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May be required for maintaining multiple types of adult stem cells. May function as a transcriptional repressor by continually deubiquiting histone H2B at the promoters of genes critical for cellular differentiation, thereby preventing histone H3 'Lys-4' trimethylation (H3K4).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Deubiquitinating enzyme 36; Ubiquitin carboxyl-terminal hydrolase 36; ubiquitin specific protease 36; Ubiquitin thioesterase 36; Ubiquitin-specific-processing protease 36
基因别名: DUB1; KIAA1453; USP36
UniProt ID: (Human) Q9P275
Entrez Gene ID: (Human) 57602, (Dog) 483344