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USP2 Antibody (PA5-48091) in ICC/IF
Immunocytochemistry analysis of USP2 in immersion fixed NIH‚3T3 mouse embryonic fibroblast cell line. Samples were incubated in USP2 polyclonal antibody (Product # PA5-48091) using a dilution of 0.3 µg/mL for 3 hours at room temperature followed by NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red) and counterstained with DAPI (blue). Specific staining was localized to cytoplasm.
产品信息
PA5-48091
应用
建议稀释比
已发表文章
产品规格
种属反应
Mouse
已发表种属
Not Applicable
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
E. coli-derived recombinant mouse USP2 isoform 2 Lys47-Met396
偶联物
Unconjugated
形式
Lyophilized
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 5% trehalose
内含物
No Preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2609983
产品详细信息
In direct ELISAs and Western blots, 100% cross-reactivity with recombinant human USP2 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
靶标信息
Ubiquitin is a highly conserved protein involved in the regulation of intracellular protein breakdown, cell cycle regulation, and stress response, is released from degraded proteins by disassembly of the polyubiquitin chains. The disassembly process is mediated by ubiquitin-specific proteases (USPs).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: 41 kDa ubiquitin-specific protease; Deubiquitinating enzyme 2; Ubiquitin carboxyl-terminal hydrolase 2; ubiquitin specific protease 2; Ubiquitin thioesterase 2; ubiquitin thiolesterase 2; Ubiquitin-specific-processing protease 2
基因别名: B930035K21Rik; MNCb-0190; Ubp41; Usp2
UniProt ID: (Mouse) O88623
Entrez Gene ID: (Mouse) 53376
cysteine-type endopeptidase activity
thiol-dependent ubiquitin-specific protease activity
peptidase activity
cysteine-type peptidase activity
hydrolase activity
cyclin binding
ubiquitin protein ligase binding
thiol-dependent ubiquitinyl hydrolase activity
identical protein binding
metal ion binding
cysteine protease
negative regulation of transcription from RNA polymerase II promoter
regulation of transcription, DNA-templated
proteolysis
ubiquitin-dependent protein catabolic process
cell cycle
muscle organ development
protein deubiquitination
circadian regulation of gene expression
entrainment of circadian clock by photoperiod
proteasome-mediated ubiquitin-dependent protein catabolic process
locomotor rhythm
positive regulation of mitotic cell cycle
rhythmic process
circadian behavior
negative regulation of skeletal muscle tissue development
positive regulation of skeletal muscle tissue development
protein stabilization
regulation of proteasomal protein catabolic process
