ahlskog JE,Dickson DW
OPA1-04050 was used in immunohistochemistry to determine whether incidental Lewy body disease (iLBD) is associated with preclinical Parkinson disease
Fri Aug 01 00:00:00 EDT 2008