Product References
Selenoprotein P deficiency protects against immobilization-induced muscle atrophy by suppressing atrophy-related E3 ubiquitin ligases.
American journal of physiology. Endocrinology and metabolism
Abuduwaili H,Kamoshita K,Ishii KA,Takahashi K,Abuduyimiti T,Qifang L,Isobe Y,Goto H,Nakano Y,Takeshita Y,Takayama H,Harada K,Takamura T
Thu Jun 01 00:00:00 EDT 2023
NPM1 promotes nasopharyngeal carcinoma metastasis and stemness by recruiting Mdm2 to induce the ubiquitination-mediated degradation of p53.
American journal of cancer research
Hu L,Gong P,Zhou N,Wang S,He C,Zhou Y,Li Q,Zhao X,Peng H
Mon Jun 12 00:00:00 EDT 2023
1,25(OH)2 D3 induced vitamin D receptor signaling negatively regulates endoplasmic reticulum-associated degradation (ERAD) and androgen receptor signaling in human prostate cancer cells.
Cellular signalling
Erzurumlu Y,Aydogdu E,Dogan HK,Catakli D,Muhammed MT,Buyuksandic B
Wed Mar 01 00:00:00 EST 2023
PD-L1 upregulation promotes drug-induced pulmonary fibrosis by inhibiting vimentin degradation.
Pharmacological research
Li Q,Deng MS,Wang RT,Luo H,Luo YY,Zhang DD,Chen KJ,Cao XF,Yang GM,Zhao TM,Xu B,Xu CX,Wang JM
Sun Jan 01 00:00:00 EST 2023
Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.
Cell death and differentiation
Cao YF,Xie L,Tong BB,Chu MY,Shi WQ,Li X,He JZ,Wang SH,Wu ZY,Deng DX,Zheng YQ,Li ZM,Xu XE,Liao LD,Cheng YW,Li LY,Xu LY,Li EM
Wed Feb 01 00:00:00 EST 2023
NLRP3 Regulates Mandibular Healing through Interaction with UCHL5 in MSCs.
International journal of biological sciences
Zhao W,Cao Y,Chen Y,Chen Y,Wang T,Li L,Xu Y,Yuan H,Wang H,Wang R,Sun W
Wed Feb 15 00:00:00 EST 2023
NLRP3 Regulates Mandibular Healing through Interaction with UCHL5 in MSCs.
International journal of biological sciences
Zhao W,Cao Y,Chen Y,Chen Y,Wang T,Li L,Xu Y,Yuan H,Wang H,Wang R,Sun W
Wed Feb 15 00:00:00 EST 2023
RBX1 regulates PKM alternative splicing to facilitate anaplastic thyroid carcinoma metastasis and aerobic glycolysis by destroying the SMAR1/HDAC6 complex.
Cell & bioscience
Xu D,Yu J,Yang Y,Du Y,Lu H,Zhang S,Feng Q,Yu Y,Hao L,Shao J,Chen L
Tue Feb 21 00:00:00 EST 2023
RSL1D1 knockdown induces ferroptosis and mediates ferrous iron accumulation in senescent cells by inhibiting FTH1 mRNA stability.
Carcinogenesis
Jin Y,Zhao L,Wang S,Zhang X,Quan J,Lin Z,Piao J
Fri May 26 00:00:00 EDT 2023
Wnt/β-Catenin Promotes the Osteoblastic Potential of BMP9 Through Down-Regulating Cyp26b1 in Mesenchymal Stem Cells.
Tissue engineering and regenerative medicine
Yao XT,Li PP,Liu J,Yang YY,Luo ZL,Jiang HT,He WG,Luo HH,Deng YX,He BC
Tue Aug 01 00:00:00 EDT 2023
The oncogenic role of NF1 in gallbladder cancer through regulation of YAP1 stability by direct interaction with YAP1.
Journal of translational medicine
Zhang L,Jiang L,Zeng L,Jin Z,Dong X,Zhang Y,Chen L,Shu Y,Liu Y,Huang Y
Fri May 05 00:00:00 EDT 2023
Albumosomes formed by cytoplasmic pre-folding albumin maintain mitochondrial homeostasis and inhibit nonalcoholic fatty liver disease.
Signal transduction and targeted therapy
Ma B,Ju A,Zhang S,An Q,Xu S,Liu J,Yu L,Fu Y,Luo Y
Fri Jun 16 00:00:00 EDT 2023
Polydopamine Nanoparticles Targeting Ferroptosis Mitigate Intervertebral Disc Degeneration Via Reactive Oxygen Species Depletion, Iron Ions Chelation, and GPX4 Ubiquitination Suppression.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Yang X,Chen Y,Guo J,Li J,Zhang P,Yang H,Rong K,Zhou T,Fu J,Zhao J
Mon May 01 00:00:00 EDT 2023
Deubiquitinating enzyme USP11 promotes renal tubular cell senescence and fibrosis via inhibiting the ubiquitin degradation of TGF-β receptor II.
Acta pharmacologica Sinica
Ni JY,Wang X,Xie HY,Yang NH,Li JY,Sun XA,Guo HJ,Zhou L,Zhang W,Liu J,Lu LM
Wed Mar 01 00:00:00 EST 2023
Intrahippocampal injection of IL-1β upregulates Siah1-mediated degradation of synaptophysin by activation of the ERK signaling in male rat.
Journal of neuroscience research
Zhou Q,Lin L,Li H,Li Y,Liu N,Wang H,Jiang S,Li Q,Chen Z,Lin Y,Jin H,Deng Y
Thu Jun 01 00:00:00 EDT 2023
Intrahippocampal injection of IL-1β upregulates Siah1-mediated degradation of synaptophysin by activation of the ERK signaling in male rat.
Journal of neuroscience research
Zhou Q,Lin L,Li H,Li Y,Liu N,Wang H,Jiang S,Li Q,Chen Z,Lin Y,Jin H,Deng Y
Thu Jun 01 00:00:00 EDT 2023
Ring domains are essential for GATOR2-dependent mTORC1 activation.
Molecular cell
Jiang C,Dai X,He S,Zhou H,Fang L,Guo J,Liu S,Zhang T,Pan W,Yu H,Fu T,Li D,Inuzuka H,Wang P,Xiao J,Wei W
Thu Jan 05 00:00:00 EST 2023
SENP3 and USP7 regulate Polycomb-rixosome interactions and silencing functions.
Cell reports
Zhou H,Feng W,Yu J,Shafiq TA,Paulo JA,Zhang J,Luo Z,Gygi SP,Moazed D
Tue Apr 25 00:00:00 EDT 2023
SENP3 and USP7 regulate Polycomb-rixosome interactions and silencing functions.
Cell reports
Zhou H,Feng W,Yu J,Shafiq TA,Paulo JA,Zhang J,Luo Z,Gygi SP,Moazed D
Tue Apr 25 00:00:00 EDT 2023
Multi-proteomic Analysis Revealed Distinct Protein Profiles in Cerebrospinal Fluid of Patients Between Anti-NMDAR Encephalitis NORSE and Cryptogenic NORSE.
Molecular neurobiology
Wang D,Wu Y,Pan Y,Wang S,Liu G,Gao Y,Xu K
Sun Jan 01 00:00:00 EST 2023
Rho A/ROCK1 signaling-mediated metabolic reprogramming of valvular interstitial cells toward Warburg effect accelerates aortic valve calcification via AMPK/RUNX2 axis.
Cell death & disease
Liu H,Yin H,Wang Z,Yuan Q,Xu F,Chen Y,Li C
Sat Feb 11 00:00:00 EST 2023
Ribosome Biogenesis Regulator 1 Homolog (RRS1) Promotes Cisplatin Resistance by Regulating AEG-1 Abundance in Breast Cancer Cells.
Molecules (Basel, Switzerland)
Song J,Peng C,Wang R,Hua Y,Wu Q,Deng L,Cao Y,Zhang L,Hou L
Sat Mar 25 00:00:00 EDT 2023
Radiation induces IRAK1 expression to promote radioresistance by suppressing autophagic cell death via decreasing the ubiquitination of PRDX1 in glioma cells.
Cell death & disease
Li J,Sun Y,Zhao X,Ma Y,Xie Y,Liu S,Hui B,Shi X,Sun X,Zhang X
Sat Apr 08 00:00:00 EDT 2023
De novo lipogenesis fuels adipocyte autophagosome and lysosome membrane dynamics.
Nature communications
Rowland LA,Guilherme A,Henriques F,DiMarzio C,Munroe S,Wetoska N,Kelly M,Reddig K,Hendricks G,Pan M,Han X,Ilkayeva OR,Newgard CB,Czech MP
Mon Mar 13 00:00:00 EDT 2023
Neocryptotanshinone protects against myocardial ischemia-reperfusion injury by promoting autolysosome degradation of protein aggregates via the ERK1/2-Nrf2-LAMP2 pathway.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Yang Y,Shao M,Yao J,Yang S,Cheng W,Ma L,Li W,Cao J,Zhang Y,Hu Y,Li C,Wang Y,Wang W
Wed Feb 01 00:00:00 EST 2023
CEBPB upregulates P4HA2 to promote the malignant biological behavior in IDH1 wildtype glioma.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Wang S,Wu J,Zhao W,Li M,Li S
Sat Apr 01 00:00:00 EDT 2023
MYB30 integrates light signals with antioxidant biosynthesis to regulate plant responses during postsubmergence recovery.
The New phytologist
Xie LJ,Wang JH,Liu HS,Yuan LB,Tan YF,Tan WJ,Zhou Y,Chen QF,Qi H,Li JF,Chen YQ,Qiu RL,Chen MX,Xiao S
Wed Mar 01 00:00:00 EST 2023
Phosphorylation by IKKβ Promotes the Degradation of HMGCL via NEDD4 in Lung Cancer.
International journal of biological sciences
Zhong C,Xiong G,Yang H,Du X,Du J,Yao F,Fang W,Deng Y
Tue Mar 21 00:00:00 EDT 2023
Polyphyllin D punctures hypertrophic lysosomes to reverse drug resistance of hepatocellular carcinoma by targeting acid sphingomyelinase.
Molecular therapy : the journal of the American Society of Gene Therapy
Wang Y,Chen YY,Gao GB,Zheng YH,Yu NN,Ouyang L,Gao X,Li N,Wen SY,Huang S,Zhao Q,Liu L,Cao M,Zhang S,Zhang J,He QY
Wed Jul 05 00:00:00 EDT 2023
Proximity labeling reveals OTUD3 as a DNA-binding deubiquitinase of cGAS.
Cell reports
Lyu H,Sun L,Guan Z,Li J,Yin C,Zhang Y,Jiang H
Tue Apr 25 00:00:00 EDT 2023
Fzr regulates silk gland growth by promoting endoreplication and protein synthesis in the silkworm.
PLoS genetics
Qian W,Li H,Zhang X,Tang Y,Yuan D,Huang Z,Cheng D
Sun Jan 01 00:00:00 EST 2023
Cathepsin K promotes the proliferation of hepatocellular carcinoma cells through induction of SIAH1 ubiquitination and degradation.
iScience
Zhang C,Liu Z,Wang X,Zhang B,Cui L,Hu Q,Hu B,Cao K,Shan W,Shi H,Wang R
Fri Jun 16 00:00:00 EDT 2023
TRIM21 ubiquitylates GPX4 and promotes ferroptosis to aggravate ischemia/reperfusion-induced acute kidney injury.
Life sciences
Sun X,Huang N,Li P,Dong X,Yang J,Zhang X,Zong WX,Gao S,Xin H
Mon May 15 00:00:00 EDT 2023
Combinations of ivermectin with proteasome inhibitors induce synergistic lethality in multiple myeloma.
Cancer letters
Luo H,Feng Y,Wang F,Lin Z,Huang J,Li Q,Wang X,Liu X,Zhai X,Gao Q,Li L,Zhang Y,Wen J,Zhang L,Niu T,Zheng Y
Sat Jul 01 00:00:00 EDT 2023
Triiodothyronine positively regulates endoplasmic reticulum-associated degradation (ERAD) and promotes androgenic signaling in androgen-dependent prostate cancer cells.
Cellular signalling
Erzurumlu Y,Muhammed MT
Fri Sep 01 00:00:00 EDT 2023
The Valsa Mali effector Vm1G-1794 protects the aggregated MdEF-Tu from autophagic degradation to promote infection in apple.
Autophagy
Che R,Liu C,Wang Q,Tu W,Wang P,Li C,Gong X,Mao K,Feng H,Huang L,Li P,Ma F
Thu Jun 01 00:00:00 EDT 2023
S1PR1 serves as a viable drug target against pulmonary fibrosis by increasing the integrity of the endothelial barrier of the lung.
Acta pharmaceutica Sinica. B
Hao M,Fu R,Tai J,Tian Z,Yuan X,Chen Y,Wang M,Jiang H,Ji M,Lai F,Xue N,Bai L,Zhu Y,Lv X,Chen X,Jin J
Wed Mar 01 00:00:00 EST 2023
OTUB1 Catalytic-Independently Deubiquitinates TGFBI and Mediates the Angiogenesis in Infantile Hemangioma by Regulating Glycolysis.
Arteriosclerosis, thrombosis, and vascular biology
Li M,Wang X,Yang E,Li Y,Geng Y,Chen Z,Huang S,Zhang D,Wu H
Mon May 01 00:00:00 EDT 2023
BDE209-promoted Dio2 degradation in H4 glioma cells through the autophagy pathway, resulting in hypothyroidism and leading to neurotoxicity.
Toxicology
Liu M,Yu Z,Yang F,Zhao Z,Zhou M,Wang C,Zhang B,Liang G,Liu X,Shao J
Tue Aug 01 00:00:00 EDT 2023
Dexamethasone-stimulated glucocorticoid receptor signaling positively regulates the endoplasmic reticulum-associated degradation (ERAD) mechanism in hepatocellular carcinoma cells.
Steroids
Erzurumlu Y,Dogan HK,Cataklı D
Sat Jul 01 00:00:00 EDT 2023
UBE2E2 enhances Snail-mediated epithelial-mesenchymal transition and Nrf2-mediated antioxidant activity in ovarian cancer.
Cell death & disease
Hong X,Ma N,Li D,Zhang M,Dong W,Huang J,Ci X,Zhang S
Fri Feb 10 00:00:00 EST 2023
HDAC4 mediated LHPP deacetylation enhances its destabilization and promotes the proliferation and metastasis of nasopharyngeal carcinoma.
