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WDR61 Antibody (TA807588) in WB
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY WDR61 (RC203963, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-WDR61. Positive lysates LY410745 (100 µg) and LC410745 (20 µg) can be purchased separately from OriGene.
产品信息
TA807588
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
OTI1D4
抗原
Human recombinant protein fragment corresponding to amino acids 92-305 of human WDR61 produced in E.coli.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS with 1% BSA, 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
SKI8 is a component of the PAF and SKI complex which is composed of SKI2, SKI3 and SKI8. These are involved in transcriptional regulation and events downstream of RNA synthesis. Interaction of the SKI complex with SKI7 links the SKI complex to the exosome in order to perform mRNA degradation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Meiotic recombination REC14 protein homolog; recombination protein REC14; Ski8; SKI8 homolog; Superkiller complex protein 8; WD repeat-containing protein 61
基因别名: REC14; SKI8; SKIC8; WDR61
UniProt ID: (Human) Q9GZS3
Entrez Gene ID: (Human) 80349
transcription, DNA-templated
Wnt signaling pathway
positive regulation of transcription elongation from RNA polymerase II promoter
negative regulation of myeloid cell differentiation
positive regulation of transcription from RNA polymerase II promoter
positive regulation of histone H3-K4 methylation
histone H3-K4 trimethylation
positive regulation of histone H3-K79 methylation
