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产品信息
PA5-65767
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2663243
产品详细信息
Immunogen sequence: VLAKWQNSYSI KVVLQELRRL MMSKENMKLP QPPEG
Highest antigen sequence identity to the following orthologs - mouse 97%, rat 100%.
靶标信息
The TMEM189-UEV mRNA is an infrequent but naturally occurring co-transcribed product of the neighboring TMEM189 and UBE2V1 genes. Ubiquitin-conjugating E2 enzyme variant proteins constitute a distinct subfamily within the E2 protein family. They have sequence similarity to other ubiquitin-conjugating enzymes but lack the conserved cysteine residue that is critical for the catalytic activity of E2s. The protein produced by this transcript has UEV1 B domains but the protein is localized to the cytoplasm rather than to the nucleus. The significance of this co-transcribed mRNA and the function of its protein product has not yet been determined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CROC-1; CROC-1UBE2V; CROC1B; DJ1185N5.1.3; DNA-binding protein; KUA-UEV; TRAF6-regulated IKK activator 1 beta Uev1A; ubiquitin conjugating enzyme E2 variant 1; Ubiquitin-conjugating enzyme E2 variant 1; UEV-1; UEV-1CIR1
基因别名: CIR1; CROC-1; CROC1; P/OKcl.19; UBE2V; UBE2V1; UEV-1; UEV1; UEV1A
UniProt ID: (Human) Q13404
Entrez Gene ID: (Human) 7335
protein polyubiquitination
stimulatory C-type lectin receptor signaling pathway
regulation of DNA repair
postreplication repair
regulation of transcription, DNA-templated
cell differentiation
Fc-epsilon receptor signaling pathway
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of transcription, DNA-templated
T cell receptor signaling pathway
positive regulation of NF-kappaB transcription factor activity
nucleotide-binding oligomerization domain containing signaling pathway
protein K63-linked ubiquitination