Cancer letters
Sun X,Zhang K,Peng X,Zhou P,Qu C,Yang L,Shen L
Sun May 28 00:00:00 EDT 2023
A novel variant in the FBP1 gene causes fructose-1,6-bisphosphatase deficiency through increased ubiquitination.
Archives of biochemistry and biophysics
Liang X,Liu X,Li W,Zhang L,Zhang B,Lai G,Zhao Y
Sat Jul 01 00:00:00 EDT 2023
SPY1 inhibits neuronal ferroptosis in amyotrophic lateral sclerosis by reducing lipid peroxidation through regulation of GCH1 and TFR1.
Cell death and differentiation
Wang D,Liang W,Huo D,Wang H,Wang Y,Cong C,Zhang C,Yan S,Gao M,Su X,Tan X,Zhang W,Han L,Zhang D,Feng H
Wed Feb 01 00:00:00 EST 2023
CLSTN3β enforces adipocyte multilocularity to facilitate lipid utilization.
Nature
Qian K,Tol MJ,Wu J,Uchiyama LF,Xiao X,Cui L,Bedard AH,Weston TA,Rajendran PS,Vergnes L,Shimanaka Y,Yin Y,Jami-Alahmadi Y,Cohn W,Bajar BT,Lin CH,Jin B,DeNardo LA,Black DL,Whitelegge JP,Wohlschlegel JA,Reue K,Shivkumar K,Chen FJ,Young SG,Li P,Tontonoz P
Sun Jan 01 00:00:00 EST 2023
Potent carotenoid astaxanthin expands the anti-cancer activity of cisplatin in human prostate cancer cells.
Journal of natural medicines
Erzurumlu Y,Catakli D,Dogan HK
Thu Jun 01 00:00:00 EDT 2023
UCHL3 promotes cervical cancer development and metastasis by stabilizing NRF2 via deubiquitination.
Biochemical and biophysical research communications
Zhang Y,Liu JB,Liu J,Liu M,Liu HL,Zhang J
Sun Jan 22 00:00:00 EST 2023
UCHL3 promotes cervical cancer development and metastasis by stabilizing NRF2 via deubiquitination.
Biochemical and biophysical research communications
Zhang Y,Liu JB,Liu J,Liu M,Liu HL,Zhang J
Sun Jan 22 00:00:00 EST 2023
MDM2 upregulation induces mitophagy deficiency via Mic60 ubiquitination in fetal microglial inflammation and consequently neuronal DNA damage caused by exposure to ZnO-NPs during pregnancy.
Journal of hazardous materials
Zhang Y,Zhang Y,Lei Y,Wu J,Kang Y,Zheng S,Shao L
Tue Sep 05 00:00:00 EDT 2023
MDM2 upregulation induces mitophagy deficiency via Mic60 ubiquitination in fetal microglial inflammation and consequently neuronal DNA damage caused by exposure to ZnO-NPs during pregnancy.
Journal of hazardous materials
Zhang Y,Zhang Y,Lei Y,Wu J,Kang Y,Zheng S,Shao L
Tue Sep 05 00:00:00 EDT 2023
Downregulation of Histone H4 Lysine 16 Acetylation Ameliorates Autophagic Flux by Resuming Lysosomal Functions in Ischemic Neurons.
ACS chemical neuroscience
Yuyuan L,Xiaoming Z,Lei Z,Tao G,Hongyun H,Yihao D
Wed May 17 00:00:00 EDT 2023
Bone-targeted bortezomib increases bone formation within Calvarial trans-sutural distraction osteogenesis.
Bone
Chen H,Cai G,Ruan X,Lu Y,Li G,Chen Z,Guan Z,Zhang H,Sun W,Wang H
Sat Apr 01 00:00:00 EDT 2023
SYTL2 promotes metastasis of prostate cancer cells by enhancing FSCN1-mediated pseudopodia formation and invasion.
Journal of translational medicine
Li Z,Tao Y,Gao Z,Peng S,Lai Y,Li K,Chen X,Huang H
Fri May 05 00:00:00 EDT 2023
Hepatocyte CD36 modulates UBQLN1-mediated proteasomal degradation of autophagic SNARE proteins contributing to septic liver injury.
Autophagy
Li Y,Xu J,Chen W,Wang X,Zhao Z,Li Y,Zhang L,Jiao J,Yang Q,Ding Q,Yang P,Wei L,Chen Y,Chen Y,Ruan XZ,Zhao L
Fri Sep 01 00:00:00 EDT 2023
E3 ligase MAEA-mediated ubiquitination and degradation of PHD3 promotes glioblastoma progression.
Oncogene
Zhou P,Peng X,Tang S,Zhang K,Tan Z,Li D,Shen L,Peng J,Yang L
Sat Apr 01 00:00:00 EDT 2023
E3 ligase MAEA-mediated ubiquitination and degradation of PHD3 promotes glioblastoma progression.
Oncogene
Zhou P,Peng X,Tang S,Zhang K,Tan Z,Li D,Shen L,Peng J,Yang L
Sat Apr 01 00:00:00 EDT 2023
Progesterone regulates the endoplasmic reticulum-associated degradation and Unfolded Protein Response axis by mimicking the androgenic stimulation in prostate cancer cells.
Molecular biology reports
Erzurumlu Y,Dogan HK,Catakli D
Wed Feb 01 00:00:00 EST 2023
mascRNA alleviates STING-TBK1 signaling-mediated immune response through promoting ubiquitination of STING.
Molecular immunology
Hu Y,Li X,Wang D,Mao X
Wed Feb 01 00:00:00 EST 2023
ASPM promotes migration and invasion of anaplastic thyroid carcinoma by stabilizing KIF11.
Cell biology international
Fang Q,Li Q,Qi Y,Pan Z,Feng T,Xin W
Sat Jul 01 00:00:00 EDT 2023
Kaempferol inhibits non-homologous end joining repair via regulating Ku80 stability in glioma cancer.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Chen M,Zhao E,Li M,Xu M,Hao S,Gao Y,Wu X,Li X,Yu Y,Yu Z,Yin Y
Tue Jul 25 00:00:00 EDT 2023
miR-137-LAPTM4B regulates cytoskeleton organization and cancer metastasis via the RhoA-LIMK-Cofilin pathway in osteosarcoma.
Oncogenesis
Yan R,Liu D,Wang J,Liu M,Guo H,Bai J,Yang S,Chang J,Yao Z,Yang Z,Blom T,Zhou K
Sat May 06 00:00:00 EDT 2023
Molecular functions of the double-sided and inverted ubiquitin-interacting motif found in Xenopus tropicalis cryptochrome 6.
Development, growth & differentiation
Okano K,Otsuka H,Nakagawa M,Okano T
Mon May 01 00:00:00 EDT 2023
Antitumoral effects of Bortezomib in malignant mesothelioma: evidence of mild endoplasmic reticulum stress in vitro and activation of T cell response in vivo.
Biology direct
Benvenuto M,Angiolini V,Focaccetti C,Nardozi D,Palumbo C,Carrano R,Rufini A,Bei R,Miele MT,Mancini P,Barillari G,Cirone M,Ferretti E,Tundo GR,Mutti L,Masuelli L,Bei R
Mon Apr 17 00:00:00 EDT 2023
O-GlcNAcylation enhances Reticulon 2 protein stability and its promotive effects on gastric cancer progression.
Cellular signalling
Wang G,Xu Z,Sun J,Liu B,Ruan Y,Gu J,Song S
Tue Aug 01 00:00:00 EDT 2023
PPARγ Acetylation Orchestrates Adipose Plasticity and Metabolic Rhythms.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
He Y,B'nai Taub A,Yu L,Yao Y,Zhang R,Zahr T,Aaron N,LeSauter J,Fan L,Liu L,Tazebay R,Que J,Pajvani U,Wang L,Silver R,Qiang L
Sun Jan 01 00:00:00 EST 2023
Hepatic RACK1 deficiency protects against fulminant hepatitis through myeloid-derived suppressor cells.
Theranostics
Liu G,Wang Q,Deng L,Huang X,Yang G,Cheng Q,Guo T,Guo L,Niu C,Yang X,Dong J,Zhang J
Thu Apr 21 00:00:00 EDT 2022
4EBP1 senses extracellular glucose deprivation and initiates cell death signaling in lung cancer.
Cell death & disease
Wang Y,Lei J,Zhang S,Wang X,Jin J,Liu Y,Gan M,Yuan Y,Sun L,Li X,Han T,Wang JB
Tue Dec 27 00:00:00 EST 2022
IKZF1 selectively enhances homologous recombination repair by interacting with CtIP and USP7 in multiple myeloma.
International journal of biological sciences
Liu M,Zhang Y,Wu Y,Jin J,Cao Y,Fang Z,Geng L,Yang L,Yu M,Bu Z,Ji Y,Shan H,Zou Z,Liu L,Wang Y,Zhang Y,Tong Y,Xu H,Lei H,Liu W,Gao F,Wu Y
Thu Apr 14 00:00:00 EDT 2022
LINC01194 recruits NUMA1 to promote ubiquitination of RYR2 to enhance malignant progression in triple-negative breast cancer.
Cancer letters
Zhai D,Zhang M,Li Y,Bi J,Kuang X,Shan Z,Shao N,Lin Y
Wed Sep 28 00:00:00 EDT 2022
Phosphorylation-Induced Ubiquitination and Degradation of PXR through CDK2-TRIM21 Axis.
Cells
Qin M,Xin Y,Bian Y,Yang X,Xi T,Xiong J
Thu Jan 13 00:00:00 EST 2022
Mistargeting of aggregation prone mitochondrial proteins activates a nucleus-mediated posttranscriptional quality control pathway in trypanosomes.
Nature communications
Dewar CE,Oeljeklaus S,Mani J,Mühlhäuser WWD,von Känel C,Zimmermann J,Ochsenreiter T,Warscheid B,Schneider A
Thu Jun 02 00:00:00 EDT 2022
Bortezomib prodrug catalytic nanoreactor for chemo/chemodynamic therapy and macrophage re-education.
Journal of controlled release : official journal of the Controlled Release Society
Huang Y,Guan Z,Ren L,Luo Y,Chen M,Sun Y,He Y,Zeng Z,Dai X,Jiang J,Huang Z,Zhao C
Sat Oct 01 00:00:00 EDT 2022
A novel protein encoded by circHNRNPU promotes multiple myeloma progression by regulating the bone marrow microenvironment and alternative splicing.
Journal of experimental & clinical cancer research : CR
Tang X,Deng Z,Ding P,Qiang W,Lu Y,Gao S,Hu Y,Yang Y,Du J,Gu C
Tue Mar 08 00:00:00 EST 2022
MICALL2 as a substrate of ubiquitinase TRIM21 regulates tumorigenesis of colorectal cancer.
Cell communication and signaling : CCS
Wen P,Wang H,Li Y,Sui X,Hou Z,Guo X,Xue W,Liu D,Wang Y,Gao J
Fri Oct 28 00:00:00 EDT 2022
Rho family GTPase 1 (RND1), a novel regulator of p53, enhances ferroptosis in glioblastoma.
Cell & bioscience
Sun Q,Xu Y,Yuan F,Qi Y,Wang Y,Chen Q,Liu B
Tue May 03 00:00:00 EDT 2022
Mitochondrial STAT3 exacerbates LPS-induced sepsis by driving CPT1a-mediated fatty acid oxidation.
Theranostics
Li R,Li X,Zhao J,Meng F,Yao C,Bao E,Sun N,Chen X,Cheng W,Hua H,Li X,Wang B,Wang H,Pan X,You H,Yang J,Ikezoe T
Thu Mar 10 00:00:00 EST 2022
Cullin-associated and neddylation-dissociated 1 protein (CAND1) governs cardiac hypertrophy and heart failure partially through regulating calcineurin degradation.
Pharmacological research
Li X,Zhang Y,Zhao Y,Zhou Y,Han Q,Yang Y,Zhang L,Shi L,Jin X,Zhang R,Gao H,Xue G,Li D,Zhang ZR,Lu Y,Yang B,Pan Z
Mon Aug 01 00:00:00 EDT 2022
Ubiquitinated gasdermin D mediates arsenic-induced pyroptosis and hepatic insulin resistance in rat liver.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Zhu Y,Zhang J,Yao X,Qiu T,Jiang L,Wang N,Shi Y,Wu C,Yuan W,Yang G,Liu X,Bai J,Men L,Sun X
Tue Feb 01 00:00:00 EST 2022
Gamma frequency light flicker regulates amyloid precursor protein trafficking for reducing β-amyloid load in Alzheimer's disease model.
Aging cell
Shen Q,Wu X,Zhang Z,Zhang D,Yang S,Xing D
Tue Mar 01 00:00:00 EST 2022
Pyrogallol enhances therapeutic effect of human umbilical cord mesenchymal stem cells against LPS-mediated inflammation and lung injury via activation of Nrf2/HO-1 signaling.
Free radical biology & medicine
Zhang Y,Yang S,Qiu Z,Huang L,Huang L,Liang Y,Liu X,Wang M,Zhou B
Sat Oct 01 00:00:00 EDT 2022
lncRNA SNHG26 promoted the growth, metastasis, and cisplatin resistance of tongue squamous cell carcinoma through PGK1/Akt/mTOR signal pathway.
Molecular therapy oncolytics
Jiang Q,Wang Z,Qi Q,Li J,Xin Y,Qiu J
Thu Mar 17 00:00:00 EDT 2022
SPOCK1 promotes metastasis in pancreatic cancer via NF-κB-dependent epithelial-mesenchymal transition by interacting with IκB-α.
Cellular oncology (Dordrecht)
Cui X,Wang Y,Lan W,Wang S,Cui Y,Zhang X,Lin Z,Piao J
Tue Feb 01 00:00:00 EST 2022
Cyclo(-Phe-Phe) alleviates chick embryo liver injury via activating the Nrf2 pathway.
Food & function
Zhang QY,Han SC,Huang RP,Jiang MY,Yan CY,Li XY,Zhan YJ,Li XM,Li YF,Kurihara H,Tan RR,Li WX,He RR
Mon Jul 04 00:00:00 EDT 2022
Pantothenate Kinase 1 Inhibits the Progression of Hepatocellular Carcinoma by Negatively Regulating Wnt/β-catenin Signaling.
