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UBAP2L/NICE4 Antibody (A300-534A-T) in WB
Detection of human UBAP2L/NICE-4 by western blot. Samples: Whole cell lysate (50 µg) from HeLa and 293T cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-UBAP2L/NICE-4 antibody A300-534A-M (lot A300-534A-M-1) used for WB at 1:1000. Detection: Chemiluminescence with an exposure time of 3 minutes.
产品信息
A300-534A-T
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Between 1025 and C-term
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
TBS, pH 7.0 to 8.0
内含物
0.09% sodium azide
保存条件
4° C
运输条件
Wet ice
产品详细信息
The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Mouse
靶标信息
NICE4, also known as UBAP2L (Ubiquitin-associated protein 2-like) orKIAA0144, is a 1,087 amino acid protein that is ubiquitously expressed. Phosphorylated upon DNA damage, NICE4 contains one UBA domain and is expressed as 4 isoforms produced by alternative splicing events. The gene that encodes NICE4 maps to human chromosome 1. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes Lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Protein NICE-4; RNA polymerase II degradation factor UBAP2L; ubiquitin associated protein 2-like; Ubiquitin-associated protein 2-like
基因别名: KIAA0144; NICE-4; NICE4; UBAP2L
UniProt ID: (Human) Q14157
Entrez Gene ID: (Human) 9898
