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产品信息
H00091544-M01
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
1B10
抗原
UBXN11 (NP_663320.1, 311 a.a. approximately 409 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Immunogen sequence: QGEVIDIRGP IRDTLQNCCP LPARIQEIVV ETPTLAAERE RSQESPNTPA PPLSMLRIKS ENGEQAFLLM MQPDNTIGDV RALLAQARVM DASAFEIFS
靶标信息
This gene encodes a protein with a divergent C-terminal UBX domain. The homologous protein in the rat interacts with members of the Rnd subfamily of Rho GTPases at the cell periphery through its C-terminal region. It also interacts with several heterotrimeric G proteins through their G-alpha subunits and promotes Rho GTPase activation. It is proposed to serve a bidirectional role in the promotion and inhibition of Rho activity through upstream signaling pathways. The 3' coding sequence of this gene contains a polymoprhic region of 24 nt tandem repeats. Several transcripts containing between 1.5 and five repeat units have been reported. Multiple transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Colorectal tumor-associated antigen COA-1; colorectal tumor-associated antigen-1; Socius; UBX domain-containing protein 11; UBX domain-containing protein 5
基因别名: COA-1; PP2243; SOC; SOCI; UBXD5; UBXN11
UniProt ID: (Human) Q63HM6
Entrez Gene ID: (Human) 91544