International journal of biological sciences
Zi Y,Gao J,Wang C,Guan Y,Li L,Ren X,Zhu L,Mu Y,Chen SH,Zeng Z,Cao Z,Rong Z,Chen P,Zhang X,Chen T,Xin H,Li X,Li Z,Sun L,Deng Y,Li N,Nie Y
Fri Apr 15 00:00:00 EDT 2022
Golgi Phosphoprotein 3 Confers Radioresistance via Stabilizing EGFR in Lung Adenocarcinoma.
International journal of radiation oncology, biology, physics
Chen G,Kong P,Yang M,Hu W,Prise KM,Yu KN,Cui S,Qin F,Meng G,Almahi WA,Nie L,Han W
Fri Apr 01 00:00:00 EDT 2022
Deacetylation of Glutaminase by HDAC4 contributes to Lung Cancer Tumorigenesis.
International journal of biological sciences
Wang T,Lu Z,Han T,Wang Y,Gan M,Wang JB
Mon Jul 25 00:00:00 EDT 2022
The dual role of p62 in ferroptosis of glioblastoma according to p53 status.
Cell & bioscience
Yuan F,Sun Q,Zhang S,Ye L,Xu Y,Deng G,Xu Z,Zhang S,Liu B,Chen Q
Fri Feb 25 00:00:00 EST 2022
circFAM120B functions as a tumor suppressor in esophageal squamous cell carcinoma via the miR-661/PPM1L axis and the PKR/p38 MAPK/EMT pathway.
Cell death & disease
Song H,Tian D,Sun J,Mao X,Kong W,Xu D,Ji Y,Qiu B,Zhan M,Wang J
Mon Apr 18 00:00:00 EDT 2022
A small molecule inhibitor of caspase-1 inhibits NLRP3 inflammasome activation and pyroptosis to alleviate gouty inflammation.
Immunology letters
Cao DY,Zhang ZH,Li RZ,Shi XK,Xi RY,Zhang GL,Li F,Wang F
Fri Apr 01 00:00:00 EDT 2022
Honokiol Inhibits HIF-1α-Mediated Glycolysis to Halt Breast Cancer Growth.
Frontiers in pharmacology
Yi X,Qi M,Huang M,Zhou S,Xiong J
Fri Apr 01 00:00:00 EDT 2022
Choline-induced SLC5A7 impairs colorectal cancer growth by stabilizing p53 protein.
Cancer letters
Yin Y,Jiang Z,Fu J,Li Y,Fang C,Yin X,Chen Y,Chen N,Li J,Ji Y,Su X,Qiu M,Huang W,Zhang B,Deng H,Dai L
Fri Jan 28 00:00:00 EST 2022
14-3-3 proteins contribute to autophagy by modulating SINAT-mediated degradation of ATG13.
The Plant cell
Qi H,Lei X,Wang Y,Yu S,Liu T,Zhou SK,Chen JY,Chen QF,Qiu RL,Jiang L,Xiao S
Tue Nov 29 00:00:00 EST 2022
14-3-3 proteins contribute to autophagy by modulating SINAT-mediated degradation of ATG13.
The Plant cell
Qi H,Lei X,Wang Y,Yu S,Liu T,Zhou SK,Chen JY,Chen QF,Qiu RL,Jiang L,Xiao S
Tue Nov 29 00:00:00 EST 2022
The role of NOTCH2NLC in Parkinson's disease: A clinical, neuroimaging, and pathological study.
European journal of neurology
Liu P,Yang D,Zhang F,Chen S,Xie F,Luo Y,Wang H,Chen Y,Lin Z,Wang L,Chen X,Wang B,Wu S,Ouyang Z,Cen Z,Luo W
Wed Jun 01 00:00:00 EDT 2022
Dual Effects: Intrastriatal Injection of α-syn N103/tau N368 Preformed Fibrils Promotes Endogenous α-synuclein Aggregates in the Proximal Colon.
Journal of Parkinson's disease
Wang J,Yang X,Zeng W,Zhang X,Yang X,Xu Y,Liu K,Zhang Z,Xu Y,Cao X
Tue Oct 18 00:00:00 EDT 2022
A novel circular RNA confers trastuzumab resistance in human epidermal growth factor receptor 2-positive breast cancer through regulating ferroptosis.
Environmental toxicology
Wang S,Wang Y,Li Q,Li X,Feng X
Fri Jul 01 00:00:00 EDT 2022
Nedd4-2 Haploinsufficiency in Mice Impairs the Ubiquitination of Rer1 and Increases the Susceptibility to Endoplasmic Reticulum Stress and Seizures.
Frontiers in molecular neuroscience
Liu X,Zhang L,Zhang H,Liang X,Zhang B,Tu J,Zhao Y
Sat Jul 16 00:00:00 EDT 2022
HDAC7 promotes NSCLC proliferation and metastasis via stabilization by deubiquitinase USP10 and activation of β-catenin-FGF18 pathway.
Journal of experimental & clinical cancer research : CR
Guo K,Ma Z,Zhang Y,Han L,Shao C,Feng Y,Gao F,Di S,Zhang Z,Zhang J,Tabbò F,Ekman S,Suda K,Cappuzzo F,Han J,Li X,Yan X
Fri Mar 11 00:00:00 EST 2022
Inhibition of nuclear deacetylase Sirtuin-1 induces mitochondrial acetylation and calcium overload leading to cell death.
Redox biology
Sun Y,Yang YM,Hu YY,Ouyang L,Sun ZH,Yin XF,Li N,He QY,Wang Y
Fri Jul 01 00:00:00 EDT 2022
Stress-induced epinephrine promotes epithelial-to-mesenchymal transition and stemness of CRC through the CEBPB/TRIM2/P53 axis.
Journal of translational medicine
Zhou Z,Shu Y,Bao H,Han S,Liu Z,Zhao N,Yuan W,Jian C,Shu X
Tue Jun 07 00:00:00 EDT 2022
Hsa_circ_0072309 enhances autophagy and TMZ sensitivity in glioblastoma.
CNS neuroscience & therapeutics
Yuan F,Zhang S,Sun Q,Ye L,Xu Y,Xu Z,Deng G,Zhang S,Liu B,Chen Q
Wed Jun 01 00:00:00 EDT 2022
The lncRNA BDNF-AS/WDR5/FBXW7 axis mediates ferroptosis in gastric cancer peritoneal metastasis by regulating VDAC3 ubiquitination.
International journal of biological sciences
Huang G,Xiang Z,Wu H,He Q,Dou R,Lin Z,Yang C,Huang S,Song J,Di Z,Wang S,Xiong B
Fri Apr 15 00:00:00 EDT 2022
Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy.
Acta pharmaceutica Sinica. B
Sun X,Shu Y,Ye G,Wu C,Xu M,Gao R,Huang D,Zhang J
Tue Feb 01 00:00:00 EST 2022
Pharmacological induction of AMFR increases functional EAAT2 oligomer levels and reduces epileptic seizures in mice.
JCI insight
Sha L,Li G,Zhang X,Lin Y,Qiu Y,Deng Y,Zhu W,Xu Q
Mon Aug 08 00:00:00 EDT 2022
UBE2L3 promotes squamous cell carcinoma progression in the oral cavity and hypopharynx via activating the NF-κB signaling by increasing IκBα degradation.
Cell biology international
Cui Z,Sun S,Li J,Li J,Sha T,He J,Zuo L
Sun May 01 00:00:00 EDT 2022
UBE2L3 promotes squamous cell carcinoma progression in the oral cavity and hypopharynx via activating the NF-κB signaling by increasing IκBα degradation.
Cell biology international
Cui Z,Sun S,Li J,Li J,Sha T,He J,Zuo L
Sun May 01 00:00:00 EDT 2022
Suppression of toxicity of the mutant huntingtin protein by its interacting compound, desonide.
Proceedings of the National Academy of Sciences of the United States of America
Song H,Wang C,Zhu C,Wang Z,Yang H,Wu P,Cui X,Botas J,Dang Y,Ding Y,Fei Y,Lu B
Tue Mar 08 00:00:00 EST 2022
Tubuloside B, isolated from Cistanche tubulosa, a promising agent against M1 macrophage activation via synergistically targeting Mob1 and ERK1/2.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Xiao L,Yao J,Miao Y,Ou B,Wang J,Huang Y,Zhou B,Ge L,Tian J,Zeng X
Thu Sep 01 00:00:00 EDT 2022
Ring finger protein 128 promotes, rather than inhibits, colorectal cancer progression by regulating the Hippo signaling pathway.
Frontiers in oncology
Ning S,Chen Y,Wang G,Liu Y,Yang Y,Zhang Z
Tue May 02 00:00:00 EDT 2023
The HN1/HMGB1 axis promotes the proliferation and metastasis of hepatocellular carcinoma and attenuates the chemosensitivity to oxaliplatin.
The FEBS journal
Wang R,Fu Y,Yao M,Cui X,Zhao Y,Lu X,Li Y,Lin Y,He S
Sat Oct 01 00:00:00 EDT 2022
RNF6 promotes the migration and invasion of breast cancer by promoting the ubiquitination and degradation of MST1.
Experimental and therapeutic medicine
Huang Y,Zou Y,Jie Z
Tue Feb 01 00:00:00 EST 2022
Glutathione-responsive copper-disulfiram nanoparticles for enhanced tumor chemotherapy.
Journal of controlled release : official journal of the Controlled Release Society
Chen M,Huang Z,Xia M,Ding Y,Shan T,Guan Z,Dai X,Xu X,Huang Y,Huang M,Zhao C
Sat Jan 01 00:00:00 EST 2022
UBE4B promotes the development of lung adenocarcinoma by enhancing proliferation, migration and glycolysis via PP2A/AKT signaling.
Pathology, research and practice
Wu S,Xie L,Cheng S,Fan Z,Sang H,Li Q
Fri Apr 01 00:00:00 EDT 2022
UBE4B promotes the development of lung adenocarcinoma by enhancing proliferation, migration and glycolysis via PP2A/AKT signaling.
Pathology, research and practice
Wu S,Xie L,Cheng S,Fan Z,Sang H,Li Q
Fri Apr 01 00:00:00 EDT 2022
CHIP Decline Is Associated With Isoflurane-Induced Neurodegeneration in Aged Mice.
Frontiers in neuroscience
Xu Q,Xiong J,Xu L,Wu Y,Li M,Li Q,Jiang T,Luo A,Zhang Y
Tue Apr 05 00:00:00 EDT 2022
Growth differentiation factor 11 induces skeletal muscle atrophy via a STAT3-dependent mechanism in pulmonary arterial hypertension.
Skeletal muscle
Xiang G,Ying K,Jiang P,Jia M,Sun Y,Li S,Wu X,Hao S
Fri May 06 00:00:00 EDT 2022
Identification of circular RNA BTBD7_hsa_circ_0000563 as a novel biomarker for coronary artery disease and the functional discovery of BTBD7_hsa_circ_0000563 based on peripheral blood mononuclear cells: a case control study.
Clinical proteomics
Zhou H,Gan X,He S,Wang Y,Zhang S,Chen J,Zhou Y,Hou C,Hua L,Zhang Q,Jia E
Thu Nov 03 00:00:00 EDT 2022
GNIP1 functions both as a scaffold protein and an E3 ubiquitin ligase to regulate autophagy in lung cancer.
Cell communication and signaling : CCS
Zhou F,Liu Y,Ai W,Wang Y,Gan M,Jiang Q,Han T,Wang JB
Tue Aug 30 00:00:00 EDT 2022
RNF2 promotes the progression of colon cancer by regulating ubiquitination and degradation of IRF4.
Biochimica et biophysica acta. Molecular cell research
Wang J,Ouyang X,Zhou Z,Mao S,Niu X,Li H,Xu W,Song Y,Cao J,Lai B
Sat Jan 01 00:00:00 EST 2022
SNHG25 facilitates SNORA50C accumulation to stabilize HDAC1 in neuroblastoma cells.
Cell death & disease
Zeng H,Pan J,Hu C,Yang J,Li J,Tan T,Zheng M,Shen Y,Yang T,Deng Y,Zou Y
Mon Jul 11 00:00:00 EDT 2022
Splicing factor arginine/serine-rich 8 promotes multiple myeloma malignancy and bone lesion through alternative splicing of CACYBP and exosome-based cellular communication.
Clinical and translational medicine
Zhang Y,Yu X,Sun R,Min J,Tang X,Lin Z,Xie S,Li X,Lu S,Tian Z,Gu C,Teng L,Yang Y
Tue Feb 01 00:00:00 EST 2022
Circular RNA MTCL1 promotes advanced laryngeal squamous cell carcinoma progression by inhibiting C1QBP ubiquitin degradation and mediating beta-catenin activation.
Molecular cancer
Wang Z,Sun A,Yan A,Yao J,Huang H,Gao Z,Han T,Gu J,Li N,Wu H,Li K
Sat Apr 02 00:00:00 EDT 2022
ARHGEF3 regulates the stability of ACLY to promote the proliferation of lung cancer.
Cell death & disease
Zhou F,Ai W,Zhang Y,Hu Q,Gan M,Wang JB,Han T
Fri Oct 14 00:00:00 EDT 2022
Paeoniflorin directly binds to TNFR1 to regulate podocyte necroptosis in diabetic kidney disease.
Frontiers in pharmacology
Wang X,Liu XQ,Jiang L,Huang YB,Zeng HX,Zhu QJ,Qi XM,Wu YG
Sat Sep 24 00:00:00 EDT 2022
The daily caloric restriction and alternate-day fasting ameliorated lipid dysregulation in type 2 diabetic mice by downregulating hepatic pescadillo 1.
European journal of nutrition
Zhou J,Jiang Z,Lin Y,Li C,Liu J,Tian M,Liu Y,Chen K
Mon Aug 01 00:00:00 EDT 2022
Capsaicin suppresses hepatocarcinogenesis by inhibiting the stemness of hepatic progenitor cells via SIRT1/SOX2 signaling pathway.
Cancer medicine
Xie ZQ,Li HX,Hou XJ,Huang MY,Zhu ZM,Wei LX,Tang CX
Tue Nov 01 00:00:00 EDT 2022
Ovarian tumorB1-mediated heat shock transcription factor 1 deubiquitination is critical for glycolysis and development of endometriosis.
iScience
Ling X,Lu J,Wang X,Liu L,Liu L,Wang Y,Sun Y,Ren C,Lu C,Yu Z
Fri Nov 18 00:00:00 EST 2022
CGG repeat expansion in NOTCH2NLC causes mitochondrial dysfunction and progressive neurodegeneration in Drosophila model.
