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产品信息
CF806601
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
OTI1D11
抗原
Full length human recombinant protein of human UBE2D2 produced in E.coli.
偶联物
形式
Lyophilized
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 8% trehalose
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
靶标信息
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Two alternatively spliced transcript variants have been found for this gene and they encode distinct isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: (E3-independent) E2 ubiquitin-conjugating enzyme D2; E2 ubiquitin-conjugating enzyme D2; p53-regulated ubiquitin-conjugating enzyme 1; Ubiquitin carrier protein D2; ubiquitin conjugating enzyme E2D 2; Ubiquitin-conjugating enzyme E2 D2; Ubiquitin-conjugating enzyme E2(17)KB 2; Ubiquitin-conjugating enzyme E2-17 kDa 2; ubiquitin-conjugating enzyme E2D 2 (homologous to yeast UBC4/5); Ubiquitin-protein ligase D2
基因别名: E2(17)KB2; PUBC1; UBC4; UBC4/5; UBC5B; UBCH4; UBCH5B; UBE2D2
UniProt ID: (Human) P62837
Entrez Gene ID: (Human) 7322
protein polyubiquitination
stimulatory C-type lectin receptor signaling pathway
cellular protein modification process
ubiquitin-dependent protein catabolic process
protein ubiquitination
TRIF-dependent toll-like receptor signaling pathway
Fc-epsilon receptor signaling pathway
T cell receptor signaling pathway
protein autoubiquitination
regulation of transcription from RNA polymerase II promoter in response to hypoxia
protein K48-linked ubiquitination
