Invitrogen

VAV1 Polyclonal Antibody

高级验证

This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.

查看其他22个VAV1抗体

说明书

实验方案

技术支持

说明书

实验方案

技术支持

抗体检测数据 (2)
高级验证 (1)

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VAV1 Antibody (PA5-17834) in WB

Western blot was performed using Anti-VAV1 Polyclonal Antibody (Product # PA5-17834) and a 98 kDa band corresponding to VAV1 was observed in Raji, MOLT-4, Jurkat, THP-1, Mouse Thymus but not in T-47D, MCF7 and Mouse Kidney. Whole cell extracts (30 µg) of Raji (Lane 1), MOLT-4 (Lane 2), Jurkat (Lane 3), THP-1 (Lane 4), T-47D (Lane 5) and MCF7 (Lane 6), and Tissue extracts (30 µg) of Mouse Thymus (Lane 7) and Mouse Kidney (Lane 8) were electrophoresed using NuPAGE® 10 % Bis-Tris gel (Product # NP0302BOX). Resolved proteins were then transfer... View More

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VAV1 Antibody — Antibody specificity was demonstrated by detection of differential basal expression of the target across cell lines and tissues owing to their inherent genetic constitution. Relative expression of VAV1 was observed in Raji, MOLT-4, Jurkat, THP-1 and Mouse Thymus, not in T-47D, MCF7 and Mouse Kidney using VAV1 Polyclonal Antibody (Product # PA5-17834) in western blot. {RE}

产品信息

PA5-17834

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000

流式细胞分析 (Flow)

1:25

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Synthetic peptide corresponding to residues surrounding Tyr174 of human Vav

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

27 µg/mL

纯化类型

Antigen affinity chromatography

保存液

0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol

内含物

no preservative

保存条件

-20°C

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_10987031

产品详细信息

It is not recommended to aliquot this antibody.

This antibody is not cross-reactive with Vav2, Vav3 or CelVav.

靶标信息

This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein.

仅用于科研。不用于诊断过程。未经明确授权不得转售。