Proceedings of the National Academy of Sciences of the United States of America
Yu J,Liufu T,Zheng Y,Xu J,Meng L,Zhang W,Yuan Y,Hong D,Charlet-Berguerand N,Wang Z,Deng J
Tue Oct 11 00:00:00 EDT 2022
Melatonin inhibits angiotensin II-induced atrial fibrillation through preventing degradation of Ang II Type I Receptor-Associated Protein (ATRAP).
Biochemical pharmacology
Xie X,Shen TT,Bi HL,Su ZL,Liao ZQ,Zhang Y,Shi L,Xia YL
Mon Aug 01 00:00:00 EDT 2022
PPDPF Promotes the Progression and acts as an Antiapoptotic Protein in Non-Small Cell Lung Cancer.
International journal of biological sciences
Yun M,Yingzi L,Jie G,Guanxin L,Zimei Z,Zhen C,Zhi L,Yingjie N,Lunquan S,Tao C,Yuezhen D,Chengzhi Z
Mon Mar 28 00:00:00 EDT 2022
AAA-ATPase valosin-containing protein binds the transcription factor SREBP1 and promotes its proteolytic activation by rhomboid protease RHBDL4.
The Journal of biological chemistry
Shibuya K,Ebihara K,Ebihara C,Sawayama N,Isoda M,Yamamuro D,Takahashi M,Nagashima S,Ishibashi S
Wed Jun 01 00:00:00 EDT 2022
The deubiquitinating enzyme USP20 regulates the stability of the MCL1 protein.
Biochemical and biophysical research communications
Feng J,Liu P,Li X,Zhang D,Lin H,Hou Z,Guo C,Niu Y,Dai B,Wang O,Qi M,Wang H,Zhou H
Sat Feb 19 00:00:00 EST 2022
Mitochondrial oxidative stress mediated Fe-induced ferroptosis via the NRF2-ARE pathway.
Free radical biology & medicine
Chen GH,Song CC,Pantopoulos K,Wei XL,Zheng H,Luo Z
Sun Feb 20 00:00:00 EST 2022
The feedback loop of METTL14 and USP38 regulates cell migration, invasion and EMT as well as metastasis in bladder cancer.
PLoS genetics
Huang J,Zhou W,Hao C,He Q,Tu X
Sat Oct 01 00:00:00 EDT 2022
E3 ubiquitin ligase NEURL3 promotes innate antiviral response through catalyzing K63-linked ubiquitination of IRF7.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Qi F,Zhang X,Wang L,Ren C,Zhao X,Luo J,Lu D
Mon Aug 01 00:00:00 EDT 2022
Acetylation of Checkpoint suppressor 1 enhances its stability and promotes the progression of triple-negative breast cancer.
Cell death discovery
Xu Z,Liu S,Feng C,Xu F,Kong D,Mi J,Yang C,Zhang G,Wei P,Orgil BO,Bergquist J,Tian G
Thu Dec 01 00:00:00 EST 2022
PGE2 -EP3 axis promotes brown adipose tissue formation through stabilization of WTAP RNA methyltransferase.
The EMBO journal
Tao X,Du R,Guo S,Feng X,Yu T,OuYang Q,Chen Q,Fan X,Wang X,Guo C,Li X,Xue F,Chen S,Tong M,Lazarus M,Zuo S,Yu Y,Shen Y
Tue Aug 16 00:00:00 EDT 2022
Deletion of Smurf1 attenuates liver steatosis via stabilization of p53.
Laboratory investigation; a journal of technical methods and pathology
Lin W,Zhang X,Zhang C,Li L,Zhang J,Xie P,Zhan Y,An W
Sat Oct 01 00:00:00 EDT 2022
GSK-3β inhibition elicits a neuroprotection by restoring lysosomal dysfunction in neurons via facilitation of TFEB nuclear translocation after ischemic stroke.
Brain research
Zhang Y,Wu Z,Huang Z,Liu Y,Chen X,Zhao X,He H,Deng Y
Tue Mar 01 00:00:00 EST 2022
The SPATA2/CYLD pathway contributes to doxorubicin-induced cardiomyocyte ferroptosis via enhancing ferritinophagy.
Chemico-biological interactions
Zhou YJ,Duan DQ,Lu LQ,Tang LJ,Zhang XJ,Luo XJ,Peng J
Thu Dec 01 00:00:00 EST 2022
Linear ubiquitination of PTEN impairs its function to promote prostate cancer progression.
Oncogene
Guo Y,He J,Zhang H,Chen R,Li L,Liu X,Huang C,Qiang Z,Zhou Z,Wang Y,Huang J,Zhao X,Zheng J,Chen GQ,Yu J
Sat Oct 01 00:00:00 EDT 2022
Capsaicin ameliorates diabetic retinopathy by inhibiting poldip2-induced oxidative stress.
Redox biology
Liu K,Gao X,Hu C,Gui Y,Gui S,Ni Q,Tao L,Jiang Z
Sat Oct 01 00:00:00 EDT 2022
MF-094, a potent and selective USP30 inhibitor, accelerates diabetic wound healing by inhibiting the NLRP3 inflammasome.
Experimental cell research
Li X,Wang T,Tao Y,Wang X,Li L,Liu J
Sat Jan 15 00:00:00 EST 2022
Proteasome 26S subunit, non-ATPase 1 (PSMD1) facilitated the progression of lung adenocarcinoma by the de-ubiquitination and stability of PTEN-induced kinase 1 (PINK1).
Experimental cell research
Liu L,Liu A,Dong J,Zuo Z,Liu X
Fri Apr 15 00:00:00 EDT 2022
Hemin enhances radiosensitivity of lung cancer cells through ferroptosis.
Experimental cell research
Almahi WA,Yu KN,Mohammed F,Kong P,Han W
Sat Jan 01 00:00:00 EST 2022
Hydrogen Sulfide Regulates SERCA2a Ubiquitylation via Muscle RING Finger-1 S-Sulfhydration to Affect Cardiac Contractility in db/db Mice.
Cells
Peng S,Zhao D,Li Q,Wang M,Zhang S,Pang K,Huang J,Lu F,Chen H,Zhang W
Wed Nov 02 00:00:00 EDT 2022
The MBNL1/circNTRK2/PAX5 pathway regulates aerobic glycolysis in glioblastoma cells by encoding a novel protein NTRK2-243aa.
Cell death & disease
Zhao Y,Song J,Dong W,Liu X,Yang C,Wang D,Xue Y,Ruan X,Liu L,Wang P,Zhang M,Liu Y
Mon Sep 05 00:00:00 EDT 2022
UBC Mediated by SEPT6 Inhibited the Progression of Prostate Cancer.
Mediators of inflammation
Zhang R,Yang Y,Huang H,Li T,Ye L,Lin L,Wei Y
Thu Mar 31 00:00:00 EDT 2022
PRDX2 promotes the proliferation of colorectal cancer cells by increasing the ubiquitinated degradation of p53.
Cell death & disease
Wang W,Wei J,Zhang H,Zheng X,Zhou H,Luo Y,Yang J,Deng Q,Huang S,Fu Z
Fri Jun 11 00:00:00 EDT 2021
Gankyrin activates the hedgehog signalling to drive metastasis in osteosarcoma.
Journal of cellular and molecular medicine
Wang C,Jing J,Hu X,Yu S,Yao F,Li Z,Cheng L
Sat Jun 05 00:00:00 EDT 2021
TRIM50 Suppresses Pancreatic Cancer Progression and Reverses the Epithelial-Mesenchymal Transition via Facilitating the Ubiquitous Degradation of Snail1.
Frontiers in oncology
Li R,Zhu L,Peng Y,Zhang X,Dai C,Liu D
Wed Sep 29 00:00:00 EDT 2021
USP3 promotes gastric cancer progression and metastasis by deubiquitination-dependent COL9A3/COL6A5 stabilisation.
Cell death & disease
Wu X,Wang H,Zhu D,Chai Y,Wang J,Dai W,Xiao Y,Tang W,Li J,Hong L,Pei M,Zhang J,Lin Z,Wang J,Li A,Liu S
Mon Dec 20 00:00:00 EST 2021
Aagab acts as a novel regulator of NEDD4-1-mediated Pten nuclear translocation to promote neurological recovery following hypoxic-ischemic brain damage.
Cell death and differentiation
Dai C,Wu B,Chen Y,Li X,Bai Y,Du Y,Pang Y,Wang YT,Dong Z
Sun Aug 01 00:00:00 EDT 2021
Ubiquitin-specific protease 7 promotes ferroptosis via activation of the p53/TfR1 pathway in the rat hearts after ischemia/reperfusion.
Free radical biology & medicine
Tang LJ,Zhou YJ,Xiong XM,Li NS,Zhang JJ,Luo XJ,Peng J
Fri Jan 01 00:00:00 EST 2021
Gossypol, a novel modulator of VCP, induces autophagic degradation of mutant huntingtin by promoting the formation of VCP/p97-LC3-mHTT complex.
Acta pharmacologica Sinica
Li XJ,Zhang YY,Fu YH,Zhang H,Li HX,Li QF,Li HL,Tan RK,Jiang CX,Jiang W,Li ZX,Luo C,Lu BX,Dang YJ
Fri Oct 01 00:00:00 EDT 2021
Polyglucosan body myopathy 1 may cause cognitive impairment: a case report from China.
BMC musculoskeletal disorders
Chen L,Wang N,Hu W,Yu X,Yang R,Han Y,Yan Y,Nian N,Sha C
Thu Jan 07 00:00:00 EST 2021
Autophagic Inhibition of Caveolin-1 by Compound Phyllanthus urinaria L. Activates Ubiquitination and Proteasome Degradation of β-catenin to Suppress Metastasis of Hepatitis B-Associated Hepatocellular Carcinoma.
Frontiers in pharmacology
Huang D,Yang B,Yao Y,Liao M,Zhang Y,Zeng Y,Zhang F,Wang N,Tong G
Sat Jun 26 00:00:00 EDT 2021
Osteocrin, a novel myokine, prevents diabetic cardiomyopathy via restoring proteasomal activity.
Cell death & disease
Zhang X,Hu C,Yuan XP,Yuan YP,Song P,Kong CY,Teng T,Hu M,Xu SC,Ma ZG,Tang QZ
Wed Jun 16 00:00:00 EDT 2021
The novel ZEB1-upregulated protein PRTG induced by Helicobacter pylori infection promotes gastric carcinogenesis through the cGMP/PKG signaling pathway.
Cell death & disease
Xiang T,Yuan C,Guo X,Wang H,Cai Q,Xiang Y,Luo W,Liu G
Thu Feb 04 00:00:00 EST 2021
Proteasome inhibition by bortezomib parallels a reduction in head and neck cancer cells growth, and an increase in tumor-infiltrating immune cells.
Scientific reports
Benvenuto M,Ciuffa S,Focaccetti C,Sbardella D,Fazi S,Scimeca M,Tundo GR,Barillari G,Segni M,Bonanno E,Manzari V,Modesti A,Masuelli L,Coletta M,Bei R
Fri Sep 24 00:00:00 EDT 2021
Genomic gain of RRS1 promotes hepatocellular carcinoma through reducing the RPL11-MDM2-p53 signaling.
Science advances
Cao P,Yang A,Li P,Xia X,Han Y,Zhou G,Wang R,Yang F,Li Y,Zhang Y,Cui Y,Ji H,Lu L,He F,Zhou G
Sun Aug 01 00:00:00 EDT 2021
Nuclear Receptor Interacting Protein-2 Mediates the Stabilization and Activation of β-Catenin During Podocyte Injury.
Frontiers in cell and developmental biology
Hou Q,Le W,Kan S,Shi J,Lang Y,Liu Z,Chen Z
Tue Jan 11 00:00:00 EST 2022
USP19 promotes hypoxia-induced mitochondrial division via FUNDC1 at ER-mitochondria contact sites.
The Journal of cell biology
Chai P,Cheng Y,Hou C,Yin L,Zhang D,Hu Y,Chen Q,Zheng P,Teng J,Chen J
Mon Jul 05 00:00:00 EDT 2021
USP19 promotes hypoxia-induced mitochondrial division via FUNDC1 at ER-mitochondria contact sites.
The Journal of cell biology
Chai P,Cheng Y,Hou C,Yin L,Zhang D,Hu Y,Chen Q,Zheng P,Teng J,Chen J
Mon Jul 05 00:00:00 EDT 2021
Hsa_circ_0024093 accelerates VSMC proliferation via miR-4677-3p/miR-889-3p/USP9X/YAP1 axis in in vitro model of lower extremity ASO.
Molecular therapy. Nucleic acids
Zhang X,Wang P,Yuan K,Li M,Shen Y,Que H,Wang Y,Liang W
Fri Dec 03 00:00:00 EST 2021
YY1-mediated reticulocalbin-2 upregulation promotes the hepatocellular carcinoma progression via activating MYC signaling.
American journal of cancer research
Mei C,Jiang X,Gu Y,Wu X,Ma W,Chen X,Wang G,Yao Y,Liu Y,Zhang Z,Yuan Y
Tue Jun 08 00:00:00 EDT 2021
Dysregulation of USP18/FTO/PYCR1 signaling network promotes bladder cancer development and progression.
Aging
Song W,Yang K,Luo J,Gao Z,Gao Y
Sun Jan 10 00:00:00 EST 2021
Nogo-B receptor is required for stabilizing TGF-β type I receptor and promotes the TGF-β1-induced epithelial-to-mesenchymal transition of non-small cell lung cancer.
Journal of Cancer
Wu D,Zhao B,Song Y,Chi X,Fu H,Guan T,Zhang L,Yang X,Hu K,Huang R,Jin X,Miao QR,Shao S
Mon Jan 11 00:00:00 EST 2021
Anaplasma phagocytophilum AptA enhances the UPS, autophagy, and anti-apoptosis of host cells by PSMG3.
International journal of biological macromolecules
Ma Z,Li R,Hu R,Zheng W,Yu S,Cheng K,Zhang H,Xiao Y,Yi J,Wang Z,Wang Y,Chen C
Sun Aug 01 00:00:00 EDT 2021
Hydrogen sulphide reduced the accumulation of lipid droplets in cardiac tissues of db/db mice via Hrd1 S-sulfhydration.
Journal of cellular and molecular medicine
Sun Y,Zhang L,Lu B,Wen J,Wang M,Zhang S,Li Q,Shu F,Lu F,Liu N,Peng S,Zhao Y,Dong S,Lu F,Zhang W,Wang Y
Fri Oct 01 00:00:00 EDT 2021
Efficacy and long-term safety of CRISPR/Cas9 genome editing in the SOD1-linked mouse models of ALS.
