Search Thermo Fisher Scientific
Invitrogen
This Antibody was verified by Knockout to ensure that the antibody binds to the antigen stated.
图: 1 / 5
Immunogen sequence: MAVPPTYADL GKSARDVFTK GYGFGLIKLD LKTKSENGLE FTSSGSANTE TTKVTGSLET KYRWTEYGLT FTEKWNTDNT LGTEITVEDQ LARGLKLTFD
Voltage-dependent anion channel (VDAC) proteins are abundant, pore-forming proteins belonging to the eukaryotic mitochondrial porins. It was discovered in the mitochondrial outer membrane. It also is expressed in the plasma membrane. At least three different VDAC genes have been identified in vertebrates. VDAC proteins are known to play an essential role in cellular metabolism and in the early stages of apoptosis. For example, VDAC constitutes a major pathway by which metabolites such as ADP/ATP, succinate and citrate are exchanged between the cytosol and mitochondria. And VDAC1 in the plasma membrane establishes a novel level of apoptosis regulation putatively via its redox activity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: hVDAC1; MGC111064; Mitochondrial Porin; mVDAC1; mVDAC5; Non-selective voltage-gated ion channel VDAC1; Outer mitochondrial membrane protein porin 1; Plasmalemmal porin; Porin 31HL; Porin 31HM; PORIN-31-HL; rVDAC1; VD; VDAC-1; VDAC-5; Voltage-dependent anion-selective channel protein 1; Voltage-dependent anion-selective channel protein 5
基因别名: AL033343; PORIN; VDAC; VDAC-1; VDAC1; Vdac5
UniProt ID: (Human) P21796, (Mouse) Q60932, (Rat) Q9Z2L0
Entrez Gene ID: (Human) 7416, (Mouse) 22333, (Rat) 83529