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产品信息
PA5-42827
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide directed towards the N-terminal of human UBD
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2610375
产品详细信息
Peptide sequence: RSKTKVPVQD QVLLLGSKIL KPRRSLSSYG IDKEKTIHLT LKVVKPSDEE
Sequence homology: Cow: 86%; Horse: 86%; Human: 100%; Mouse: 86%; Pig: 86%; Rabbit: 85%; Rat: 86%
靶标信息
UBD qualifies as a marker for an interferon response in hepatocellular carcinoma and colon carcinoma but is not significantly overexpressed in cancers lacking a proinflammatory environment. Immunohistochemical studies demonstrated increased UBD expression in HIV-associated nephropathy and in autosomal dominant polycystic kidney disease.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Diubiquitin; UBD 3; Ubiquitin D; Ubiquitin-like protein FAT10
基因别名: FAT10; GABBR1; UBD; UBD-3
UniProt ID: (Human) O15205
Entrez Gene ID: (Human) 10537
proteolysis
ubiquitin-dependent protein catabolic process
response to organonitrogen compound
protein ubiquitination
protein modification by small protein conjugation
response to interferon-gamma
response to tumor necrosis factor
myeloid dendritic cell differentiation
positive regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
aggresome assembly
