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产品信息
BS-20751R-FITC
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide derived from human UCP-2
偶联物
激发/发射光谱
498/517 nm
查看光谱
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
TBS, pH 7.4, with 50% glycerol, 1% BSA
内含物
0.03% ProClin 300
保存条件
-20° C, store in dark
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. UCP2 gene is expressed in many tissues, with the greatest expression in skeletal muscle. UCP2 is thought to play a role in non shivering thermogenesis, obesity and diabetes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Dicarboxylate carrier SLC25A8; Dicarboxylate carrier UCP2; Mitochondrial uncoupling protein 2; Solute carrier family 25 member 8; UCP 2; UCPH; uncoupling protein; uncoupling protein 2 (mitochondrial, proton carrier); Uncoupling protein 2, mitochondrial
基因别名: BMIQ4; SLC25A8; UCP2; UCPH
UniProt ID: (Human) P55851, (Rat) P56500, (Mouse) P70406
Entrez Gene ID: (Human) 7351, (Rat) 54315, (Mouse) 22228
response to superoxide
response to hypoxia
translation
transport
mitochondrial transport
female pregnancy
aging
positive regulation of cell death
proton transport
cellular response to insulin stimulus
cellular response to amino acid starvation
negative regulation of apoptotic process
regulation of mitochondrial membrane potential
negative regulation of insulin secretion involved in cellular response to glucose stimulus
response to fatty acid
cellular response to glucose stimulus
liver regeneration
response to glucose
cellular response to hormone stimulus
