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Immunogen sequence: MSAPAQPPA EGTEGTAPGG GPPGPPPNMT SNRRLQQTQA QVEEVVDIIR VNVDKVLERD QKLSELDDRA DALQAGASQF ESSAAKLKRK YWWKNCKMMI M (1-100 aa encoded by BC023286)
Synapotobrevins, syntaxins, and the synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Mutations in this gene are associated with autosomal dominant spastic ataxia 1. Multiple alternative splice variants have been described, but the full-length nature of some variants has not been defined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: DKFZp686H12131; MRXSYP; synaptobrevin 1; Synaptobrevin-1; vamp; VAMP-1; Vesicle-associated membrane protein 1; vesicle-associated membrane protein 1 (synaptobrevin 1)
基因别名: lew; SPAX1; Syb-1; SYB1; VAMP-1; VAMP1
UniProt ID: (Human) P23763, (Mouse) Q62442, (Rat) Q63666
Entrez Gene ID: (Human) 6843, (Mouse) 22317, (Rat) 25624