Invitrogen

ULK3 Polyclonal Antibody

产品信息

PA5-59193

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.04-0.4 µg/mL

免疫组化 (IHC)

1:50-1:200

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein corresponding to Human ULK3. Recombinant protein control fragment (Product #RP-89789).

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 40% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

RRID

AB_2649257

产品详细信息

Immunogen sequence: ILKGIRHPHI VQLKDFQWDS DNIYLIMEFC AGGDLSRFIH TRRILPEKVA RVFMQQLASA LQFLHERNIS HLDLKPQNIL LSSLEKPHLK LADFGFAQHM SPWDEKHVLR GSPLYMAPEM VCQRQYDARV DLWSMGVILY GETSFPC

Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 93%.

靶标信息

ULK3 or unc-51-like kinase 3 is a member of the serine/threonine kinase family that is involved in the SHH signaling pathway as a positive regulator of GLI proteins. ULK3 enhances endogenous and over-expressed GLI transcriptional activity in cultured cells and alters its subcellular localization. Furthermore, ULK3 phosphorylates GLI proteins in vitro. ULK3 is widely expressed and its expression is higher in a number of tissues where SHH signaling is known to be active, again suggesting that ULK3 is involved in the SHH pathway as a positive regulator of GLI proteins.

仅用于科研。不用于诊断过程。未经明确授权不得转售。