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VAMP1/VAMP2/VAMP3 Antibody (PA5-103178) in ICC/IF
Immunocytochemistry analysis of VAMP1/VAMP2/VAMP3 in A549 cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with VAMP1/VAMP2/VAMP3 polyclonal antibody (Product # PA5-103178) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG (Red) and an AlexaFluor488 c... View More
产品信息
PA5-103178
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human VAMP 1/2/3, corresponding to a region within C-terminal amino acids.
偶联物
Unconjugated
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2815956
产品详细信息
Antibody detects endogenous levels of total VAMP 1/2/3.
靶标信息
Synapotobrevins, syntaxins, and the synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Mutations in this gene are associated with autosomal dominant spastic ataxia 1. Multiple alternative splice variants have been described, but the full-length nature of some variants has not been defined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CEB; Cellubrevin; synaptobrevin 1; synaptobrevin 2; Synaptobrevin 2 (vesicle-associated membrane protein VAMP-2); synaptobrevin II; Synaptobrevin-1; Synaptobrevin-2; Synaptobrevin-3; VAMP-1; VAMP-2; VAMP-3; vesicle-associated membrane 2; Vesicle-associated membrane protein (synaptobrevin 2); Vesicle-associated membrane protein 1; vesicle-associated membrane protein 1 (synaptobrevin 1); Vesicle-associated membrane protein 2; vesicle-associated membrane protein 2 (synaptobrevin 2); Vesicle-associated membrane protein 3
基因别名: CEB; D130027G05Rik; lew; RATVAMPB; RATVAMPIR; SPAX1; SYB; Syb-1; Syb-2; SYB1; SYB2; SYB3; sybII; VAMP-1; VAMP-2; VAMP-3; VAMP1; VAMP2; VAMP3
UniProt ID: (Human) P23763, (Human) P63027, (Human) Q15836, (Mouse) Q62442, (Rat) Q63666, (Mouse) P63044, (Rat) P63045, (Mouse) P63024, (Rat) P63025
Entrez Gene ID: (Human) 6843, (Human) 6844, (Human) 9341, (Mouse) 22317, (Rat) 25624, (Mouse) 22318, (Rat) 24803, (Mouse) 22319, (Rat) 29528
positive regulation of receptor recycling
protein complex assembly
transport
vesicle fusion
protein transport
vesicle-mediated transport
calcium ion regulated exocytosis
substrate adhesion-dependent cell spreading
SNARE complex assembly
retrograde transport, endosome to Golgi
Golgi to plasma membrane protein transport
negative regulation of secretion by cell
exocytosis
response to glucose
synaptic vesicle exocytosis
regulation of exocytosis
regulation of calcium ion-dependent exocytosis
cellular response to insulin stimulus
eosinophil degranulation
long-term synaptic potentiation
regulation of vesicle-mediated transport
membrane fusion
positive regulation of intracellular protein transport
regulation of delayed rectifier potassium channel activity
neurotransmitter secretion
neutrophil degranulation
natural killer cell degranulation
mucus secretion
regulation of histamine secretion by mast cell
vesicle docking involved in exocytosis
positive regulation of immunoglobulin secretion
intracellular protein transport
post-Golgi vesicle-mediated transport
glutamate secretion
