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产品信息
PA5-27869
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 528 and 872 of Human USP4
偶联物
Unconjugated
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 1% BSA, 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2545345
产品详细信息
Recommended positive controls: U87-MG, MCF-7.
Predicted reactivity: Mouse (86%), Rat (85%), Pig (90%), Bovine (89%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
The protein encoded by this gene is a protease that deubiquitinates target proteins such as ADORA2A and TRIM21. The encoded protein shuttles between the nucleus and cytoplasm and is involved in maintaining operational fidelity in the endoplasmic reticulum. Three transcript variants encoding different isoforms have been found for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Deubiquitinating enzyme 4; ubiquitin carboxyl-terminal esterase 4; Ubiquitin carboxyl-terminal hydrolase 4; ubiquitin specific peptidase 4 (proto-oncogene); ubiquitin specific protease 4 (proto-oncogene); Ubiquitin thioesterase 4; ubiquitin thiolesterase 4; ubiquitin-specific processing protease 4; Ubiquitin-specific-processing protease 4; Ubiquitous nuclear protein; Ubiquitous nuclear protein homolog
基因别名: F730026I20Rik; mKIAA4155; UNP; UNPH; USP4
UniProt ID: (Human) Q13107, (Mouse) P35123
Entrez Gene ID: (Human) 7375, (Mouse) 22258
thiol-dependent ubiquitin-specific protease activity
protein binding
adenosine receptor binding
identical protein binding
metal ion binding
cysteine-type endopeptidase activity
peptidase activity
cysteine-type peptidase activity
hydrolase activity
thiol-dependent ubiquitinyl hydrolase activity
cysteine protease
spliceosomal tri-snRNP complex assembly
ubiquitin-dependent protein catabolic process
protein deubiquitination
negative regulation of protein ubiquitination
regulation of protein stability
protein localization to cell surface
proteolysis
proteasome-mediated ubiquitin-dependent protein catabolic process
regulation of proteasomal protein catabolic process