Communications biology
Deng HX,Zhai H,Shi Y,Liu G,Lowry J,Liu B,Ryan ÉB,Yan J,Yang Y,Zhang N,Yang Z,Liu E,Ma YC,Siddique T
Thu Mar 25 00:00:00 EDT 2021
Pentamidine Inhibits Ovarian Cancer Cell Proliferation and Migration by Maintaining Stability of PTEN in vitro.
Drug design, development and therapy
Wu Y,Zhang Z,Kou Z
Wed Dec 08 00:00:00 EST 2021
Spreading of TDP-43 pathology via pyramidal tract induces ALS-like phenotypes in TDP-43 transgenic mice.
Acta neuropathologica communications
Ding X,Xiang Z,Qin C,Chen Y,Tian H,Meng L,Xia D,Liu H,Song J,Fu J,Ma M,Wang X
Mon Jan 18 00:00:00 EST 2021
Nedd4-2 haploinsufficiency in mice causes increased seizure susceptibility and impaired Kir4.1 ubiquitination.
Biochimica et biophysica acta. Molecular basis of disease
Liu X,Zhang H,Zhang B,Tu J,Li X,Zhao Y
Tue Jun 01 00:00:00 EDT 2021
DUOX2 promotes the progression of colorectal cancer cells by regulating the AKT pathway and interacting with RPL3.
Carcinogenesis
Zhang X,Han J,Feng L,Zhi L,Jiang D,Yu B,Zhang Z,Gao B,Zhang C,Li M,Zhao L,Wang G
Thu Feb 11 00:00:00 EST 2021
MAD2B-mediated cell cycle reentry of podocytes is involved in the pathogenesis of FSGS.
International journal of biological sciences
Bao D,Su H,Lei CT,Tang H,Ye C,Xiong W,He FF,Lin JH,Hammes HP,Zhang C
Mon Dec 20 00:00:00 EST 2021
Samotolisib Attenuates Acute Liver Injury Through Inhibiting Caspase-11-Mediated Pyroptosis Via Regulating E3 Ubiquitin Ligase Nedd4.
Frontiers in pharmacology
Zhao YY,Wu DM,He M,Zhang F,Zhang T,Liu T,Li J,Li L,Xu Y
Tue Sep 07 00:00:00 EDT 2021
Role of the E3 ubiquitin ligase HRD1 in the regulation of serotonin transporter function.
Biochemical and biophysical research communications
Taguchi K,Kaneko M,Motoike S,Harada K,Hide I,Tanaka S,Sakai N
Fri Jan 01 00:00:00 EST 2021
Ubiquitin-dependent Argonauteprotein MEL1 degradation is essential for rice sporogenesis and phasiRNA target regulation.
The Plant cell
Lian JP,Yang YW,He RR,Yang L,Zhou YF,Lei MQ,Zhang Z,Huang JH,Cheng Y,Liu YW,Zhang YC,Chen YQ
Tue Aug 31 00:00:00 EDT 2021
FAT10 promotes the progression of bladder cancer by upregulating HK2 through the EGFR/AKT pathway.
Experimental cell research
Zou Y,Du Y,Cheng C,Deng X,Shi Z,Lu X,Hu H,Qiu J,Jiang W
Fri Jan 01 00:00:00 EST 2021
SQSTM1/ p62 oligomerization contributes to Aβ-induced inhibition of Nrf2 signaling.
Neurobiology of aging
Guo C,Zhang Y,Nie Q,Cao D,Wang X,Wan X,Liu M,Cui J,Sun J,Bai Y,Li L
Mon Feb 01 00:00:00 EST 2021
NudCL2 is an autophagy receptor that mediates selective autophagic degradation of CP110 at mother centrioles to promote ciliogenesis.
Cell research
Liu M,Zhang W,Li M,Feng J,Kuang W,Chen X,Yang F,Sun Q,Xu Z,Hua J,Yang C,Liu W,Shu Q,Yang Y,Zhou T,Xie S
Mon Nov 01 00:00:00 EDT 2021
Melatonin potentiates the cytotoxic effect of Neratinib in HER2+ breast cancer through promoting endocytosis and lysosomal degradation of HER2.
Oncogene
Liu Z,Sang X,Wang M,Liu Y,Liu J,Wang X,Liu P,Cheng H
Mon Nov 01 00:00:00 EDT 2021
CCT8 recovers WTp53-suppressed cell cycle evolution and EMT to promote colorectal cancer progression.
Oncogenesis
Liao Q,Ren Y,Yang Y,Zhu X,Zhi Y,Zhang Y,Chen Y,Ding Y,Zhao L
Fri Dec 03 00:00:00 EST 2021
Deltex3 inhibits Epithelial Mesenchymal Transition in Papillary Thyroid Carcinoma via promoting ubiquitination of XRCC5 to regulate the AKT signal pathway.
Journal of Cancer
Wang L,Huang Y,Liu C,Guo M,Ma Z,He J,Wang A,Sun X,Liu Z
Mon Jan 11 00:00:00 EST 2021
Tauroursodeoxycholic acid attenuates cisplatin-induced ototoxicity by inhibiting the accumulation and aggregation of unfolded or misfolded proteins in the endoplasmic reticulum.
Toxicology
Wen Y,Zong S,Liu T,Du P,Li H,Xiao H
Thu Apr 15 00:00:00 EDT 2021
Baicalein suppresses growth of non-small cell lung carcinoma by targeting MAP4K3.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Li J,Yan L,Luo J,Tong L,Gao Y,Feng W,Wang F,Cui W,Li S,Sun Z
Fri Jan 01 00:00:00 EST 2021
Autophagy Regulates VDAC3 Ubiquitination by FBXW7 to Promote Erastin-Induced Ferroptosis in Acute Lymphoblastic Leukemia.
Frontiers in cell and developmental biology
Zhu T,Liu B,Wu D,Xu G,Fan Y
Tue Dec 07 00:00:00 EST 2021
CDC20 promotes bone formation via APC/C dependent ubiquitination and degradation of p65.
EMBO reports
Du Y,Zhang M,Liu X,Li Z,Hu M,Tian Y,Lv L,Zhang X,Liu Y,Zhang P,Zhou Y
Mon Sep 06 00:00:00 EDT 2021
Cholesterol-associated lysosomal disorder triggers cell death of hematological malignancy: Dynamic analysis on cytotoxic effects of LW-218.
Acta pharmaceutica Sinica. B
Hu P,Li H,Sun W,Wang H,Yu X,Qing Y,Wang Z,Zhu M,Xu J,Guo Q,Hui H
Fri Oct 01 00:00:00 EDT 2021
Cholesterol-associated lysosomal disorder triggers cell death of hematological malignancy: Dynamic analysis on cytotoxic effects of LW-218.
Acta pharmaceutica Sinica. B
Hu P,Li H,Sun W,Wang H,Yu X,Qing Y,Wang Z,Zhu M,Xu J,Guo Q,Hui H
Fri Oct 01 00:00:00 EDT 2021
FBXL10 promotes ERRα protein stability and proliferation of breast cancer cells by enhancing the mono-ubiquitylation of ERRα.
Cancer letters
Yang Y,Li S,Li B,Li Y,Xia K,Aman S,Yang Y,Ahmad B,Zhao B,Wu H
Thu Apr 01 00:00:00 EDT 2021
Upstream open reading frame with NOTCH2NLC GGC expansion generates polyglycine aggregates and disrupts nucleocytoplasmic transport: implications for polyglycine diseases.
Acta neuropathologica
Zhong S,Lian Y,Luo W,Luo R,Wu X,Ji J,Ji Y,Ding J,Wang X
Wed Dec 01 00:00:00 EST 2021
Upstream open reading frame with NOTCH2NLC GGC expansion generates polyglycine aggregates and disrupts nucleocytoplasmic transport: implications for polyglycine diseases.
Acta neuropathologica
Zhong S,Lian Y,Luo W,Luo R,Wu X,Ji J,Ji Y,Ding J,Wang X
Wed Dec 01 00:00:00 EST 2021
DOC-2/DAB2 interactive protein destabilizes c-Myc to impair the growth and self-renewal of colon tumor-repopulating cells.
Cancer science
Li H,Zhou Y,Wang M,Wang H,Zhang Y,Peng R,Zhang R,Zhang M,Zhang M,Qiu P,Liu L,Zhao Q,Liu J
Mon Nov 01 00:00:00 EDT 2021
Increased AT1 receptor expression mediates vasoconstriction leading to hypertension in Snx1-/- mice.
Hypertension research : official journal of the Japanese Society of Hypertension
Liu C,Li X,Fu J,Chen K,Liao Q,Wang J,Chen C,Luo H,Jose PA,Yang Y,Yang J,Zeng C
Sun Aug 01 00:00:00 EDT 2021
Tetrandrine Modulates Rheb-mTOR Signaling-Mediated Selective Autophagy and Protects Pulmonary Fibrosis.
Frontiers in pharmacology
Liu Y,Zhong W,Zhang J,Chen W,Lu Y,Qiao Y,Zeng Z,Huang H,Cai S,Dong H
Sat Dec 11 00:00:00 EST 2021
Simultaneous silencing Aurora-A and UHRF1 inhibits colorectal cancer cell growth through regulating expression of DNMT1 and STAT1.
International journal of medical sciences
Han J,Chen X,Xu J,Chu L,Li R,Sun N,Jiang Z,Liu H,Ge X,Zheng J,Yang J,Ikezoe T
Tue Mar 15 00:00:00 EDT 2022
FV-429 induces autophagy blockage and lysosome-dependent cell death of T-cell malignancies via lysosomal dysregulation.
Cell death & disease
Hu P,Wang J,Qing Y,Li H,Sun W,Yu X,Hui H,Guo Q,Xu J
Wed Jan 13 00:00:00 EST 2021
ING2 Controls Mitochondrial Respiration via Modulating MRPL12 Ubiquitination in Renal Tubular Epithelial Cells.
Frontiers in cell and developmental biology
Yang Y,Li C,Gu X,Zhen J,Zhu S,Lv T,Wan Q,Liu Y
Fri Aug 27 00:00:00 EDT 2021
Hepatitis B Surface Antigen Suppresses the Activation of Nuclear Factor Kappa B Pathway via Interaction With the TAK1-TAB2 Complex.
Frontiers in immunology
Deng F,Xu G,Cheng Z,Huang Y,Ma C,Luo C,Yu C,Wang J,Xu X,Liu S,Zhu Y
Mon Jun 28 00:00:00 EDT 2021
Anti-tumor activity of a novel proteasome inhibitor D395 against multiple myeloma and its lower cardiotoxicity compared with carfilzomib.
Cell death & disease
Shen X,Wu C,Lei M,Yan Q,Zhang H,Zhang L,Wang X,Yang Y,Li J,Zhu Y,Chen L
Fri Apr 30 00:00:00 EDT 2021
Hsa_circ_0005915 promotes N,N-dimethylformamide-induced oxidative stress in HL-7702 cells through NRF2/ARE axis.
Toxicology
Liu Z,He Q,Liu Y,Zhang Y,Cui M,Peng H,Wang Y,Chen S,Li D,Chen L,Xiao Y,Chen W,Wang Q
Wed Jun 30 00:00:00 EDT 2021
Voltage-gated sodium channels β3 subunit promotes tumorigenesis in hepatocellular carcinoma by facilitating p53 degradation.
FEBS letters
Li S,Han J,Guo G,Sun Y,Zhang T,Zhao M,Xu Y,Cui Y,Liu Y,Zhang J
Sat Feb 01 00:00:00 EST 2020
Down-Regulated CUEDC2 Increases GDNF Expression by Stabilizing CREB Through Reducing Its Ubiquitination in Glioma.
Neurochemical research
Liu XF,Tang CX,Zhang L,Tong SY,Wang Y,Abdulrahman AA,Ji GQ,Gao Y,Gao DS,Zhang BL
Tue Dec 01 00:00:00 EST 2020
HDAC6, A Novel Cargo for Autophagic Clearance of Stress Granules, Mediates the Repression of the Type I Interferon Response During Coxsackievirus A16 Infection.
Frontiers in microbiology
Zheng Y,Zhu G,Tang Y,Yan J,Han S,Yin J,Peng B,He X,Liu W
Mon Sep 28 00:00:00 EDT 2020
Ubiquitin E3 Ligase c-Cbl Is a Host Negative Regulator of Nef Protein of HIV-1.
Frontiers in microbiology
Zhang HG,Guo J,Yuan Y,Zuo Y,Liu J,Zhu L,Miao Y,Chen X,Jin L,Huang F,Ren T,He J,Shi W,Wen Z,Zhu C,Zheng H,Dong C,Qian F
Fri Dec 18 00:00:00 EST 2020
Exogenous H2S Promoted USP8 Sulfhydration to Regulate Mitophagy in the Hearts of db/db Mice.
Aging and disease
Sun Y,Lu F,Yu X,Wang B,Chen J,Lu F,Peng S,Sun X,Yu M,Chen H,Wang Y,Zhang L,Liu N,Du H,Zhao D,Zhang W
Wed Apr 01 00:00:00 EDT 2020
Cancer Cell enters reversible quiescence through Intracellular Acidification to resist Paclitaxel Cytotoxicity.
International journal of medical sciences
Jia M,Zheng D,Wang X,Zhang Y,Chen S,Cai X,Mo L,Hu Z,Li H,Zhou Z,Li J
Mon Mar 08 00:00:00 EST 2021
Arabidopsis SINAT Proteins Control Autophagy by Mediating Ubiquitylation and Degradation of ATG13.
The Plant cell
Qi H,Li J,Xia FN,Chen JY,Lei X,Han MQ,Xie LJ,Zhou QM,Xiao S
Wed Jan 01 00:00:00 EST 2020
Hydrogen sulphide ameliorating skeletal muscle atrophy in db/db mice via Muscle RING finger 1 S-sulfhydration.
Journal of cellular and molecular medicine
Lu F,Lu B,Zhang L,Wen J,Wang M,Zhang S,Li Q,Shu F,Sun Y,Liu N,Peng S,Zhao Y,Dong S,Zhao D,Lu F,Zhang W
Sat Aug 01 00:00:00 EDT 2020
Hydrogen sulfide regulates muscle RING finger-1 protein S-sulfhydration at Cys44 to prevent cardiac structural damage in diabetic cardiomyopathy.
