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产品信息
H00007448-B01P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
VTN (AAH05046.1, 1 a.a. approximately 478 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MAPLRPLLIL ALLAWVALAD QESCKGRCTE GFNVDKKCQC DELCSYYQSC CTDYTAECKP QVTRGDVFTM PEDEYTVYDD GEEKNNATVH EQVGGPSLTS DLQAQSKGNP EQTPVLKPEE EAPAPEVGAS KPEGIDSRPE TLHPGRPQPP AEEELCSGKP FDAFTDLKNG SLFAFRGQYC YELDEKAVRP GYPKLIRDVW GIEGPIDAAF TRINCQGKTY LFKGSQYWRF EDGVLDPDYP RNISDGFDGI PDNVDAALAL PAHSYSGRER VYFFKGKQYW EYQFQHQPSQ EECEGSSLSA VFEHFAMMQR DSWEDIFELL FWGRTSAGTR QPQFISRDWH GVPGQVDAAM AGRIYISGMA PRPSLAKKQR FRHRNRKGYR SQRGHSRGRN QNSRRPSRAM WLSLFSSEES NLGANNYDDY RMDWLVPATC EPIQSVFFFS GDKYYRVNLR TRRVDTVDPP YPRSIAQYWL GCPAPGHL
靶标信息
VTN is a member of the pexin family. This protein is found in serum and tissues and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. The protein is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: complement S-protein; epibolin; S-protein; serum spreading factor; Serum-spreading factor; somatomedin B; V75; Vitronectin; VN
基因别名: V75; VN; VNT; VTN
UniProt ID: (Human) P04004
Entrez Gene ID: (Human) 7448
receptor-mediated endocytosis
immune response
cell adhesion
cell-matrix adhesion
positive regulation of cell-substrate adhesion
negative regulation of endopeptidase activity
positive regulation of smooth muscle cell migration
negative regulation of blood coagulation
extracellular matrix organization
regulation of complement activation
positive regulation of vascular endothelial growth factor receptor signaling pathway
positive regulation of protein binding
cell adhesion mediated by integrin
endodermal cell differentiation
positive regulation of receptor-mediated endocytosis
oligodendrocyte differentiation
positive regulation of peptidyl-tyrosine phosphorylation
smooth muscle cell-matrix adhesion
positive regulation of wound healing
