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UROD Antibody (CF810089) in WB
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY UROD (RC200529, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-UROD. (1. Positive lysates LY424758 (100 µg) and LC424758 (20 µg) can be purchased separately from OriGene.
产品信息
CF810089
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Mouse
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
OTI2G7
抗原
Full length human recombinant protein of human UROD produced in HEK293T cell.
偶联物
Unconjugated
形式
Lyophilized
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 8% trehalose
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
靶标信息
This gene encodes the fifth enzyme of the heme biosynthetic pathway. This enzyme is responsible for catalyzing the conversion of uroporphyrinogen to coproporphyrinogen through the removal of four carboxymethyl side chains. Mutations and deficiency in this enzyme are known to cause familial porphyria cutanea tarda and hepatoerythropoetic porphyria.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: porphyrinogen carboxylase; UPD; URO D; URO-D; Uroporphyrinogen decarboxylase; uroporphyrinogen III decarboxylase
基因别名: AI323803; PCT; porphyrinogen carboxy-lyase; UPD; Uro-d; UROD
UniProt ID: (Human) P06132, (Mouse) P70697
Entrez Gene ID: (Human) 7389, (Mouse) 22275, (Rat) 29421
liver development
protoporphyrinogen IX biosynthetic process
heme biosynthetic process
response to iron ion
response to amine
response to estradiol
response to ethanol
uroporphyrinogen III metabolic process
response to mercury ion
response to methylmercury
response to fungicide
cellular response to arsenic-containing substance
porphyrin-containing compound biosynthetic process
heme metabolic process
response to organic cyclic compound