British journal of pharmacology
Sun X,Zhao D,Lu F,Peng S,Yu M,Liu N,Sun Y,Du H,Wang B,Chen J,Dong S,Lu F,Zhang W
Sat Feb 01 00:00:00 EST 2020
MAFG-AS1 promotes tumor progression via regulation of the HuR/PTBP1 axis in bladder urothelial carcinoma.
Clinical and translational medicine
Xiao M,Liu J,Xiang L,Zhao K,He D,Zeng Q,Zhang Q,Xie D,Deng M,Zhu Y,Zhang Y,Liu Y,Bo H,Liu X,Chen X,Gong L,Bao Y,Hu Y,Cheng Y,Deng L,Zhu R,Xing X,Zhou M,Xiong W,Zhou Y,Zhou J,Li X,Cao K
Tue Dec 01 00:00:00 EST 2020
PHLDA1 promotes microglia-mediated neuroinflammation via regulating K63-linked ubiquitination of TRAF6.
Brain, behavior, and immunity
Han C,Yan P,He T,Cheng J,Zheng W,Zheng LT,Zhen X
Sat Aug 01 00:00:00 EDT 2020
The effect and mechanism of 19S proteasome PSMD11/Rpn6 subunit in D-Galactose induced mimetic aging models.
Experimental cell research
Wu H,Sun H,He Z,Chen X,Li Y,Zhao X,Kong W,Kong W
Tue Sep 01 00:00:00 EDT 2020
Myc-mediated SDHA acetylation triggers epigenetic regulation of gene expression and tumorigenesis.
Nature metabolism
Li ST,Huang D,Shen S,Cai Y,Xing S,Wu G,Jiang Z,Hao Y,Yuan M,Wang N,Zhu L,Yan R,Yang D,Wang L,Liu Z,Hu X,Zhou R,Qu K,Li A,Duan X,Zhang H,Gao P
Sun Mar 01 00:00:00 EST 2020
α-synuclein strains that cause distinct pathologies differentially inhibit proteasome.
eLife
Suzuki G,Imura S,Hosokawa M,Katsumata R,Nonaka T,Hisanaga SI,Saeki Y,Hasegawa M
Wed Jul 22 00:00:00 EDT 2020
Crosstalk between cardiomyocytes and noncardiomyocytes is essential to prevent cardiomyocyte apoptosis induced by proteasome inhibition.
Cell death & disease
Guo F,Zhang CC,Yin XH,Li T,Fang CH,He XB
Sat Sep 19 00:00:00 EDT 2020
Lanosterol modulates proteostasis via dissolving cytosolic sequestosomes/aggresome-like induced structures.
Biochimica et biophysica acta. Molecular cell research
Hu LD,Wang J,Chen XJ,Yan YB
Sat Feb 01 00:00:00 EST 2020
Tobramycin suppresses HUWE1 degradation to control MCL-1 stability during tumour development.
Clinical and experimental pharmacology & physiology
He J,Wu S,Li X,Tang L,Chen H,Qin L,Xie J,Lu T,Xu W
Tue Sep 01 00:00:00 EDT 2020
LINC00452 promotes ovarian carcinogenesis through increasing ROCK1 by sponging miR-501-3p and suppressing ubiquitin-mediated degradation.
Aging
Yang J,Wang WG,Zhang KQ
Mon Nov 09 00:00:00 EST 2020
WDHD1 Leads to Cisplatin Resistance by Promoting MAPRE2 Ubiquitination in Lung Adenocarcinoma.
Frontiers in oncology
Gong L,Xiao M,He D,Hu Y,Zhu Y,Xiang L,Bao Y,Liu X,Zeng Q,Liu J,Zhou M,Zhou Y,Cheng Y,Zhang Y,Deng L,Zhu R,Lan H,Cao K
Mon Sep 28 00:00:00 EDT 2020
Long non-coding RNA LOC100133669 promotes cell proliferation in oesophageal squamous cell carcinoma.
Cell proliferation
Guan Z,Wang Y,Wang Y,Liu X,Wang Y,Zhang W,Chi X,Dong Y,Liu X,Shao S,Zhan Q
Wed Apr 01 00:00:00 EDT 2020
A robust TDP-43 knock-in mouse model of ALS.
Acta neuropathologica communications
Huang SL,Wu LS,Lee M,Chang CW,Cheng WC,Fang YS,Chen YR,Cheng PL,Shen CJ
Tue Jan 21 00:00:00 EST 2020
SPOP attenuates migration and invasion of choriocarcinoma cells by promoting DHX9 degradation.
American journal of cancer research
Yuan D,Chen Y,Yang Z,Li G,Wu M,Jiang J,Li D,Yu Q
Mon Sep 28 00:00:00 EDT 2020
SUMOylation Protects FASN Against Proteasomal Degradation in Breast Cancer Cells Treated with Grape Leaf Extract.
Biomolecules
Floris A,Mazarei M,Yang X,Robinson AE,Zhou J,Barberis A,D'hallewin G,Azara E,Spissu Y,Iglesias-Ara A,Orrù S,Tomasi ML
Tue Mar 31 00:00:00 EDT 2020
p53 Affects PGC1α Stability Through AKT/GSK-3β to Enhance Cisplatin Sensitivity in Non-Small Cell Lung Cancer.
Frontiers in oncology
Deng X,Li Y,Gu S,Chen Y,Yu B,Su J,Sun L,Liu Y
Mon Sep 28 00:00:00 EDT 2020
Trehalose Alleviates Crystalline Silica-Induced Pulmonary Fibrosis via Activation of the TFEB-Mediated Autophagy-Lysosomal System in Alveolar Macrophages.
Cells
He X,Chen S,Li C,Ban J,Wei Y,He Y,Liu F,Chen Y,Chen J
Sat Jan 04 00:00:00 EST 2020
Parkin interacts with Mitofilin to increase dopaminergic neuron death in response to Parkinson's disease-related stressors.
American journal of translational research
Imam Aliagan AD,Ahwazi MD,Tombo N,Feng Y,Bopassa JC
Fri Nov 10 00:00:00 EST 2023
Parkin interacts with Mitofilin to increase dopaminergic neuron death in response to Parkinson's disease-related stressors.
American journal of translational research
Imam Aliagan AD,Ahwazi MD,Tombo N,Feng Y,Bopassa JC
Fri Nov 10 00:00:00 EST 2023
Involvement of p53 Acetylation in Growth Suppression of Cutaneous T-Cell Lymphomas Induced by HDAC Inhibition.
The Journal of investigative dermatology
Yu X,Li H,Zhu M,Hu P,Liu X,Qing Y,Wang X,Wang H,Wang Z,Xu J,Tan R,Guo Q,Hui H
Thu Oct 01 00:00:00 EDT 2020
Hsp90ab1 stabilizes LRP5 to promote epithelial-mesenchymal transition via activating of AKT and Wnt/β-catenin signaling pathways in gastric cancer progression.
Oncogene
Wang H,Deng G,Ai M,Xu Z,Mou T,Yu J,Liu H,Wang S,Li G
Fri Feb 01 00:00:00 EST 2019
Hsp90ab1 stabilizes LRP5 to promote epithelial-mesenchymal transition via activating of AKT and Wnt/β-catenin signaling pathways in gastric cancer progression.
Oncogene
Wang H,Deng G,Ai M,Xu Z,Mou T,Yu J,Liu H,Wang S,Li G
Fri Feb 01 00:00:00 EST 2019
THZ1 suppresses human non-small-cell lung cancer cells in vitro through interference with cancer metabolism.
Acta pharmacologica Sinica
Cheng ZJ,Miao DL,Su QY,Tang XL,Wang XL,Deng LB,Shi HD,Xin HB
Sat Jun 01 00:00:00 EDT 2019
THZ1 suppresses human non-small-cell lung cancer cells in vitro through interference with cancer metabolism.
Acta pharmacologica Sinica
Cheng ZJ,Miao DL,Su QY,Tang XL,Wang XL,Deng LB,Shi HD,Xin HB
Sat Jun 01 00:00:00 EDT 2019
YY1-regulated LINC00152 promotes triple negative breast cancer progression by affecting on stability of PTEN protein.
Biochemical and biophysical research communications
Shen X,Zhong J,Yu P,Zhao Q,Huang T
Tue Feb 05 00:00:00 EST 2019
YY1-regulated LINC00152 promotes triple negative breast cancer progression by affecting on stability of PTEN protein.
Biochemical and biophysical research communications
Shen X,Zhong J,Yu P,Zhao Q,Huang T
Tue Feb 05 00:00:00 EST 2019
Cinobufotalin powerfully reversed EBV-miR-BART22-induced cisplatin resistance via stimulating MAP2K4 to antagonize non-muscle myosin heavy chain IIA/glycogen synthase 3β/β-catenin signaling pathway.
EBioMedicine
Liu Y,Jiang Q,Liu X,Lin X,Tang Z,Liu C,Zhou J,Zhao M,Li X,Cheng Z,Li L,Xie Y,Liu Z,Fang W
Tue Oct 01 00:00:00 EDT 2019
Deletion of Tbk1 disrupts autophagy and reproduces behavioral and locomotor symptoms of FTD-ALS in mice.
Aging
Duan W,Guo M,Yi L,Zhang J,Bi Y,Liu Y,Li Y,Li Z,Ma Y,Zhang G,Liu Y,Song X,Li C
Tue Apr 30 00:00:00 EDT 2019
Deletion of Tbk1 disrupts autophagy and reproduces behavioral and locomotor symptoms of FTD-ALS in mice.
Aging
Duan W,Guo M,Yi L,Zhang J,Bi Y,Liu Y,Li Y,Li Z,Ma Y,Zhang G,Liu Y,Song X,Li C
Tue Apr 30 00:00:00 EDT 2019
TRIM28 protects CARM1 from proteasome-mediated degradation to prevent colorectal cancer metastasis.
Science bulletin
Cui J,Hu J,Ye Z,Fan Y,Li Y,Wang G,Wang L,Wang Z
Tue Jul 30 00:00:00 EDT 2019
Autosomal dominant mitochondrial membrane protein-associated neurodegeneration (MPAN).
Molecular genetics & genomic medicine
Gregory A,Lotia M,Jeong SY,Fox R,Zhen D,Sanford L,Hamada J,Jahic A,Beetz C,Freed A,Kurian MA,Cullup T,van der Weijden MCM,Nguyen V,Setthavongsack N,Garcia D,Krajbich V,Pham T,Woltjer R,George BP,Minks KQ,Paciorkowski AR,Hogarth P,Jankovic J,Hayflick SJ
Mon Jul 01 00:00:00 EDT 2019
Fludarabine as an Adjuvant Improves Newcastle Disease Virus-Mediated Antitumor Immunity in Hepatocellular Carcinoma.
Molecular therapy oncolytics
Meng G,Fei Z,Fang M,Li B,Chen A,Xu C,Xia M,Yu D,Wei J
Fri Jun 28 00:00:00 EDT 2019
STAT3 Regulates the Type I IFN-Mediated Antiviral Response by Interfering with the Nuclear Entry of STAT1.
International journal of molecular sciences
Wang H,Yuan M,Wang S,Zhang L,Zhang R,Zou X,Wang X,Chen D,Wu Z
Mon Sep 30 00:00:00 EDT 2019
The immunoproteasome catalytic β5i subunit regulates cardiac hypertrophy by targeting the autophagy protein ATG5 for degradation.
Science advances
Xie X,Bi HL,Lai S,Zhang YL,Li N,Cao HJ,Han L,Wang HX,Li HH
Wed May 01 00:00:00 EDT 2019
The endogenous retrovirus-derived long noncoding RNA TROJAN promotes triple-negative breast cancer progression via ZMYND8 degradation.
Science advances
Jin X,Xu XE,Jiang YZ,Liu YR,Sun W,Guo YJ,Ren YX,Zuo WJ,Hu X,Huang SL,Shen HJ,Lan F,He YF,Hu GH,Di GH,He XH,Li DQ,Liu S,Yu KD,Shao ZM
Fri Mar 01 00:00:00 EST 2019
The deubiquitinating enzyme OTUD1 antagonizes BH3-mimetic inhibitor induced cell death through regulating the stability of the MCL1 protein.
Cancer cell international
Wu L,Lin Y,Feng J,Qi Y,Wang X,Lin Q,Shi W,Zheng E,Wang W,Hou Z,Lin H,Yu C,He Y,Xu Y,Yang H,Lin L,Li L
Sun Apr 10 00:00:00 EDT 2022
Autophagy protects HUVECs against ER stress-mediated apoptosis under simulated microgravity.
Apoptosis : an international journal on programmed cell death
Li CF,Pan YK,Gao Y,Shi F,Wang YC,Sun XQ
Tue Oct 01 00:00:00 EDT 2019
Nilotinib: A Tyrosine Kinase Inhibitor Mediates Resistance to Intracellular Mycobacterium Via Regulating Autophagy.
Cells
Hussain T,Zhao D,Shah SZA,Sabir N,Wang J,Liao Y,Song Y,Dong H,Hussain Mangi M,Ni J,Yang L,Zhou X
Sun May 26 00:00:00 EDT 2019
Nilotinib: A Tyrosine Kinase Inhibitor Mediates Resistance to Intracellular Mycobacterium Via Regulating Autophagy.
Cells
Hussain T,Zhao D,Shah SZA,Sabir N,Wang J,Liao Y,Song Y,Dong H,Hussain Mangi M,Ni J,Yang L,Zhou X
Sun May 26 00:00:00 EDT 2019
Long Noncoding RNA-DACH1 (Dachshund Homolog 1) Regulates Cardiac Function by Inhibiting SERCA2a (Sarcoplasmic Reticulum Calcium ATPase 2a).
Hypertension (Dallas, Tex. : 1979)
Cai B,Zhang Y,Zhao Y,Wang J,Li T,Zhang Y,Jiang Y,Jin X,Xue G,Li P,Sun Y,Huang Q,Zhang X,Su W,Yang Y,Sun Y,Shi L,Li X,Lu Y,Yang B,Pan Z
Tue Oct 01 00:00:00 EDT 2019
Kindlin-2 links mechano-environment to proline synthesis and tumor growth.
Nature communications
Guo L,Cui C,Zhang K,Wang J,Wang Y,Lu Y,Chen K,Yuan J,Xiao G,Tang B,Sun Y,Wu C
Tue Feb 19 00:00:00 EST 2019
Downregulation of MUTYH contributes to cisplatin‑resistance of esophageal squamous cell carcinoma cells by promoting Twist‑mediated EMT.
