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UBC9 Antibody (MA5-47917) in ICC/IF
Immunocytochemistry/Immunofluorescence analysis of UBC9 in Jurkat cells using UBC9 Recombinant Monoclonal Antibody (Product # MA5-47917). Paraformaldehyde-fixed cells were immobilized on a coverslip and stained with UBC9 Recombinant Monoclonal Antibody at a 1:100 dilution for 1h followed by Alexa Fluor 488 secondary antibody (1:1,000 dilution), showing nuclear staining. Actin filaments were stained with phalloidin (red) and the nuclear stain is DAPI (blue). Panels show from left-right, top-bottom UBC9 Recombinant Monoclonal Antibody, DAPI,... View More
产品信息
MA5-47917
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG, kappa
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
SAIC-36A-9
抗原
Peptide "DHPFGFVAVPTK", derived from the SUMO-conjugating enzyme UBC9, conjugated to KLH.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS
内含物
0.02% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_3074361
产品详细信息
Specificity: Recognises human UBE2I.
靶标信息
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Four alternatively spliced transcript variants encoding the same protein have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: OTTHUMP00000198131; p18; RING-type E3 SUMO transferase UBC9; SUMO-1-protein ligase; SUMO-conjugating enzyme UBC9; SUMO-protein ligase; Ubiquitin carrier protein 9; Ubiquitin carrier protein I; ubiquitin conjugating enzyme 9; ubiquitin conjugating enzyme E2I; Ubiquitin-conjugating enzyme E2 I; ubiquitin-conjugating enzyme E2I (homologous to yeast UBC9); ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast); ubiquitin-conjugating enzyme UbcE2A; ubiquitin-like protein SUMO-1 conjugating enzyme; ubiquitin-protein ligase E2I; Ubiquitin-protein ligase I
基因别名: C358B7.1; P18; UBC9; UBCE9; UBE2I
UniProt ID: (Human) P63279
Entrez Gene ID: (Human) 7329
negative regulation of transcription from RNA polymerase II promoter
cellular protein modification process
ubiquitin-dependent protein catabolic process
chromosome segregation
mitotic nuclear division
viral process
protein sumoylation
positive regulation of I-kappaB kinase/NF-kappaB signaling
negative regulation of transcription, DNA-templated
cell division
global genome nucleotide-excision repair
positive regulation of SUMO transferase activity
