Osenses

VPS29 Polyclonal Antibody

产品信息

OSV00030G-500UG

应用

建议稀释比

已发表文章

免疫印迹 (WB)

10-50 µg/mL

免疫组化 (IHC)

10-50 µg/mL

其他PubMed (Misc)

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产品规格

种属反应

Human, Mouse, Rat

已发表种属

Not Applicable

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

A synthetic peptide from the c-terminal region of mouse VPS29 conjugated to an immunogenic carrier protein was used as the antigen

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Lyophilized

浓度

Conc. Not Determined

纯化类型

Ammonium sulfate precipitation

保存液

PBS

内含物

no preservative

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.

The peptide is homologous in rat, human, chicken, zebra fish and xenopus.

Specificity of this antibody: VPS29.

靶标信息

This gene belongs to a group of vacuolar protein sorting genes that, when functionally impaired, disrupt the efficient delivery of vacuolar hydrolases. The protein encoded by this gene is a component of a large multimeric complex, termed the retromer complex, which is involved in retrograde transport of proteins from endosomes to the trans-Golgi network. This VPS protein may be involved in the formation of the inner shell of the retromer coat for retrograde vesicles leaving the prevacuolar compartment. Alternative splice variants encoding different isoforms, and usage of multiple polyadenylation sites have been found for this gene.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

The transcriptional landscape of the mammalian genome.

Science (New York, N.Y.)

Carninci P,Kasukawa T,Katayama S,Gough J,Frith MC,Maeda N,Oyama R,Ravasi T,Lenhard B,Wells C,Kodzius R,Shimokawa K,Bajic VB,Brenner SE,Batalov S,Forrest AR,Zavolan M,Davis MJ,Wilming LG,Aidinis V,Allen JE,Ambesi-Impiombato A,Apweiler R,Aturaliya RN,Bailey TL,Bansal M,Baxter L,Beisel KW,Bersano T,Bono H,Chalk AM,Chiu KP,Choudhary V,Christoffels A,Clutterbuck DR,Crowe ML,Dalla E,Dalrymple BP,de Bono B,Della Gatta G,di Bernardo D,Down T,Engstrom P,Fagiolini M,Faulkner G,Fletcher CF,Fukushima T,Furuno M,Futaki S,Gariboldi M,Georgii-Hemming P,Gingeras TR,Gojobori T,Green RE,Gustincich S,Harbers M,Hayashi Y,Hensch TK,Hirokawa N,Hill D,Huminiecki L,Iacono M,Ikeo K,Iwama A,Ishikawa T,Jakt M,Kanapin A,Katoh M,Kawasawa Y,Kelso J,Kitamura H,Kitano H,Kollias G,Krishnan SP,Kruger A,Kummerfeld SK,Kurochkin IV,Lareau LF,Lazarevic D,Lipovich L,Liu J,Liuni S,McWilliam S,Madan Babu M,Madera M,Marchionni L,Matsuda H,Matsuzawa S,Miki H,Mignone F,Miyake S,Morris K,Mottagui-Tabar S,Mulder N,Nakano N,Nakauchi H,Ng P,Nilsson R,Nishiguchi S,Nishikawa S,Nori F,Ohara O,Okazaki Y,Orlando V,Pang KC,Pavan WJ,Pavesi G,Pesole G,Petrovsky N,Piazza S,Reed J,Reid JF,Ring BZ,Ringwald M,Rost B,Ruan Y,Salzberg SL,Sandelin A,Schneider C,Schönbach C,Sekiguchi K,Semple CA,Seno S,Sessa L,Sheng Y,Shibata Y,Shimada H,Shimada K,Silva D,Sinclair B,Sperling S,Stupka E,Sugiura K,Sultana R,Takenaka Y,Taki K,Tammoja K,Tan SL,Tang S,Taylor MS,Tegner J,Teichmann SA,Ueda HR,van Nimwegen E,Verardo R,Wei CL,Yagi K,Yamanishi H,Zabarovsky E,Zhu S,Zimmer A,Hide W,Bult C,Grimmond SM,Teasdale RD,Liu ET,Brusic V,Quackenbush J,Wahlestedt C,Mattick JS,Hume DA,Kai C,Sasaki D,Tomaru Y,Fukuda S,Kanamori-Katayama M,Suzuki M,Aoki J,Arakawa T,Iida J,Imamura K,Itoh M,Kato T,Kawaji H,Kawagashira N,Kawashima T,Kojima M,Kondo S,Konno H,Nakano K,Ninomiya N,Nishio T,Okada M,Plessy C,Shibata K,Shiraki T,Suzuki S,Tagami M,Waki K,Watahiki A,Okamura-Oho Y,Suzuki H,Kawai J,Hayashizaki Y

Fri Sep 02 00:00:00 EDT 2005

Vps29 has a phosphoesterase fold that acts as a protein interaction scaffold for retromer assembly.

Nature structural & molecular biology

Collins BM,Skinner CF,Watson PJ,Seaman MN,Owen DJ

Fri Jul 01 00:00:00 EDT 2005

生物信息学

蛋白别名: DKFZp564F0223; FLJ20492; hVPS29; PEP11 homolog; retromer protein; vacuolar protein sorting 29 homolog; Vacuolar protein sorting-associated protein 29; vacuolar protein sorting-associated protein 29 {ECO:0000250|UniProtKB:Q9UBQ0}; vacuolar sorting protein 29; vacuolar sorting protein VPS29/PEP11; Vesicle protein sorting 29; vesicle protein sorting 29 {ECO:0000250|UniProtKB:Q9UBQ0}; VPS29 retromer complex component; vps29 {ECO:0000312|EMBL:AAI67055.1, ECO:0000312|RGD:1308332}; x 007 protein

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基因别名: 2010015D08Rik; AW049835; DC15; DC7; MDS007; PEP11; VPS29

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UniProt ID: (Human) Q9UBQ0, (Rat) B2RZ78, (Mouse) Q9QZ88

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Entrez Gene ID: (Human) 51699, (Rat) 288666, (Mouse) 56433

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功能

protein binding protein transporter activity metal ion binding zinc ion binding membrane traffic protein vesicle coat protein

参与通路

intracellular protein transport Wnt signaling pathway retrograde transport, endosome to Golgi retrograde transport, endosome to plasma membrane transport Golgi to vacuole transport protein transport