Oncology reports
Guo Y,Jia Y,Wang S,Liu N,Gao D,Zhang L,Lin Z,Wang S,Kong F,Peng C,Liu Y
Sun Dec 01 00:00:00 EST 2019
USP49 potently stabilizes APOBEC3G protein by removing ubiquitin and inhibits HIV-1 replication.
eLife
Pan T,Song Z,Wu L,Liu G,Ma X,Peng Z,Zhou M,Liang L,Liu B,Liu J,Zhang J,Zhang X,Huang R,Zhao J,Li Y,Ling X,Luo Y,Tang X,Cai W,Deng K,Li L,Zhang H
Fri Aug 09 00:00:00 EDT 2019
Myricetin Alleviates Pathological Cardiac Hypertrophy via TRAF6/TAK1/MAPK and Nrf2 Signaling Pathway.
Oxidative medicine and cellular longevity
Liao HH,Zhang N,Meng YY,Feng H,Yang JJ,Li WJ,Chen S,Wu HM,Deng W,Tang QZ
Thu Jun 25 00:00:00 EDT 2020
Long non-coding RNA GBCDRlnc1 induces chemoresistance of gallbladder cancer cells by activating autophagy.
Molecular cancer
Cai Q,Wang S,Jin L,Weng M,Zhou D,Wang J,Tang Z,Quan Z
Fri Apr 05 00:00:00 EDT 2019
Long non-coding RNA GBCDRlnc1 induces chemoresistance of gallbladder cancer cells by activating autophagy.
Molecular cancer
Cai Q,Wang S,Jin L,Weng M,Zhou D,Wang J,Tang Z,Quan Z
Fri Apr 05 00:00:00 EDT 2019
TRIM59 regulates autophagy through modulating both the transcription and the ubiquitination of BECN1.
Autophagy
Han T,Guo M,Gan M,Yu B,Tian X,Wang JB
Tue Oct 22 00:00:00 EDT 2019
TRIM59 regulates autophagy through modulating both the transcription and the ubiquitination of BECN1.
Autophagy
Han T,Guo M,Gan M,Yu B,Tian X,Wang JB
Tue Oct 22 00:00:00 EDT 2019
Downregulation of glycine decarboxylase enhanced cofilin-mediated migration in hepatocellular carcinoma cells.
Free radical biology & medicine
Zhuang H,Li Q,Zhang X,Ma X,Wang Z,Liu Y,Yi X,Chen R,Han F,Zhang N,Li Y
Sun May 20 00:00:00 EDT 2018
Downregulation of glycine decarboxylase enhanced cofilin-mediated migration in hepatocellular carcinoma cells.
Free radical biology & medicine
Zhuang H,Li Q,Zhang X,Ma X,Wang Z,Liu Y,Yi X,Chen R,Han F,Zhang N,Li Y
Sun May 20 00:00:00 EDT 2018
Identification of Residues Controlling Restriction versus Enhancing Activities of IFITM Proteins on Entry of Human Coronaviruses.
Journal of virology
Zhao X,Sehgal M,Hou Z,Cheng J,Shu S,Wu S,Guo F,Le Marchand SJ,Lin H,Chang J,Guo JT
Thu Mar 15 00:00:00 EDT 2018
Identification of Residues Controlling Restriction versus Enhancing Activities of IFITM Proteins on Entry of Human Coronaviruses.
Journal of virology
Zhao X,Sehgal M,Hou Z,Cheng J,Shu S,Wu S,Guo F,Le Marchand SJ,Lin H,Chang J,Guo JT
Thu Mar 15 00:00:00 EDT 2018
Hematopoietic Substrate-1-Associated Protein X-1 Regulates the Proliferation and Apoptosis of Endothelial Progenitor Cells Through Akt Pathway Modulation.
Stem cells (Dayton, Ohio)
Guo XB,Deng X,Wei Y
Thu Mar 01 00:00:00 EST 2018
Hematopoietic Substrate-1-Associated Protein X-1 Regulates the Proliferation and Apoptosis of Endothelial Progenitor Cells Through Akt Pathway Modulation.
Stem cells (Dayton, Ohio)
Guo XB,Deng X,Wei Y
Thu Mar 01 00:00:00 EST 2018
The N-terminal ubiquitin-associated domain of Cezanne is crucial for its function to suppress NF-κB pathway.
Journal of cellular biochemistry
Ji Y,Cao L,Zeng L,Zhang Z,Xiao Q,Guan P,Chen S,Chen Y,Wang M,Guo D
Thu Feb 01 00:00:00 EST 2018
The N-terminal ubiquitin-associated domain of Cezanne is crucial for its function to suppress NF-κB pathway.
Journal of cellular biochemistry
Ji Y,Cao L,Zeng L,Zhang Z,Xiao Q,Guan P,Chen S,Chen Y,Wang M,Guo D
Thu Feb 01 00:00:00 EST 2018
CRISPR/Cas9-Targeted Deletion of Polyglutamine in Spinocerebellar Ataxia Type 3-Derived Induced Pluripotent Stem Cells.
Stem cells and development
Ouyang S,Xie Y,Xiong Z,Yang Y,Xian Y,Ou Z,Song B,Chen Y,Xie Y,Li H,Sun X
Fri Jun 01 00:00:00 EDT 2018
CRISPR/Cas9-Targeted Deletion of Polyglutamine in Spinocerebellar Ataxia Type 3-Derived Induced Pluripotent Stem Cells.
Stem cells and development
Ouyang S,Xie Y,Xiong Z,Yang Y,Xian Y,Ou Z,Song B,Chen Y,Xie Y,Li H,Sun X
Fri Jun 01 00:00:00 EDT 2018
Pyk2 deficiency potentiates osteoblast differentiation and mineralizing activity in response to estrogen or raloxifene.
Molecular and cellular endocrinology
Posritong S,Hong JM,Eleniste PP,McIntyre PW,Wu JL,Himes ER,Patel V,Kacena MA,Bruzzaniti A
Mon Oct 15 00:00:00 EDT 2018
Pyk2 deficiency potentiates osteoblast differentiation and mineralizing activity in response to estrogen or raloxifene.
Molecular and cellular endocrinology
Posritong S,Hong JM,Eleniste PP,McIntyre PW,Wu JL,Himes ER,Patel V,Kacena MA,Bruzzaniti A
Mon Oct 15 00:00:00 EDT 2018
SIRT3 deacetylates and promotes degradation of P53 in PTEN-defective non-small cell lung cancer.
Journal of cancer research and clinical oncology
Xiong Y,Wang L,Wang S,Wang M,Zhao J,Zhang Z,Li X,Jia L,Han Y
Thu Feb 01 00:00:00 EST 2018
M-Phase Phosphoprotein 9 regulates ciliogenesis by modulating CP110-CEP97 complex localization at the mother centriole.
Nature communications
Huang N,Zhang D,Li F,Chai P,Wang S,Teng J,Chen J
Tue Oct 30 00:00:00 EDT 2018
Ubiquitin-Specific Protease USP6 Regulates the Stability of the c-Jun Protein.
Molecular and cellular biology
Li L,Yang H,He Y,Li T,Feng J,Chen W,Ao L,Shi X,Lin Y,Liu H,Zheng E,Lin Q,Bu J,Zeng Y,Zheng M,Xu Y,Liao Z,Lin J,Lin D
Mon Jan 15 00:00:00 EST 2018
14-3-3ζ binds to hepatitis B virus protein X and maintains its protein stability in hepatocellular carcinoma cells.
Cancer medicine
Tang Y,Zhang Y,Wang C,Sun Z,Li L,Dong J,Zhou W
Thu Nov 01 00:00:00 EDT 2018
14-3-3ζ binds to hepatitis B virus protein X and maintains its protein stability in hepatocellular carcinoma cells.
Cancer medicine
Tang Y,Zhang Y,Wang C,Sun Z,Li L,Dong J,Zhou W
Thu Nov 01 00:00:00 EDT 2018
Temozolomide-perillyl alcohol conjugate downregulates O6-methylguanin DNA methltransferase via inducing ubiquitination-dependent proteolysis in non-small cell lung cancer.
Cell death & disease
Song X,Xie L,Chang M,Geng X,Wang X,Chen TC,Song X
Fri Feb 09 00:00:00 EST 2018
Temozolomide-perillyl alcohol conjugate downregulates O6-methylguanin DNA methltransferase via inducing ubiquitination-dependent proteolysis in non-small cell lung cancer.
Cell death & disease
Song X,Xie L,Chang M,Geng X,Wang X,Chen TC,Song X
Fri Feb 09 00:00:00 EST 2018
The LINC01138 drives malignancies via activating arginine methyltransferase 5 in hepatocellular carcinoma.
Nature communications
Li Z,Zhang J,Liu X,Li S,Wang Q,Hu Z,Yu T,Ding J,Li J,Yao M,Fan J,Huang S,Gao Q,Zhao Y,He X
Fri Apr 20 00:00:00 EDT 2018
The LINC01138 drives malignancies via activating arginine methyltransferase 5 in hepatocellular carcinoma.
Nature communications
Li Z,Zhang J,Liu X,Li S,Wang Q,Hu Z,Yu T,Ding J,Li J,Yao M,Fan J,Huang S,Gao Q,Zhao Y,He X
Fri Apr 20 00:00:00 EDT 2018
Liposomal honokiol induced lysosomal degradation of Hsp90 client proteins and protective autophagy in both gefitinib-sensitive and gefitinib-resistant NSCLC cells.
Biomaterials
Yang J,Wu W,Wen J,Ye H,Luo H,Bai P,Tang M,Wang F,Zheng L,Yang S,Li W,Peng A,Yang L,Wan L,Chen L
Sun Oct 01 00:00:00 EDT 2017
Liposomal honokiol induced lysosomal degradation of Hsp90 client proteins and protective autophagy in both gefitinib-sensitive and gefitinib-resistant NSCLC cells.
Biomaterials
Yang J,Wu W,Wen J,Ye H,Luo H,Bai P,Tang M,Wang F,Zheng L,Yang S,Li W,Peng A,Yang L,Wan L,Chen L
Sun Oct 01 00:00:00 EDT 2017
TRAF Family Proteins Regulate Autophagy Dynamics by Modulating AUTOPHAGY PROTEIN6 Stability in Arabidopsis.
The Plant cell
Qi H,Xia FN,Xie LJ,Yu LJ,Chen QF,Zhuang XH,Wang Q,Li F,Jiang L,Xie Q,Xiao S
Sat Apr 01 00:00:00 EDT 2017
TRAF Family Proteins Regulate Autophagy Dynamics by Modulating AUTOPHAGY PROTEIN6 Stability in Arabidopsis.
The Plant cell
Qi H,Xia FN,Xie LJ,Yu LJ,Chen QF,Zhuang XH,Wang Q,Li F,Jiang L,Xie Q,Xiao S
Sat Apr 01 00:00:00 EDT 2017
A novel histone deacetylase inhibitor TMU-35435 enhances etoposide cytotoxicity through the proteasomal degradation of DNA-PKcs in triple-negative breast cancer.
Cancer letters
Wu YH,Hong CW,Wang YC,Huang WJ,Yeh YL,Wang BJ,Wang YJ,Chiu HW
Tue Aug 01 00:00:00 EDT 2017
A novel histone deacetylase inhibitor TMU-35435 enhances etoposide cytotoxicity through the proteasomal degradation of DNA-PKcs in triple-negative breast cancer.
Cancer letters
Wu YH,Hong CW,Wang YC,Huang WJ,Yeh YL,Wang BJ,Wang YJ,Chiu HW
Tue Aug 01 00:00:00 EDT 2017
AMPK Serves as a Therapeutic Target Against Anemia of Inflammation.
Antioxidants & redox signaling
Wang M,Xin H,Tang W,Li Y,Zhang Z,Fan L,Miao L,Tan B,Wang X,Zhu YZ
Thu Aug 10 00:00:00 EDT 2017
AMPK Serves as a Therapeutic Target Against Anemia of Inflammation.
Antioxidants & redox signaling
Wang M,Xin H,Tang W,Li Y,Zhang Z,Fan L,Miao L,Tan B,Wang X,Zhu YZ
Thu Aug 10 00:00:00 EDT 2017
Endoplasmic Reticulum Stress Is Involved in Cochlear Cell Apoptosis in a Cisplatin-Induced Ototoxicity Rat Model.
Audiology & neuro-otology
Zong S,Liu T,Wan F,Chen P,Luo P,Xiao H
Fri Jul 27 00:00:00 EDT 2018
Endoplasmic Reticulum Stress Is Involved in Cochlear Cell Apoptosis in a Cisplatin-Induced Ototoxicity Rat Model.
Audiology & neuro-otology
Zong S,Liu T,Wan F,Chen P,Luo P,Xiao H
Fri Jul 27 00:00:00 EDT 2018
Role of the Ubiquitin C-Terminal Hydrolase L1-Modulated Ubiquitin Proteasome System in Auditory Cortex Senescence.
ORL; journal for oto-rhino-laryngology and its related specialties
Zhang Y,Huang X,Zhao XY,Hu YJ,Sun HY,Kong WJ
Mon Apr 09 00:00:00 EDT 2018
Role of the Ubiquitin C-Terminal Hydrolase L1-Modulated Ubiquitin Proteasome System in Auditory Cortex Senescence.
ORL; journal for oto-rhino-laryngology and its related specialties
Zhang Y,Huang X,Zhao XY,Hu YJ,Sun HY,Kong WJ
Mon Apr 09 00:00:00 EDT 2018
MDM2 Contributes to High Glucose-Induced Glomerular Mesangial Cell Proliferation and Extracellular Matrix Accumulation via Notch1.
Scientific reports
Lei CT,Tang H,Ye C,You CQ,Zhang J,Zhang CY,Xiong W,Su H,Zhang C
Mon Sep 04 00:00:00 EDT 2017
MDM2 Contributes to High Glucose-Induced Glomerular Mesangial Cell Proliferation and Extracellular Matrix Accumulation via Notch1.
Scientific reports
Lei CT,Tang H,Ye C,You CQ,Zhang J,Zhang CY,Xiong W,Su H,Zhang C
Mon Sep 04 00:00:00 EDT 2017
A novel glutaminase inhibitor-968 inhibits the migration and proliferation of non-small cell lung cancer cells by targeting EGFR/ERK signaling pathway.
Oncotarget
Han T,Guo M,Zhang T,Gan M,Xie C,Wang JB
Tue Apr 25 00:00:00 EDT 2017
HAX-1 Protects Glioblastoma Cells from Apoptosis through the Akt1 Pathway.
