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Immunogen sequence: CPYCGNSLPVE EHVGSQTFVN PHVSSFQGSK RGLNSSFETS PKKVKWSSTV TSPRLSLFSD GDSSESEDTL SS
Highest antigen sequence identity to the following orthologs - mouse 68%, rat 73%.
This gene encodes a member of the vaccinia-related kinase family of serine/threonine protein kinases. In both human and mouse, this gene has substitutions at several residues within the ATP binding motifs that in other kinases have been shown to be required for catalysis. In vitro assays indicate the protein lacks phosphorylation activity. The protein, however, likely retains its substrate binding capability. This gene is widely expressed in human tissues and its protein localizes to the nucleus. Alternative splicing results in multiple transcripts encoding different isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Serine/threonine-protein kinase VRK3; serine/threonine-protein pseudokinase VRK3; Vaccinia-related kinase 3
基因别名: VRK3
UniProt ID: (Human) Q502Y2
Entrez Gene ID: (Human) 51231