Frontiers in cellular neuroscience
Deng X,Song L,Zhao W,Wei Y,Guo XB
Wed Sep 30 00:00:00 EDT 2020
HAX-1 Protects Glioblastoma Cells from Apoptosis through the Akt1 Pathway.
Frontiers in cellular neuroscience
Deng X,Song L,Zhao W,Wei Y,Guo XB
Wed Sep 30 00:00:00 EDT 2020
HAX-1 Protects Glioblastoma Cells from Apoptosis through the Akt1 Pathway.
Frontiers in cellular neuroscience
Deng X,Song L,Zhao W,Wei Y,Guo XB
Wed Sep 30 00:00:00 EDT 2020
HAX-1 Protects Glioblastoma Cells from Apoptosis through the Akt1 Pathway.
Frontiers in cellular neuroscience
Deng X,Song L,Zhao W,Wei Y,Guo XB
Wed Sep 30 00:00:00 EDT 2020
Exogenous H2S facilitating ubiquitin aggregates clearance via autophagy attenuates type 2 diabetes-induced cardiomyopathy.
Cell death & disease
Wu J,Tian Z,Sun Y,Lu C,Liu N,Gao Z,Zhang L,Dong S,Yang F,Zhong X,Xu C,Lu F,Zhang W
Thu Aug 10 00:00:00 EDT 2017
Exogenous H2S facilitating ubiquitin aggregates clearance via autophagy attenuates type 2 diabetes-induced cardiomyopathy.
Cell death & disease
Wu J,Tian Z,Sun Y,Lu C,Liu N,Gao Z,Zhang L,Dong S,Yang F,Zhong X,Xu C,Lu F,Zhang W
Thu Aug 10 00:00:00 EDT 2017
Exogenous H2S facilitating ubiquitin aggregates clearance via autophagy attenuates type 2 diabetes-induced cardiomyopathy.
Cell death & disease
Wu J,Tian Z,Sun Y,Lu C,Liu N,Gao Z,Zhang L,Dong S,Yang F,Zhong X,Xu C,Lu F,Zhang W
Thu Aug 10 00:00:00 EDT 2017
Proteasome inhibition for treatment of leishmaniasis, Chagas disease and sleeping sickness.
Nature
Khare S,Nagle AS,Biggart A,Lai YH,Liang F,Davis LC,Barnes SW,Mathison CJ,Myburgh E,Gao MY,Gillespie JR,Liu X,Tan JL,Stinson M,Rivera IC,Ballard J,Yeh V,Groessl T,Federe G,Koh HX,Venable JD,Bursulaya B,Shapiro M,Mishra PK,Spraggon G,Brock A,Mottram JC,Buckner FS,Rao SP,Wen BG,Walker JR,Tuntland T,Molteni V,Glynne RJ,Supek F
Thu Sep 08 00:00:00 EDT 2016
Proteasome inhibition for treatment of leishmaniasis, Chagas disease and sleeping sickness.
Nature
Khare S,Nagle AS,Biggart A,Lai YH,Liang F,Davis LC,Barnes SW,Mathison CJ,Myburgh E,Gao MY,Gillespie JR,Liu X,Tan JL,Stinson M,Rivera IC,Ballard J,Yeh V,Groessl T,Federe G,Koh HX,Venable JD,Bursulaya B,Shapiro M,Mishra PK,Spraggon G,Brock A,Mottram JC,Buckner FS,Rao SP,Wen BG,Walker JR,Tuntland T,Molteni V,Glynne RJ,Supek F
Thu Sep 08 00:00:00 EDT 2016
The Ubiquitin-like Protein FAT10 Stabilizes eEF1A1 Expression to Promote Tumor Proliferation in a Complex Manner.
Cancer research
Liu X,Chen L,Ge J,Yan C,Huang Z,Hu J,Wen C,Li M,Huang D,Qiu Y,Hao H,Yuan R,Lei J,Yu X,Shao J
Mon Aug 15 00:00:00 EDT 2016
The Ubiquitin-like Protein FAT10 Stabilizes eEF1A1 Expression to Promote Tumor Proliferation in a Complex Manner.
Cancer research
Liu X,Chen L,Ge J,Yan C,Huang Z,Hu J,Wen C,Li M,Huang D,Qiu Y,Hao H,Yuan R,Lei J,Yu X,Shao J
Mon Aug 15 00:00:00 EDT 2016
Far-infrared promotes burn wound healing by suppressing NLRP3 inflammasome caused by enhanced autophagy.
Journal of molecular medicine (Berlin, Germany)
Chiu HW,Chen CH,Chang JN,Chen CH,Hsu YH
Fri Jul 01 00:00:00 EDT 2016
Far-infrared promotes burn wound healing by suppressing NLRP3 inflammasome caused by enhanced autophagy.
Journal of molecular medicine (Berlin, Germany)
Chiu HW,Chen CH,Chang JN,Chen CH,Hsu YH
Fri Jul 01 00:00:00 EDT 2016
Proteomic analysis of apoptosis induction by lariciresinol in human HepG2 cells.
Chemico-biological interactions
Ma ZJ,Wang XX,Su G,Yang JJ,Zhu YJ,Wu YW,Li J,Lu L,Zeng L,Pei HX
Thu Aug 25 00:00:00 EDT 2016
Proteomic analysis of apoptosis induction by lariciresinol in human HepG2 cells.
Chemico-biological interactions
Ma ZJ,Wang XX,Su G,Yang JJ,Zhu YJ,Wu YW,Li J,Lu L,Zeng L,Pei HX
Thu Aug 25 00:00:00 EDT 2016
Phosphorylation of TOPK at Y74, Y272 by Src increases the stability of TOPK and promotes tumorigenesis of colon.
Oncotarget
Xiao J,Duan Q,Wang Z,Yan W,Sun H,Xue P,Fan X,Zeng X,Chen J,Shao C,Zhu F
Tue Apr 26 00:00:00 EDT 2016
Phosphorylation of TOPK at Y74, Y272 by Src increases the stability of TOPK and promotes tumorigenesis of colon.
Oncotarget
Xiao J,Duan Q,Wang Z,Yan W,Sun H,Xue P,Fan X,Zeng X,Chen J,Shao C,Zhu F
Tue Apr 26 00:00:00 EDT 2016
Nogo-B receptor promotes the chemoresistance of human hepatocellular carcinoma via the ubiquitination of p53 protein.
Oncotarget
Dong C,Zhao B,Long F,Liu Y,Liu Z,Li S,Yang X,Sun D,Wang H,Liu Q,Liang R,Li Y,Gao Z,Shao S,Miao QR,Wang L
Tue Feb 23 00:00:00 EST 2016
The N-Terminal of Aquareovirus NS80 Is Required for Interacting with Viral Proteins and Viral Replication.
PloS one
Zhang J,Guo H,Chen Q,Zhang F,Fang Q
Thu Jul 14 00:00:00 EDT 2016
The N-Terminal of Aquareovirus NS80 Is Required for Interacting with Viral Proteins and Viral Replication.
PloS one
Zhang J,Guo H,Chen Q,Zhang F,Fang Q
Thu Jul 14 00:00:00 EDT 2016
Human respiratory syncytial virus infection is inhibited by IFN-induced transmembrane proteins.
The Journal of general virology
Zhang W,Zhang L,Zan Y,Du N,Yang Y,Tien P
Thu Jan 01 00:00:00 EST 2015
Human respiratory syncytial virus infection is inhibited by IFN-induced transmembrane proteins.
The Journal of general virology
Zhang W,Zhang L,Zan Y,Du N,Yang Y,Tien P
Thu Jan 01 00:00:00 EST 2015
DEC1 regulates breast cancer cell proliferation by stabilizing cyclin E protein and delays the progression of cell cycle S phase.
Cell death & disease
Bi H,Li S,Qu X,Wang M,Bai X,Xu Z,Ao X,Jia Z,Jiang X,Yang Y,Wu H
Thu Sep 24 00:00:00 EDT 2015
The oncoprotein HBXIP promotes glucose metabolism reprogramming via downregulating SCO2 and PDHA1 in breast cancer.
Oncotarget
Liu F,Zhang W,You X,Liu Y,Li Y,Wang Z,Wang Y,Zhang X,Ye L
Tue Sep 29 00:00:00 EDT 2015
The oncoprotein HBXIP promotes glucose metabolism reprogramming via downregulating SCO2 and PDHA1 in breast cancer.
Oncotarget
Liu F,Zhang W,You X,Liu Y,Li Y,Wang Z,Wang Y,Zhang X,Ye L
Tue Sep 29 00:00:00 EDT 2015
The oncoprotein HBXIP modulates the feedback loop of MDM2/p53 to enhance the growth of breast cancer.
The Journal of biological chemistry
Li H,Liu Q,Wang Z,Fang R,Shen Y,Cai X,Gao Y,Li Y,Zhang X,Ye L
Fri Sep 11 00:00:00 EDT 2015
The oncoprotein HBXIP modulates the feedback loop of MDM2/p53 to enhance the growth of breast cancer.
The Journal of biological chemistry
Li H,Liu Q,Wang Z,Fang R,Shen Y,Cai X,Gao Y,Li Y,Zhang X,Ye L
Fri Sep 11 00:00:00 EDT 2015
Protein tyrosine phosphatase receptor U (PTPRU) is required for glioma growth and motility.
Carcinogenesis
Zhu Z,Liu Y,Li K,Liu J,Wang H,Sun B,Xiong Z,Jiang H,Zheng J,Hu Z
Fri Aug 01 00:00:00 EDT 2014
Protein tyrosine phosphatase receptor U (PTPRU) is required for glioma growth and motility.
Carcinogenesis
Zhu Z,Liu Y,Li K,Liu J,Wang H,Sun B,Xiong Z,Jiang H,Zheng J,Hu Z
Fri Aug 01 00:00:00 EDT 2014
Clinicopathologic report of ocular involvement in ALS patients with C9orf72 mutation.
Amyotrophic lateral sclerosis & frontotemporal degeneration
Fawzi AA,Simonett JM,Purta P,Moss HE,Lowry JL,Deng HX,Siddique N,Sufit R,Bigio EH,Volpe NJ,Siddique T
Mon Dec 01 00:00:00 EST 2014
Clinicopathologic report of ocular involvement in ALS patients with C9orf72 mutation.
Amyotrophic lateral sclerosis & frontotemporal degeneration
Fawzi AA,Simonett JM,Purta P,Moss HE,Lowry JL,Deng HX,Siddique N,Sufit R,Bigio EH,Volpe NJ,Siddique T
Mon Dec 01 00:00:00 EST 2014
Rock2 promotes the invasion and metastasis of hepatocellular carcinoma by modifying MMP2 ubiquitination and degradation.
Biochemical and biophysical research communications
Huang D,Du X,Yuan R,Chen L,Liu T,Wen C,Huang M,Li M,Hao L,Shao J
Fri Oct 10 00:00:00 EDT 2014
Rock2 promotes the invasion and metastasis of hepatocellular carcinoma by modifying MMP2 ubiquitination and degradation.
Biochemical and biophysical research communications
Huang D,Du X,Yuan R,Chen L,Liu T,Wen C,Huang M,Li M,Hao L,Shao J
Fri Oct 10 00:00:00 EDT 2014
Rock2 promotes the invasion and metastasis of hepatocellular carcinoma by modifying MMP2 ubiquitination and degradation.
Biochemical and biophysical research communications
Huang D,Du X,Yuan R,Chen L,Liu T,Wen C,Huang M,Li M,Hao L,Shao J
Fri Oct 10 00:00:00 EDT 2014
Rock2 promotes the invasion and metastasis of hepatocellular carcinoma by modifying MMP2 ubiquitination and degradation.
Biochemical and biophysical research communications
Huang D,Du X,Yuan R,Chen L,Liu T,Wen C,Huang M,Li M,Hao L,Shao J
Fri Oct 10 00:00:00 EDT 2014
Ubiquitin B in cervical cancer: critical for the maintenance of cancer stem-like cell characters.
PloS one
Tian Y,Ding W,Wang Y,Ji T,Sun S,Mo Q,Chen P,Fang Y,Liu J,Wang B,Zhou J,Ma D,Wu P
Mon Oct 13 00:00:00 EDT 2014
Ubiquitin B in cervical cancer: critical for the maintenance of cancer stem-like cell characters.
PloS one
Tian Y,Ding W,Wang Y,Ji T,Sun S,Mo Q,Chen P,Fang Y,Liu J,Wang B,Zhou J,Ma D,Wu P
Mon Oct 13 00:00:00 EDT 2014
Amyloid precursor protein accumulates in aggresomes in response to proteasome inhibitor.
Neurochemistry international
Dehvari N,Mahmud T,Persson J,Bengtsson T,Graff C,Winblad B,Rönnbäck A,Behbahani H
Sun Apr 01 00:00:00 EDT 2012
Amyloid precursor protein accumulates in aggresomes in response to proteasome inhibitor.
Neurochemistry international
Dehvari N,Mahmud T,Persson J,Bengtsson T,Graff C,Winblad B,Rönnbäck A,Behbahani H
Sun Apr 01 00:00:00 EDT 2012
Downregulation of the ubiquitin-proteasome system in normal colonic macrophages and reinduction in inflammatory bowel disease.
Digestion
Hetzenecker AM,Seidl MC,Kosovac K,Herfarth H,Kellermeier S,Obermeier F,Falk W,Schoelmerich J,Hausmann M,Rogler G
Thu Jan 17 00:00:00 EST 2013
Downregulation of the ubiquitin-proteasome system in normal colonic macrophages and reinduction in inflammatory bowel disease.
Digestion
Hetzenecker AM,Seidl MC,Kosovac K,Herfarth H,Kellermeier S,Obermeier F,Falk W,Schoelmerich J,Hausmann M,Rogler G
Thu Jan 17 00:00:00 EST 2013
Downregulation of the ubiquitin-proteasome system in normal colonic macrophages and reinduction in inflammatory bowel disease.
Digestion
Hetzenecker AM,Seidl MC,Kosovac K,Herfarth H,Kellermeier S,Obermeier F,Falk W,Schoelmerich J,Hausmann M,Rogler G
Thu Jan 17 00:00:00 EST 2013
Downregulation of the ubiquitin-proteasome system in normal colonic macrophages and reinduction in inflammatory bowel disease.
Digestion
Hetzenecker AM,Seidl MC,Kosovac K,Herfarth H,Kellermeier S,Obermeier F,Falk W,Schoelmerich J,Hausmann M,Rogler G
Thu Jan 17 00:00:00 EST 2013